Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Abnormality of subcutaneous fat tissue

MedGen UID:: 871325
•Concept ID:: C4025813
•: Anatomical Abnormality

Synonym:	Abnormality of fatty tissue below the skin

HPO:	HP:0001001

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormality of subcutaneous fat tissue

Phenotypic abnormality
- Abnormality of the integument
  - Abnormality of the skin
    - Abnormal skin morphology
      - Generalized abnormality of skin
        Abnormality of subcutaneous fat tissue
        Abnormal subcutaneous fat tissue distribution
        Dorsocervical fat pad
        Superficial blush-like subcutaneous fatty lesions
        Yellow subcutaneous tissue covered by thin, scaly skin

Professional guidelines

PubMed

Cervical Necrotizing Fasciitis, Diagnosis and Treatment of a Rare Life-Threatening Infection.

Hua J, Friedlander P
Ear Nose Throat J 2023 Mar;102(3):NP109-NP113. Epub 2021 Feb 11 doi: 10.1177/0145561321991341. PMID: 33570428

Ultrasound criteria for lipedema diagnosis.

Amato ACM, Saucedo DZ, Santos KDS, Benitti DA
Phlebology 2021 Sep;36(8):651-658. Epub 2021 Apr 15 doi: 10.1177/02683555211002340. PMID: 33853452

Physiotherapy and rehabilitation applications in lipedema management: A literature review.

Esmer M, Schingale FJ, Unal D, Yazıcı MV, Güzel NA
Lymphology 2020;53(2):88-95. PMID: 33190432

See all (22)

Recent clinical studies

Etiology

Ultrasound criteria for lipedema diagnosis.

Amato ACM, Saucedo DZ, Santos KDS, Benitti DA
Phlebology 2021 Sep;36(8):651-658. Epub 2021 Apr 15 doi: 10.1177/02683555211002340. PMID: 33853452

Obesity, Adipose Tissue and Vascular Dysfunction.

Koenen M, Hill MA, Cohen P, Sowers JR
Circ Res 2021 Apr 2;128(7):951-968. Epub 2021 Apr 1 doi: 10.1161/CIRCRESAHA.121.318093. PMID: 33793327 Free PMC Article

Metabolically Healthy Obesity.

Blüher M
Endocr Rev 2020 May 1;41(3) doi: 10.1210/endrev/bnaa004. PMID: 32128581 Free PMC Article

Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications.

Longo M, Zatterale F, Naderi J, Parrillo L, Formisano P, Raciti GA, Beguinot F, Miele C
Int J Mol Sci 2019 May 13;20(9) doi: 10.3390/ijms20092358. PMID: 31085992 Free PMC Article

Lipedema: friend and foe.

Torre YS, Wadeea R, Rosas V, Herbst KL
Horm Mol Biol Clin Investig 2018 Mar 9;33(1) doi: 10.1515/hmbci-2017-0076. PMID: 29522416 Free PMC Article

See all (382)

Diagnosis

Ultrasound criteria for lipedema diagnosis.

Amato ACM, Saucedo DZ, Santos KDS, Benitti DA
Phlebology 2021 Sep;36(8):651-658. Epub 2021 Apr 15 doi: 10.1177/02683555211002340. PMID: 33853452

Metabolically Healthy Obesity.

Blüher M
Endocr Rev 2020 May 1;41(3) doi: 10.1210/endrev/bnaa004. PMID: 32128581 Free PMC Article

Lipedema: friend and foe.

Torre YS, Wadeea R, Rosas V, Herbst KL
Horm Mol Biol Clin Investig 2018 Mar 9;33(1) doi: 10.1515/hmbci-2017-0076. PMID: 29522416 Free PMC Article

Hibernoma.

Klevos G, Jose J, Pretell-Mazzini J, Conway S
Am J Orthop (Belle Mead NJ) 2015 Jun;44(6):284-7. PMID: 26046999

Panniculitis in children.

Grassi S, Borroni RG, Brazzelli V
G Ital Dermatol Venereol 2013 Aug;148(4):371-85. PMID: 23900159

See all (321)

Therapy

Light-responsive adipose-hypothalamus axis controls metabolic regulation.

Tsuji T, Tolstikov V, Zhang Y, Huang TL, Camara H, Halpin M, Narain NR, Yau KW, Lynes MD, Kiebish MA, Tseng YH
Nat Commun 2024 Aug 8;15(1):6768. doi: 10.1038/s41467-024-50866-0. PMID: 39117652 Free PMC Article

Once-weekly semaglutide in people with HIV-associated lipohypertrophy: a randomised, double-blind, placebo-controlled phase 2b single-centre clinical trial.

Eckard AR, Wu Q, Sattar A, Ansari-Gilani K, Labbato D, Foster T, Fletcher AA, Adekunle RO, McComsey GA
Lancet Diabetes Endocrinol 2024 Aug;12(8):523-534. Epub 2024 Jul 1 doi: 10.1016/S2213-8587(24)00150-5. PMID: 38964353 Free PMC Article

Mitochondrial respiration is decreased in visceral but not subcutaneous adipose tissue in obese individuals with fatty liver disease.

Pafili K, Kahl S, Mastrototaro L, Strassburger K, Pesta D, Herder C, Pützer J, Dewidar B, Hendlinger M, Granata C, Saatmann N, Yavas A, Gancheva S, Heilmann G, Esposito I, Schlensak M, Roden M
J Hepatol 2022 Dec;77(6):1504-1514. Epub 2022 Aug 19 doi: 10.1016/j.jhep.2022.08.010. PMID: 35988689

Panniculitis in children.

Grassi S, Borroni RG, Brazzelli V
G Ital Dermatol Venereol 2013 Aug;148(4):371-85. PMID: 23900159

Subcutaneous fat necrosis of the newborn.

Weary PE, Graham GF, Selden RF Jr
South Med J 1966 Aug;59(8):960-5. doi: 10.1097/00007611-196608000-00018. PMID: 5917108

See all (143)

Prognosis

AI-based CT Body Composition Identifies Myosteatosis as Key Mortality Predictor in Asymptomatic Adults.

Nachit M, Horsmans Y, Summers RM, Leclercq IA, Pickhardt PJ
Radiology 2023 Jun;307(5):e222008. Epub 2023 May 16 doi: 10.1148/radiol.222008. PMID: 37191484 Free PMC Article

Abnormal Peri-organ-Intra-organ Fat (APIFat) and Rheumatoid Arthritis: An Under-investigated Link for Increased Cardiovascular Risk?

Katsiki N, Mikhailidis DP, Mantzoros C
Curr Vasc Pharmacol 2020;18(3):249-253. doi: 10.2174/1570161117999190802150857. PMID: 32340599

Pancreatic panniculitis.

Rongioletti F, Caputo V
G Ital Dermatol Venereol 2013 Aug;148(4):419-25. PMID: 23900163

Panniculitis in children.

Grassi S, Borroni RG, Brazzelli V
G Ital Dermatol Venereol 2013 Aug;148(4):371-85. PMID: 23900159

Lipomatous tumors.

Weiss SW
Monogr Pathol 1996;38:207-39. PMID: 8744279

See all (164)

Clinical prediction guides

Once-weekly semaglutide in people with HIV-associated lipohypertrophy: a randomised, double-blind, placebo-controlled phase 2b single-centre clinical trial.

AI-based CT Body Composition Identifies Myosteatosis as Key Mortality Predictor in Asymptomatic Adults.

Nachit M, Horsmans Y, Summers RM, Leclercq IA, Pickhardt PJ
Radiology 2023 Jun;307(5):e222008. Epub 2023 May 16 doi: 10.1148/radiol.222008. PMID: 37191484 Free PMC Article

Physiological and Lifestyle Traits of Metabolic Dysfunction in the Absence of Obesity.

Klitgaard HB, Kilbak JH, Nozawa EA, Seidel AV, Magkos F
Curr Diab Rep 2020 Mar 31;20(6):17. doi: 10.1007/s11892-020-01302-2. PMID: 32232577

Metabolically Healthy Obesity.

Blüher M
Endocr Rev 2020 May 1;41(3) doi: 10.1210/endrev/bnaa004. PMID: 32128581 Free PMC Article

The Current State of Fat Grafting: A Review of Harvesting, Processing, and Injection Techniques.

Strong AL, Cederna PS, Rubin JP, Coleman SR, Levi B
Plast Reconstr Surg 2015 Oct;136(4):897-912. doi: 10.1097/PRS.0000000000001590. PMID: 26086386 Free PMC Article

See all (243)

Recent systematic reviews

Influence of glucagon-like peptide-1 receptor agonists on fat accumulation in patients with diabetes mellitus and non-alcoholic fatty liver disease or obesity: A systematic review and meta-analysis of randomized control trials.

Xie W, Hong Z, Li B, Huang B, Dong S, Cai Y, Ruan L, Xu Q, Mou L, Zhang Y
J Diabetes Complications 2024 Jun;38(6):108743. Epub 2024 Apr 4 doi: 10.1016/j.jdiacomp.2024.108743. PMID: 38688179

Imaging-Based Body Fat Distribution in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.

Zhu S, Li Z, Hu C, Sun F, Wang C, Yuan H, Li Y
Front Endocrinol (Lausanne) 2021;12:697223. Epub 2021 Sep 9 doi: 10.3389/fendo.2021.697223. PMID: 34566888 Free PMC Article

Subcutaneous fat necrosis of the newborn and associated hypercalcemia: A systematic review of the literature.

Stefanko NS, Drolet BA
Pediatr Dermatol 2019 Jan;36(1):24-30. Epub 2018 Sep 6 doi: 10.1111/pde.13640. PMID: 30187956

Adipofascial Flaps With Acellular Dermal Matrix Compared With Myocutaneous Flap Reconstruction in Lumbar Myelomeningocele Defects.

Pourtaheri N, Wang D, Calva D, Chopra K, Kumar AR
J Craniofac Surg 2018 Jul;29(5):1137-1142. doi: 10.1097/SCS.0000000000004598. PMID: 29750727

See all (4)

MedGen

National Center for Biotechnology Information

Send to:

Abnormality of subcutaneous fat tissue

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

Related information

Recent activity