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Abnormality of skull ossification

MedGen UID:
871207
•Concept ID:
C4025686
•
Finding
Synonyms: Abnormality of bone calcification of calvarium; Abnormality of bone calcification of cranium; Abnormality of bone calcification of skull; Abnormality of bone formation of calvarium; Abnormality of bone formation of cranium; Abnormality of bone mineralization of calvarium; Abnormality of bone mineralization of cranium; Abnormality of bone mineralization of skull; Abnormality of ossification of calvarium; Abnormality of ossification of cranium; Abnormality of skull bone formation
 
HPO: HP:0002703

Definition

An abnormality of the process of ossification of the skull. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of skull ossification

Professional guidelines

PubMed

The etiology, clinical features, and treatment options of hemifacial microsomia.
Luo S, Sun H, Bian Q, Liu Z, Wang X
Oral Dis 2023 Sep;29(6):2449-2462. Epub 2023 Mar 13 doi: 10.1111/odi.14508. PMID: 36648381
Nonsurgical Orthodontic Airway Plate Treatment for Newborns With Robin Sequence.
Choo H, Khosla RK, Meister KD, Wan DC, Lin HC, Feczko R, Bruckman K, Hopkins E, Truong MT, Lorenz HP
Cleft Palate Craniofac J 2022 Mar;59(3):403-410. Epub 2021 Apr 13 doi: 10.1177/10556656211007689. PMID: 33845627
Reprint of-Differential diagnosis: Trepanation.
Verano JW
Int J Paleopathol 2017 Dec;19:111-118. Epub 2017 Mar 28 doi: 10.1016/j.ijpp.2017.03.004. PMID: 29198392

Recent clinical studies

Etiology

Distraction osteogenesis in craniosynostosis.
Sandhaus H, Johnson MD
Curr Opin Otolaryngol Head Neck Surg 2021 Aug 1;29(4):304-313. doi: 10.1097/MOO.0000000000000724. PMID: 34183561
Orthognathic Surgery for Patients with Cleft Lip and Palate.
Roy AA, Rtshiladze MA, Stevens K, Phillips J
Clin Plast Surg 2019 Apr;46(2):157-171. Epub 2019 Feb 6 doi: 10.1016/j.cps.2018.11.002. PMID: 30851748
Unusual Craniofacial Distraction.
Greig AVH, Cutting CB, Levine J, Grayson B, McCarthy JG
J Craniofac Surg 2018 May;29(3):698-702. doi: 10.1097/SCS.0000000000004277. PMID: 29303863
Classification and Current Management of Inner Ear Malformations.
Sennaroğlu L, Bajin MD
Balkan Med J 2017 Sep 29;34(5):397-411. Epub 2017 Aug 25 doi: 10.4274/balkanmedj.2017.0367. PMID: 28840850Free PMC Article
Genetic disorders and bone affecting the craniofacial skeleton.
Chacon GE, Ugalde CM, Jabero MF
Oral Maxillofac Surg Clin North Am 2007 Nov;19(4):467-74, v. doi: 10.1016/j.coms.2007.08.001. PMID: 18088898

Diagnosis

Eagle's Syndrome.
Miyagawa S, Ono R, Ito R, Kitagawa I
Intern Med 2022 Aug 15;61(16):2553. Epub 2022 Feb 1 doi: 10.2169/internalmedicine.9017-21. PMID: 35110494Free PMC Article
Stylohyoid Syndrome.
Willett GM, Walker TF, Norton NS
J Orthop Sports Phys Ther 2019 Aug;49(8):621. doi: 10.2519/jospt.2019.8759. PMID: 31366296
Pierre Robin Sequence.
Hsieh ST, Woo AS
Clin Plast Surg 2019 Apr;46(2):249-259. Epub 2019 Feb 8 doi: 10.1016/j.cps.2018.11.010. PMID: 30851756
Eagle syndrome: A comprehensive review.
Badhey A, Jategaonkar A, Anglin Kovacs AJ, Kadakia S, De Deyn PP, Ducic Y, Schantz S, Shin E
Clin Neurol Neurosurg 2017 Aug;159:34-38. Epub 2017 May 6 doi: 10.1016/j.clineuro.2017.04.021. PMID: 28527976
Craniofacial distraction osteogenesis.
Winters R, Tatum SA
Facial Plast Surg Clin North Am 2014 Nov;22(4):653-64. Epub 2014 Nov 8 doi: 10.1016/j.fsc.2014.08.003. PMID: 25444735

Therapy

Orthognathic Surgery for Patients with Cleft Lip and Palate.
Roy AA, Rtshiladze MA, Stevens K, Phillips J
Clin Plast Surg 2019 Apr;46(2):157-171. Epub 2019 Feb 6 doi: 10.1016/j.cps.2018.11.002. PMID: 30851748
Surgical and orthodontic treatment of a fused maxillary central incisor and supernumerary tooth.
Finkelstein T, Shapira Y, Bechor N, Shpack N
J Clin Orthod 2014 Oct;48(10):654-8. PMID: 25416343
Speedy orthodontics: a case report.
Krishnan KV, Kumaran NK, Rajasigamani K, Vijay V, Rajaram RS, Bhaskar V
Orthodontics (Chic.) 2013;14(1):e96-e100. doi: 10.11607/ortho.911. PMID: 23646344
Mandibular distraction osteogenesis in the micrognathic neonate: a review for neonatologists and pediatricians.
Hong P, Bezuhly M
Pediatr Neonatol 2013 Jun;54(3):153-60. Epub 2013 Feb 1 doi: 10.1016/j.pedneo.2012.11.018. PMID: 23597538
The spine in osteogenesis imperfecta: a review of treatment.
Oppenheim WL
Connect Tissue Res 1995;31(4):S59-63. doi: 10.3109/03008209509116836. PMID: 15612384

Prognosis

Human genetics and molecular genomics of Chiari malformation type 1.
Mekbib KY, Muñoz W, Allington G, McGee S, Mehta NH, Shofi JP, Fortes C, Le HT, Nelson-Williams C, Nanda P, Dennis E, Kundishora AJ, Khanna A, Smith H, Ocken J, Greenberg ABW, Wu R, Moreno-De-Luca A, DeSpenza T Jr, Zhao S, Marlier A, Jin SC, Alper SL, Butler WE, Kahle KT
Trends Mol Med 2023 Dec;29(12):1059-1075. Epub 2023 Oct 4 doi: 10.1016/j.molmed.2023.08.013. PMID: 37802664
Management of eagle syndrome.
Sharifi A, Kouhi A
Curr Opin Otolaryngol Head Neck Surg 2023 Aug 1;31(4):276-280. Epub 2023 Jun 8 doi: 10.1097/MOO.0000000000000903. PMID: 37387673
Cleft Lip and Palate: LeFort I Distraction with Halo and Hybrid Internal Maxillary Distractors.
Figueroa AA, Figueroa AD, Burton RG, Tragos C
Clin Plast Surg 2021 Jul;48(3):391-405. Epub 2021 May 8 doi: 10.1016/j.cps.2021.02.002. PMID: 34051893
Orthodontic and Surgical Principles for Distraction Osteogenesis in Children with Pierre-Robin Sequence.
Yen S, Gaal A, Smith KS
Oral Maxillofac Surg Clin North Am 2020 May;32(2):283-295. doi: 10.1016/j.coms.2020.01.012. PMID: 32247440
Glossoptosis.
Schweiger C, Manica D, Kuhl G
Semin Pediatr Surg 2016 Jun;25(3):123-7. Epub 2016 Feb 18 doi: 10.1053/j.sempedsurg.2016.02.002. PMID: 27301596

Clinical prediction guides

Human genetics and molecular genomics of Chiari malformation type 1.
Mekbib KY, Muñoz W, Allington G, McGee S, Mehta NH, Shofi JP, Fortes C, Le HT, Nelson-Williams C, Nanda P, Dennis E, Kundishora AJ, Khanna A, Smith H, Ocken J, Greenberg ABW, Wu R, Moreno-De-Luca A, DeSpenza T Jr, Zhao S, Marlier A, Jin SC, Alper SL, Butler WE, Kahle KT
Trends Mol Med 2023 Dec;29(12):1059-1075. Epub 2023 Oct 4 doi: 10.1016/j.molmed.2023.08.013. PMID: 37802664
Cleft Lip and Palate: LeFort I Distraction with Halo and Hybrid Internal Maxillary Distractors.
Figueroa AA, Figueroa AD, Burton RG, Tragos C
Clin Plast Surg 2021 Jul;48(3):391-405. Epub 2021 May 8 doi: 10.1016/j.cps.2021.02.002. PMID: 34051893
Orthodontic and Surgical Principles for Distraction Osteogenesis in Children with Pierre-Robin Sequence.
Yen S, Gaal A, Smith KS
Oral Maxillofac Surg Clin North Am 2020 May;32(2):283-295. doi: 10.1016/j.coms.2020.01.012. PMID: 32247440
Classification and Current Management of Inner Ear Malformations.
Sennaroğlu L, Bajin MD
Balkan Med J 2017 Sep 29;34(5):397-411. Epub 2017 Aug 25 doi: 10.4274/balkanmedj.2017.0367. PMID: 28840850Free PMC Article
Renal tubular dysgenesis.
Gubler MC
Pediatr Nephrol 2014 Jan;29(1):51-9. Epub 2013 May 1 doi: 10.1007/s00467-013-2480-1. PMID: 23636579

Recent systematic reviews

Neurological phenotypes and treatment outcomes in Eagle syndrome: systematic review and meta-analysis.
Hassani M, Grønlund EW, Albrechtsen SS, Kondziella D
PeerJ 2024;12:e17423. Epub 2024 Jun 26 doi: 10.7717/peerj.17423. PMID: 38948209Free PMC Article
An evaluation of mandibular canal variations: a systematic review and meta-analysis.
Asghar A, Priya A, Ravi KS, Iwanaga J, Tubbs RS, Naaz S, Panchal P
Anat Sci Int 2023 Mar;98(2):176-184. Epub 2022 Aug 29 doi: 10.1007/s12565-022-00682-7. PMID: 36038792
Prevalence and features of elongated styloid process on imaging studies: a systematic review and meta-analysis.
Nogueira-Reis F, de Oliveira Reis L, Fontenele RC, Freitas DQ, Tabchoury CPM
Clin Oral Investig 2022 Feb;26(2):1199-1215. Epub 2021 Nov 20 doi: 10.1007/s00784-021-04285-w. PMID: 34800204
Complications of mandibular distraction osteogenesis for developmental deformities: a systematic review of the literature.
Verlinden CR, van de Vijfeijken SE, Tuinzing DB, Jansma EP, Becking AG, Swennen GR
Int J Oral Maxillofac Surg 2015 Jan;44(1):44-9. Epub 2014 Oct 29 doi: 10.1016/j.ijom.2014.09.007. PMID: 25442740
Complications of frontofacial advancement.
Dunaway DJ, Britto JA, Abela C, Evans RD, Jeelani NU
Childs Nerv Syst 2012 Sep;28(9):1571-6. Epub 2012 Aug 8 doi: 10.1007/s00381-012-1804-y. PMID: 22872275

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