U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Bone-in-a-bone appearance of carpal bones

MedGen UID:
870941
•Concept ID:
C4025403
•
Finding
Synonym: Bone-in-a-bone appearance of wrist bones
 
HPO: HP:0004234

Definition

The bone-in-bone sign is a radiographic finding produced by increased sclerosis (abnormally dense bone) occurring intermittently with zones of relatively normal bone density. This term should be used to describe such a finding in the carpal bones. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBone-in-a-bone appearance of carpal bones

Professional guidelines

PubMed

A systematic review of postoperative hand therapy management of basal joint arthritis.
Wolfe T, Chu JY, Woods T, Lubahn JD
Clin Orthop Relat Res 2014 Apr;472(4):1190-7. doi: 10.1007/s11999-013-3285-z. PMID: 24249530Free PMC Article
Kienbock's disease: diagnosis and treatment.
Allan CH, Joshi A, Lichtman DM
J Am Acad Orthop Surg 2001 Mar-Apr;9(2):128-36. doi: 10.5435/00124635-200103000-00006. PMID: 11281636
Lunotriquetral instability: diagnosis and treatment.
Shin AY, Battaglia MJ, Bishop AT
J Am Acad Orthop Surg 2000 May-Jun;8(3):170-9. doi: 10.5435/00124635-200005000-00004. PMID: 10874224

Recent clinical studies

Etiology

The outcome of bone graft surgery for nonunion of fractures of the scaphoid.
Ammori MB, Elvey M, Mahmoud SS, Nicholls AJ, Robinson S, Rowan C, Spence S, Wade RG, Karantana A; British Society for Surgery of the Hand Scaphoid Nonunion Group, Davis TRC
J Hand Surg Eur Vol 2019 Sep;44(7):676-684. Epub 2019 May 20 doi: 10.1177/1753193419841278. PMID: 31109228Free PMC Article
Chondrosarcomas of the hands and feet: A case series and systematic review of the literature.
Fayad LM, Ahlawat S, Khan MS, McCarthy E
Eur J Radiol 2015 Oct;84(10):2004-12. Epub 2015 Jul 2 doi: 10.1016/j.ejrad.2015.06.026. PMID: 26189572
Silicone implants.
Kleinert JM, Lister GD
Hand Clin 1986 May;2(2):271-90. PMID: 2939096
Radiocarpal fracture--dislocation.
Schoenecker PL, Gilula LA, Shively RA, Manske PR
Clin Orthop Relat Res 1985 Jul-Aug;(197):237-44. PMID: 4017340
Lunotriquetral sprains.
Reagan DS, Linscheid RL, Dobyns JH
J Hand Surg Am 1984 Jul;9(4):502-14. doi: 10.1016/s0363-5023(84)80101-x. PMID: 6747234

Diagnosis

The Role of Wrist Arthroscopy in Kienbock Disease.
MacLean SBM, Kantar K, Bain GI, Lichtman DM
Hand Clin 2017 Nov;33(4):727-734. doi: 10.1016/j.hcl.2017.07.003. PMID: 28991584
Hook of the Hamate: The Spectrum of Often Missed Pathologic Findings.
Davis DL
AJR Am J Roentgenol 2017 Nov;209(5):1110-1118. Epub 2017 Aug 23 doi: 10.2214/AJR.17.18043. PMID: 28834449Free PMC Article
Dynamic high-resolution ultrasound of intrinsic and extrinsic ligaments of the wrist: How to make it simple.
Gitto S, Messina C, Mauri G, Aliprandi A, Sardanelli F, Sconfienza LM
Eur J Radiol 2017 Feb;87:20-35. Epub 2016 Dec 5 doi: 10.1016/j.ejrad.2016.12.002. PMID: 28065372
Kienböck's disease.
Beredjiklian PK
J Hand Surg Am 2009 Jan;34(1):167-75. doi: 10.1016/j.jhsa.2008.10.012. PMID: 19121745
Avascular necrosis of carpal bones.
Golimbu CN, Firooznia H, Rafii M
Magn Reson Imaging Clin N Am 1995 May;3(2):281-303. PMID: 7553023

Therapy

Preoperative Antibiotics in Wrist Arthroscopy.
Hoel RJ, Mittelsteadt MJ, Samborski SA, Bohn DC
J Hand Surg Am 2018 Nov;43(11):987-991.e1. Epub 2018 May 16 doi: 10.1016/j.jhsa.2018.03.040. PMID: 29778348
Endoscopic release for carpal tunnel syndrome.
Vasiliadis HS, Georgoulas P, Shrier I, Salanti G, Scholten RJ
Cochrane Database Syst Rev 2014 Jan 31;2014(1):CD008265. doi: 10.1002/14651858.CD008265.pub2. PMID: 24482073Free PMC Article
A systematic review of postoperative hand therapy management of basal joint arthritis.
Wolfe T, Chu JY, Woods T, Lubahn JD
Clin Orthop Relat Res 2014 Apr;472(4):1190-7. doi: 10.1007/s11999-013-3285-z. PMID: 24249530Free PMC Article
Surgical treatment of trapeziometacarpal joint arthritis: a historical perspective.
Hentz VR
Clin Orthop Relat Res 2014 Apr;472(4):1184-9. doi: 10.1007/s11999-013-3374-z. PMID: 24214823Free PMC Article
Silicone implants.
Kleinert JM, Lister GD
Hand Clin 1986 May;2(2):271-90. PMID: 2939096

Prognosis

Computer Modelling of Wrist Biomechanics: Translation into Specific Tasks and Injuries.
Sandow MJ
Curr Rheumatol Rev 2020;16(3):178-183. doi: 10.2174/1573397115666190119095311. PMID: 30659546
Infantile and juvenile lunatomalacia.
Irisarri C, Kalb K, Ribak S
J Hand Surg Eur Vol 2010 Sep;35(7):544-8. Epub 2010 Mar 17 doi: 10.1177/1753193410364913. PMID: 20237187
Avascular necrosis of carpal bones.
Golimbu CN, Firooznia H, Rafii M
Magn Reson Imaging Clin N Am 1995 May;3(2):281-303. PMID: 7553023
Radiocarpal fracture--dislocation.
Schoenecker PL, Gilula LA, Shively RA, Manske PR
Clin Orthop Relat Res 1985 Jul-Aug;(197):237-44. PMID: 4017340
Lunotriquetral sprains.
Reagan DS, Linscheid RL, Dobyns JH
J Hand Surg Am 1984 Jul;9(4):502-14. doi: 10.1016/s0363-5023(84)80101-x. PMID: 6747234

Clinical prediction guides

Lunate biomechanics: application to Kienböck's disease and its treatment.
Camus EJ, Van Overstraeten L, Schuind F
Hand Surg Rehabil 2021 Apr;40(2):117-125. Epub 2020 Dec 10 doi: 10.1016/j.hansur.2020.10.017. PMID: 33309792
Computer Modelling of Wrist Biomechanics: Translation into Specific Tasks and Injuries.
Sandow MJ
Curr Rheumatol Rev 2020;16(3):178-183. doi: 10.2174/1573397115666190119095311. PMID: 30659546
Radial longitudinal deficiency. Analysis of clinical and radiological results.
Vergara-Amador E, López Rincón L, Herrera Rodríguez S
Rev Esp Cir Ortop Traumatol (Engl Ed) 2019 May-Jun;63(3):217-226. Epub 2018 Dec 9 doi: 10.1016/j.recot.2018.10.004. PMID: 30541698
Carpal bone cysts: MRI, gross pathology, and histology correlation in cadavers.
Sanal HT, Chen L, Haghighi P, Trudell DJ, Resnick DL
Diagn Interv Radiol 2014 Nov;20(6):503-6. doi: 10.5152/dir.2014.14209. PMID: 25205027Free PMC Article
Radial shortening.
Weiss AP
Hand Clin 1993 Aug;9(3):475-82. PMID: 8408257

Recent systematic reviews

Outcomes of acute perilunate injuries-a systematic review.
Liechti R, Merky DN, Grobbelaar AO, van de Wall BJM, Vögelin E, Hirsiger S
Eur J Trauma Emerg Surg 2023 Oct;49(5):2071-2084. Epub 2023 Feb 7 doi: 10.1007/s00068-023-02222-y. PMID: 36750472
Chondrosarcomas of the hands and feet: A case series and systematic review of the literature.
Fayad LM, Ahlawat S, Khan MS, McCarthy E
Eur J Radiol 2015 Oct;84(10):2004-12. Epub 2015 Jul 2 doi: 10.1016/j.ejrad.2015.06.026. PMID: 26189572
Endoscopic release for carpal tunnel syndrome.
Vasiliadis HS, Georgoulas P, Shrier I, Salanti G, Scholten RJ
Cochrane Database Syst Rev 2014 Jan 31;2014(1):CD008265. doi: 10.1002/14651858.CD008265.pub2. PMID: 24482073Free PMC Article
A systematic review of postoperative hand therapy management of basal joint arthritis.
Wolfe T, Chu JY, Woods T, Lubahn JD
Clin Orthop Relat Res 2014 Apr;472(4):1190-7. doi: 10.1007/s11999-013-3285-z. PMID: 24249530Free PMC Article
Osseous and ligamentous scaphoid anatomy: Part I. A systematic literature review highlighting controversies.
Buijze GA, Lozano-Calderon SA, Strackee SD, Blankevoort L, Jupiter JB
J Hand Surg Am 2011 Dec;36(12):1926-35. Epub 2011 Nov 3 doi: 10.1016/j.jhsa.2011.09.012. PMID: 22051230

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...