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Chronic hepatic encephalopathy

MedGen UID:
870490
•Concept ID:
C4024937
•
Disease or Syndrome
HPO: HP:0007111

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic hepatic encephalopathy

Conditions with this feature

Splenoportal vascular anomaly
MedGen UID:
137945
•Concept ID:
C0340826
•
Congenital Abnormality
See: Condition Record
Splenoportal vascular anomaly

Professional guidelines

PubMed

Pathophysiology, diagnosis and treatment of ascites in cirrhosis.
Arroyo V
Ann Hepatol 2002 Apr-Jun;1(2):72-9. PMID: 15115971
Treatment of chronic hepatic encephalopathy.
Lancet 1970 Aug 29;2(7670):449-50. PMID: 4195121
Treatment of chronic hepatic encephalopathy with lactulose.
Fung WP, Khoo OT
Med J Aust 1968 Jul 27;2(4):160-3. doi: 10.5694/j.1326-5377.1968.tb29379.x. PMID: 5670884

Recent clinical studies

Etiology

Probiotics for people with hepatic encephalopathy.
Dalal R, McGee RG, Riordan SM, Webster AC
Cochrane Database Syst Rev 2017 Feb 23;2(2):CD008716. doi: 10.1002/14651858.CD008716.pub3. PMID: 28230908Free PMC Article
Concomitant hepatic encephalopathy and refractory ascites: successful treatment with staged embolization of two large portosystemic shunts and transjugular intrahepatic portosystemic shunt placement.
Smith JC, Black MD, Mendler MH
J Vasc Interv Radiol 2007 Nov;18(11):1441-6. doi: 10.1016/j.jvir.2007.07.023. PMID: 18003997
Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy.
Als-Nielsen B, Kjaergard LL, Gluud C
Cochrane Database Syst Rev 2001;(4):CD002798. doi: 10.1002/14651858.CD002798. PMID: 11687160
A controlled study of therapeutic portacaval shunt in alcoholic cirrhosis.
Rueff B, Prandi D, Degos F, Sicot J, Degos JD, Sicot C, Maillard JN, Fauvert R, Benhamou JP
Lancet 1976 Mar 27;1(7961):655-9. doi: 10.1016/s0140-6736(76)92775-6. PMID: 73637
Surgical exclusion of the colon for chronic hepatic encephalopathy.
Dudrick SJ, Mackie JA, Serlin O
Am J Surg 1968 Jan;115(1):57-62. doi: 10.1016/0002-9610(68)90129-3. PMID: 5634675

Diagnosis

Study on Precipitating Factor of Chronic Hepatic Encephalopathy.
Ali MH, Kabir MA, Islam MS, Rahim CM, Hasan MK, Islam MK, Hasan MR, Alam MS
Mymensingh Med J 2020 Oct;29(4):800-806. PMID: 33116080
Wernicke encephalopathy and ethanol-related syndromes.
Kim TE, Lee EJ, Young JB, Shin DJ, Kim JH
Semin Ultrasound CT MR 2014 Apr;35(2):85-96. doi: 10.1053/j.sult.2013.09.004. PMID: 24745886
Pathophysiology, diagnosis and treatment of ascites in cirrhosis.
Arroyo V
Ann Hepatol 2002 Apr-Jun;1(2):72-9. PMID: 15115971
Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy.
Als-Nielsen B, Kjaergard LL, Gluud C
Cochrane Database Syst Rev 2001;(4):CD002798. doi: 10.1002/14651858.CD002798. PMID: 11687160
Recognition and management of acute and chronic hepatic encephalopathy.
Jacobson S, Bell B
Med Clin North Am 1973 Nov;57(6):1569-77. doi: 10.1016/s0025-7125(16)32211-8. PMID: 4583596

Therapy

Pathophysiology, diagnosis and treatment of ascites in cirrhosis.
Arroyo V
Ann Hepatol 2002 Apr-Jun;1(2):72-9. PMID: 15115971
Review article: pathogenesis and treatment of chronic hepatic encephalopathy.
Jalan R, Seery JP, Taylor-Robinson SD
Aliment Pharmacol Ther 1996 Oct;10(5):681-97. doi: 10.1046/j.1365-2036.1996.58200000.x. PMID: 8899075
Bromocriptine-associated ototoxicity.
Lanthier PL, Morgan MY, Ballantyne J
J Laryngol Otol 1984 Apr;98(4):399-404. doi: 10.1017/s0022215100146808. PMID: 6715973
Recognition and management of acute and chronic hepatic encephalopathy.
Jacobson S, Bell B
Med Clin North Am 1973 Nov;57(6):1569-77. doi: 10.1016/s0025-7125(16)32211-8. PMID: 4583596
Treatment of chronic hepatic encephalopathy.
Lancet 1970 Aug 29;2(7670):449-50. PMID: 4195121

Prognosis

Probiotics for people with hepatic encephalopathy.
Dalal R, McGee RG, Riordan SM, Webster AC
Cochrane Database Syst Rev 2017 Feb 23;2(2):CD008716. doi: 10.1002/14651858.CD008716.pub3. PMID: 28230908Free PMC Article
Pathophysiology, diagnosis and treatment of ascites in cirrhosis.
Arroyo V
Ann Hepatol 2002 Apr-Jun;1(2):72-9. PMID: 15115971
Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy.
Als-Nielsen B, Kjaergard LL, Gluud C
Cochrane Database Syst Rev 2001;(4):CD002798. doi: 10.1002/14651858.CD002798. PMID: 11687160
A controlled study of therapeutic portacaval shunt in alcoholic cirrhosis.
Rueff B, Prandi D, Degos F, Sicot J, Degos JD, Sicot C, Maillard JN, Fauvert R, Benhamou JP
Lancet 1976 Mar 27;1(7961):655-9. doi: 10.1016/s0140-6736(76)92775-6. PMID: 73637
Surgical exclusion of the colon for chronic hepatic encephalopathy.
Dudrick SJ, Mackie JA, Serlin O
Am J Surg 1968 Jan;115(1):57-62. doi: 10.1016/0002-9610(68)90129-3. PMID: 5634675

Clinical prediction guides

Oral L-ornithine-L-aspartate therapy of chronic hepatic encephalopathy: results of a placebo-controlled double-blind study.
Stauch S, Kircheis G, Adler G, Beckh K, Ditschuneit H, Görtelmeyer R, Hendricks R, Heuser A, Karoff C, Malfertheiner P, Mayer D, Rösch W, Steffens J
J Hepatol 1998 May;28(5):856-64. doi: 10.1016/s0168-8278(98)80237-7. PMID: 9625322
Overview of randomized clinical trials of oral branched-chain amino acid treatment in chronic hepatic encephalopathy.
Fabbri A, Magrini N, Bianchi G, Zoli M, Marchesini G
JPEN J Parenter Enteral Nutr 1996 Mar-Apr;20(2):159-64. doi: 10.1177/0148607196020002159. PMID: 8676537
Manganese and chronic hepatic encephalopathy.
Krieger D, Krieger S, Jansen O, Gass P, Theilmann L, Lichtnecker H
Lancet 1995 Jul 29;346(8970):270-4. doi: 10.1016/s0140-6736(95)92164-8. PMID: 7630246
Lactitol in the treatment of chronic hepatic encephalopathy--a randomized cross-over comparison with lactulose.
Riggio O, Balducci G, Ariosto F, Merli M, Tremiterra S, Ziparo V, Capocaccia L
Hepatogastroenterology 1990 Oct;37(5):524-7. PMID: 2253931
Some observations on the effects of treatment with lactulose on patients with chronic hepatic encephalopathy.
Zeegen R, Drinkwater JE, Fenton JC, Vince A, Dawson AM
Q J Med 1970 Apr;39(154):245-63. PMID: 5449591

Recent systematic reviews

Portosystemic shunts versus endoscopic intervention with or without medical treatment for prevention of rebleeding in people with cirrhosis.
Simonetti RG, Perricone G, Robbins HL, Battula NR, Weickert MO, Sutton R, Khan S
Cochrane Database Syst Rev 2020 Oct 22;10(10):CD000553. doi: 10.1002/14651858.CD000553.pub3. PMID: 33089892Free PMC Article
Probiotics for people with hepatic encephalopathy.
Dalal R, McGee RG, Riordan SM, Webster AC
Cochrane Database Syst Rev 2017 Feb 23;2(2):CD008716. doi: 10.1002/14651858.CD008716.pub3. PMID: 28230908Free PMC Article
Probiotics for patients with hepatic encephalopathy.
McGee RG, Bakens A, Wiley K, Riordan SM, Webster AC
Cochrane Database Syst Rev 2011 Nov 9;(11):CD008716. doi: 10.1002/14651858.CD008716.pub2. PMID: 22071855
Dopaminergic agonists for hepatic encephalopathy.
Als-Nielsen B, Gluud LL, Gluud C
Cochrane Database Syst Rev 2004 Oct 18;(4):CD003047. doi: 10.1002/14651858.CD003047.pub2. PMID: 15495041
Benzodiazepine receptor antagonists for acute and chronic hepatic encephalopathy.
Als-Nielsen B, Kjaergard LL, Gluud C
Cochrane Database Syst Rev 2001;(4):CD002798. doi: 10.1002/14651858.CD002798. PMID: 11687160

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