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Malignant dermis tumor

MedGen UID:
87564
•Concept ID:
C0346811
•
Neoplastic Process
Synonyms: cancer of dermis; dermis cancer; Malignant Dermal Neoplasm; malignant dermal neoplasm; Malignant Dermis Neoplasm; malignant dermis neoplasm; Malignant Dermis Tumor; malignant dermis tumor; Malignant Neoplasm of Dermis; malignant neoplasm of dermis; Malignant Neoplasm of the Dermis; malignant neoplasm of the dermis; Malignant tumor of dermis; Malignant Tumor of Dermis; malignant tumor of dermis; Malignant Tumor of the Dermis; malignant tumor of the dermis; malignant tumour of dermis; malignant tumour of the dermis
SNOMED CT: Malignant tumor of dermis (255096006)
 
Monarch Initiative: MONDO:0003363

Definition

A malignancy that affects the dermis. [from NCI]

Professional guidelines

PubMed

Current Management and Treatment of Extramammary Paget's Disease.
Hashimoto H, Ito T
Curr Treat Options Oncol 2022 Jun;23(6):818-830. Epub 2022 Apr 4 doi: 10.1007/s11864-021-00923-3. PMID: 35377101
Dermoscopic Criteria, Histopathological Correlates and Genetic Findings of Thin Melanoma on Non-Volar Skin.
Massone C, Hofman-Wellenhof R, Chiodi S, Sola S
Genes (Basel) 2021 Aug 23;12(8) doi: 10.3390/genes12081288. PMID: 34440462Free PMC Article
Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder-clinical and histopathologic features, differential diagnosis, and treatment.
Gru AA, Wick MR, Eid M
Semin Cutan Med Surg 2018 Mar;37(1):39-48. doi: 10.12788/j.sder.2018.006. PMID: 29719019

Recent clinical studies

Etiology

Prepectoral Breast Reconstruction.
Graziano FD, Lu J, Sbitany H
Clin Plast Surg 2023 Apr;50(2):235-242. Epub 2023 Jan 2 doi: 10.1016/j.cps.2022.09.004. PMID: 36813401
Dermatofibrosarcoma Protuberans in Children.
Sleiwah A, Wright TC, Chapman T, Dangoor A, Maggiani F, Clancy R
Curr Treat Options Oncol 2022 Jun;23(6):843-854. Epub 2022 Apr 8 doi: 10.1007/s11864-022-00979-9. PMID: 35394606
Neutrophilic dermatoses: Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease.
Nelson CA, Stephen S, Ashchyan HJ, James WD, Micheletti RG, Rosenbach M
J Am Acad Dermatol 2018 Dec;79(6):987-1006. Epub 2018 Apr 11 doi: 10.1016/j.jaad.2017.11.064. PMID: 29653210
Soft Tissue Tumors of Uncertain Histogenesis: A Review for Dermatopathologists.
Buehler D, Weisman P
Clin Lab Med 2017 Sep;37(3):647-671. doi: 10.1016/j.cll.2017.06.005. PMID: 28802505
Extraskeletal osteosarcoma.
Chung EB, Enzinger FM
Cancer 1987 Sep 1;60(5):1132-42. doi: 10.1002/1097-0142(19870901)60:5<1132::aid-cncr2820600536>3.0.co;2-l. PMID: 3475157

Diagnosis

Neutrophilic dermatoses: Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease.
Nelson CA, Stephen S, Ashchyan HJ, James WD, Micheletti RG, Rosenbach M
J Am Acad Dermatol 2018 Dec;79(6):987-1006. Epub 2018 Apr 11 doi: 10.1016/j.jaad.2017.11.064. PMID: 29653210
Peripheral nerve sheath tumors of the breast.
Charu V, Cimino-Mathews A
Semin Diagn Pathol 2017 Sep;34(5):420-426. Epub 2017 May 27 doi: 10.1053/j.semdp.2017.05.011. PMID: 28647116
Cutaneous Malignant Peripheral Nerve Sheath Tumor.
Luzar B, Falconieri G
Surg Pathol Clin 2017 Jun;10(2):337-343. Epub 2017 Mar 14 doi: 10.1016/j.path.2017.01.008. PMID: 28477884
The grenz zone.
Abbas O, Mahalingam M
Am J Dermatopathol 2013 Feb;35(1):83-91. doi: 10.1097/DAD.0b013e31824feb4e. PMID: 23348142
Onycholemmal carcinoma.
Alessi E, Coggi A, Gianotti R, Parafioriti A, Berti E
Am J Dermatopathol 2004 Oct;26(5):397-402. doi: 10.1097/00000372-200410000-00010. PMID: 15365373

Therapy

Neutrophilic dermatoses: Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease.
Nelson CA, Stephen S, Ashchyan HJ, James WD, Micheletti RG, Rosenbach M
J Am Acad Dermatol 2018 Dec;79(6):987-1006. Epub 2018 Apr 11 doi: 10.1016/j.jaad.2017.11.064. PMID: 29653210
Post-mastectomy breast reconstruction.
Thiruchelvam PT, McNeill F, Jallali N, Harris P, Hogben K
BMJ 2013 Oct 15;347:f5903. doi: 10.1136/bmj.f5903. PMID: 24128977
Tattoos, inks, and cancer.
Kluger N, Koljonen V
Lancet Oncol 2012 Apr;13(4):e161-8. Epub 2012 Mar 30 doi: 10.1016/S1470-2045(11)70340-0. PMID: 22469126
Eccrine porocarcinoma.
Brown CW Jr, Dy LC
Dermatol Ther 2008 Nov-Dec;21(6):433-8. doi: 10.1111/j.1529-8019.2008.00243.x. PMID: 19076620
Cutaneous desmoplastic melanoma.
Busam KJ
Adv Anat Pathol 2005 Mar;12(2):92-102. doi: 10.1097/01.pap.0000155071.86944.a6. PMID: 15731577

Prognosis

Peripheral nerve sheath tumors of the breast.
Charu V, Cimino-Mathews A
Semin Diagn Pathol 2017 Sep;34(5):420-426. Epub 2017 May 27 doi: 10.1053/j.semdp.2017.05.011. PMID: 28647116
The grenz zone.
Abbas O, Mahalingam M
Am J Dermatopathol 2013 Feb;35(1):83-91. doi: 10.1097/DAD.0b013e31824feb4e. PMID: 23348142
Thin melanoma.
Elder DE
Arch Pathol Lab Med 2011 Mar;135(3):342-6. doi: 10.5858/2009-0479-RA.1. PMID: 21366458
Chordoma cutis.
Rubin AI, Bagel J, Niedt G
J Am Acad Dermatol 2005 May;52(5 Suppl 1):S105-8. doi: 10.1016/j.jaad.2004.07.055. PMID: 15858504
Cutaneous desmoplastic melanoma.
Busam KJ
Adv Anat Pathol 2005 Mar;12(2):92-102. doi: 10.1097/01.pap.0000155071.86944.a6. PMID: 15731577

Clinical prediction guides

Attempting to Solve the Pigmented Epithelioid Melanocytoma (PEM) Conundrum: PRKAR1A Inactivation Can Occur in Different Genetic Backgrounds (Common, Blue, and Spitz Subgroups) With Variation in Their Clinicopathologic Characteristics.
de la Fouchardiere A, Tirode F, Castillo C, Buisson A, Boivin F, Macagno N, Pissaloux D
Am J Surg Pathol 2022 Aug 1;46(8):1106-1115. Epub 2022 Mar 22 doi: 10.1097/PAS.0000000000001888. PMID: 35319526
Peripheral nerve sheath tumors of the breast.
Charu V, Cimino-Mathews A
Semin Diagn Pathol 2017 Sep;34(5):420-426. Epub 2017 May 27 doi: 10.1053/j.semdp.2017.05.011. PMID: 28647116
The grenz zone.
Abbas O, Mahalingam M
Am J Dermatopathol 2013 Feb;35(1):83-91. doi: 10.1097/DAD.0b013e31824feb4e. PMID: 23348142
Intravascular schwannoma.
Gaudi S, Mills O, Goyette EF, Morgan MB
Am J Dermatopathol 2011 Dec;33(8):850-4. doi: 10.1097/DAD.0b013e3181f5df90. PMID: 22042258
Onycholemmal carcinoma.
Alessi E, Coggi A, Gianotti R, Parafioriti A, Berti E
Am J Dermatopathol 2004 Oct;26(5):397-402. doi: 10.1097/00000372-200410000-00010. PMID: 15365373

Recent systematic reviews

Do we need acellular dermal matrix in prepectoral breast reconstruction? A systematic review and meta-analysis.
Nolan IT, Farajzadeh MM, Boyd CJ, Bekisz JM, Gibson EG, Salibian AA
J Plast Reconstr Aesthet Surg 2023 Nov;86:251-260. Epub 2023 Sep 21 doi: 10.1016/j.bjps.2023.09.042. PMID: 37793198
Laser Treatment Monitoring with Reflectance Confocal Microscopy.
Guida S, Longo C, Amato S, Rossi AM, Manfredini M, Ciardo S, Spadafora M, Nisticò SP, Mercuri SR, Rongioletti F, Zerbinati N, Pellacani G
Medicina (Kaunas) 2023 May 28;59(6) doi: 10.3390/medicina59061039. PMID: 37374244Free PMC Article
Dermatofibrosarcoma protuberans of the scalp: Surgical management in a multicentric series of 11 cases and systematic review of the literature.
Kuhlmann C, Ehrl D, Taha S, Wachtel N, Schmid A, Bronsert P, Zeller J, Giunta RE, Eisenhardt SU, Braig D
Surgery 2023 Jun;173(6):1463-1475. Epub 2023 Apr 1 doi: 10.1016/j.surg.2023.02.026. PMID: 37012145
Benefits and risks with acellular dermal matrix (ADM) and mesh support in immediate breast reconstruction: a systematic review and meta-analysis.
Hallberg H, Rafnsdottir S, Selvaggi G, Strandell A, Samuelsson O, Stadig I, Svanberg T, Hansson E, Lewin R
J Plast Surg Hand Surg 2018 Jun;52(3):130-147. Epub 2018 Jan 10 doi: 10.1080/2000656X.2017.1419141. PMID: 29320921
Diffuse melanosis cutis: a systematic review of the literature.
Sebaratnam DF, Venugopal SS, Frew JW, McMillan JR, Finkelstein ER, Martin LK, Murrell DF
J Am Acad Dermatol 2013 Mar;68(3):482-8. Epub 2012 Dec 6 doi: 10.1016/j.jaad.2012.08.018. PMID: 23219556

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