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Abnormal gastric mucosa morphology

MedGen UID:
870900
•Concept ID:
C4025362
•
Anatomical Abnormality
Synonyms: Abnormality of the gastric mucosa; Abnormality of the mucous membrane layer of stomach
 
HPO: HP:0004295

Definition

An abnormality of the gastric mucous membrane. [from HPO]

Professional guidelines

PubMed

AGA Clinical Practice Update on Endoscopic Treatment of Barrett's Esophagus With Dysplasia and/or Early Cancer: Expert Review.
Sharma P, Shaheen NJ, Katzka D, Bergman JJGHM
Gastroenterology 2020 Feb;158(3):760-769. Epub 2019 Nov 12 doi: 10.1053/j.gastro.2019.09.051. PMID: 31730766
Oral lichen planus - Differential diagnoses, serum autoantibodies, hematinic deficiencies, and management.
Chiang CP, Yu-Fong Chang J, Wang YP, Wu YH, Lu SY, Sun A
J Formos Med Assoc 2018 Sep;117(9):756-765. Epub 2018 Feb 19 doi: 10.1016/j.jfma.2018.01.021. PMID: 29472048
Giant jejunoileal duplication: prenatal diagnosis and complete excision without intestinal resection.
Schwartz DL
J Pediatr Surg 1994 Sep;29(9):1291. doi: 10.1016/0022-3468(94)90861-3. PMID: 7807369

Recent clinical studies

Etiology

Helicobacter pylori-induced RASAL2 Through Activation of Nuclear Factor-κB Promotes Gastric Tumorigenesis via β-catenin Signaling Axis.
Cao L, Zhu S, Lu H, Soutto M, Bhat N, Chen Z, Peng D, Lin J, Lu J, Li P, Zheng C, Huang C, El-Rifai W
Gastroenterology 2022 May;162(6):1716-1731.e17. Epub 2022 Feb 5 doi: 10.1053/j.gastro.2022.01.046. PMID: 35134322Free PMC Article
Management of incidentally discovered unaffected Meckel's diverticulum - a review.
Żyluk A
Pol Przegl Chir 2019 Aug 12;91(6):41-46. doi: 10.5604/01.3001.0013.3400. PMID: 31849359
Clinical manifestations of chronic atrophic gastritis.
Rodriguez-Castro KI, Franceschi M, Noto A, Miraglia C, Nouvenne A, Leandro G, Meschi T, De' Angelis GL, Di Mario F
Acta Biomed 2018 Dec 17;89(8-S):88-92. doi: 10.23750/abm.v89i8-S.7921. PMID: 30561424Free PMC Article
Mediastinal foregut duplication cysts.
Rattan KN, Magu S, Rohilla S
Indian J Pediatr 2004 Jan;71(1):103-5. doi: 10.1007/BF02725668. PMID: 14979396
Emotion-related gastritis.
Goldberg SJ, Smith CL, Connell AM
Am J Gastroenterol 1976 Jan;65(1):41-5. PMID: 1274929

Diagnosis

Management of incidentally discovered unaffected Meckel's diverticulum - a review.
Żyluk A
Pol Przegl Chir 2019 Aug 12;91(6):41-46. doi: 10.5604/01.3001.0013.3400. PMID: 31849359
Clinical manifestations of chronic atrophic gastritis.
Rodriguez-Castro KI, Franceschi M, Noto A, Miraglia C, Nouvenne A, Leandro G, Meschi T, De' Angelis GL, Di Mario F
Acta Biomed 2018 Dec 17;89(8-S):88-92. doi: 10.23750/abm.v89i8-S.7921. PMID: 30561424Free PMC Article
A mobile Meckel!
El-Matary W, Roseman D, Lees G, Maguire C
Eur J Pediatr 2009 Dec;168(12):1525-7. Epub 2009 Feb 26 doi: 10.1007/s00431-009-0946-8. PMID: 19242720
Mediastinal foregut duplication cysts.
Rattan KN, Magu S, Rohilla S
Indian J Pediatr 2004 Jan;71(1):103-5. doi: 10.1007/BF02725668. PMID: 14979396
Watermelon stomach.
Park RH, Russell RI
Br J Surg 1991 Apr;78(4):395-6. doi: 10.1002/bjs.1800780405. PMID: 2032095

Therapy

AGA Clinical Practice Update on Endoscopic Treatment of Barrett's Esophagus With Dysplasia and/or Early Cancer: Expert Review.
Sharma P, Shaheen NJ, Katzka D, Bergman JJGHM
Gastroenterology 2020 Feb;158(3):760-769. Epub 2019 Nov 12 doi: 10.1053/j.gastro.2019.09.051. PMID: 31730766
Dyspepsia update.
Colin-Jones DG
Scand J Gastroenterol Suppl 1995;210:32-5. doi: 10.3109/00365529509090266. PMID: 8578202
Portal hypertensive gastropathy.
Triger DR
Baillieres Clin Gastroenterol 1992 Sep;6(3):481-95. doi: 10.1016/0950-3528(92)90034-c. PMID: 1421596
Pathogenesis and pathophysiology of duodenal ulcer.
Lam SK
Clin Gastroenterol 1984 May;13(2):447-72. PMID: 6378445
Diffuse varioliform gastritis.
Lambert R, André C, Moulinier B, Bugnon B
Digestion 1978;17(2):159-67. doi: 10.1159/000198106. PMID: 414953

Prognosis

Pathology and Clinical Relevance of Gastric Epithelial Dysplasia.
Ushiku T, Lauwers GY
Gastroenterol Clin North Am 2024 Mar;53(1):39-55. doi: 10.1016/j.gtc.2023.11.003. PMID: 38280750
Helicobacter pylori-induced RASAL2 Through Activation of Nuclear Factor-κB Promotes Gastric Tumorigenesis via β-catenin Signaling Axis.
Cao L, Zhu S, Lu H, Soutto M, Bhat N, Chen Z, Peng D, Lin J, Lu J, Li P, Zheng C, Huang C, El-Rifai W
Gastroenterology 2022 May;162(6):1716-1731.e17. Epub 2022 Feb 5 doi: 10.1053/j.gastro.2022.01.046. PMID: 35134322Free PMC Article
MALT lymphomas: pathogenesis can drive treatment.
Bertoni F, Coiffier B, Salles G, Stathis A, Traverse-Glehen A, Thieblemont C, Zucca E
Oncology (Williston Park) 2011 Nov 15;25(12):1134-42, 1147. PMID: 22229204
Mediastinal foregut duplication cysts.
Rattan KN, Magu S, Rohilla S
Indian J Pediatr 2004 Jan;71(1):103-5. doi: 10.1007/BF02725668. PMID: 14979396
Gastric and duodenal polyps in familial polyposis coli.
Ranzi T, Castagnone D, Velio P, Bianchi P, Polli EE
Gut 1981 May;22(5):363-7. doi: 10.1136/gut.22.5.363. PMID: 7250748Free PMC Article

Clinical prediction guides

Pathology and Clinical Relevance of Gastric Epithelial Dysplasia.
Ushiku T, Lauwers GY
Gastroenterol Clin North Am 2024 Mar;53(1):39-55. doi: 10.1016/j.gtc.2023.11.003. PMID: 38280750
The Dieulafoy's Lesion: An Update on Evaluation, Diagnosis, and Management.
Nguyen DC, Jackson CS
J Clin Gastroenterol 2015 Aug;49(7):541-9. doi: 10.1097/MCG.0000000000000321. PMID: 25887110
Electron microscopic study of association between Helicobacter pylori and gastric and duodenal mucosa.
Noach LA, Rolf TM, Tytgat GN
J Clin Pathol 1994 Aug;47(8):699-704. doi: 10.1136/jcp.47.8.699. PMID: 7962619Free PMC Article
Gastric and duodenal polyps in familial polyposis coli.
Ranzi T, Castagnone D, Velio P, Bianchi P, Polli EE
Gut 1981 May;22(5):363-7. doi: 10.1136/gut.22.5.363. PMID: 7250748Free PMC Article
Diffuse varioliform gastritis.
Lambert R, André C, Moulinier B, Bugnon B
Digestion 1978;17(2):159-67. doi: 10.1159/000198106. PMID: 414953

Recent systematic reviews

Histopathological Examination of 404 Sleeve Gastrectomy Specimens at a Large UK Center and Systematic Review of the Published Literature.
Briggs H, Nevins EJ, Musbahi A
Obes Surg 2025 Jan;35(1):263-270. Epub 2024 Dec 25 doi: 10.1007/s11695-024-07641-3. PMID: 39720968
Parietal cell/oncocytic gastric carcinoma: systematic review and first-time assessment of HER2 status in two new cases.
Mavroeidis VK, Gkegkes ID, Saffioti F, Kandilaris K, Alexiou K, Horti M, Economou N, Demonakou M
Ann R Coll Surg Engl 2020 Apr;102(4):300-307. Epub 2020 Jan 13 doi: 10.1308/rcsann.2019.0183. PMID: 31928359Free PMC Article

Supplemental Content

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