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Gastric lymphoma

MedGen UID:
87603
•Concept ID:
C0349532
•
Neoplastic Process
Synonym: Familial primary gastric lymphoma
SNOMED CT: Gastric lymphoma (276811008); Lymphoma of stomach (276811008)
 
HPO: HP:0045038
Monarch Initiative: MONDO:0001059

Definition

Lymphoma that originates in the stomach itself. [from HPO]

Conditions with this feature

Mucosa-associated lymphoma
MedGen UID:
66942
•Concept ID:
C0242647
•
Neoplastic Process
MALT (mucosa-associated lymphoid tissue) lymphoma is a rare form of malignant non-Hodgkin lymphoma (see this term) that affects B cells and grows at the expense of lymphoid tissue associated with mucous membranes, but also occurs, more rarely, in lymph nodes.
See: Condition Record
Mucosa-associated lymphoma

Professional guidelines

PubMed

MALT lymphoma: epidemiology, clinical diagnosis and treatment.
Violeta Filip P, Cuciureanu D, Sorina Diaconu L, Maria Vladareanu A, Silvia Pop C
J Med Life 2018 Jul-Sep;11(3):187-193. doi: 10.25122/jml-2018-0035. PMID: 30364585Free PMC Article
Multimodality Treatment of Gastric Lymphoma.
Ikoma N, Badgwell BD, Mansfield PF
Surg Clin North Am 2017 Apr;97(2):405-420. Epub 2017 Feb 14 doi: 10.1016/j.suc.2016.11.012. PMID: 28325194
Diagnosis, treatment decisions, and follow up in primary gastric lymphoma.
Boot H, de Jong D
Gut 2002 Nov;51(5):621-2. doi: 10.1136/gut.51.5.621. PMID: 12377794Free PMC Article

Recent clinical studies

Etiology

Post-transplant Lymphoproliferative Disorder.
Chowdhary GS, Jhala M
J Assoc Physicians India 2017 Dec;65(12):102-103. PMID: 29327533
Primary Gastric Hodgkin's Lymphoma: An Extremely Rare Entity and A Diagnostic Challenge.
Sethi S, Higgins JP, Arber DA, Visser B, Banerjee S
Dig Dis Sci 2015 Oct;60(10):2923-6. Epub 2015 Mar 12 doi: 10.1007/s10620-015-3616-x. PMID: 25761826
De-escalating therapy in gastric aggressive lymphoma.
Cuccurullo R, Govi S, Ferreri AJ
World J Gastroenterol 2014 Jul 21;20(27):8993-7. doi: 10.3748/wjg.v20.i27.8993. PMID: 25083073Free PMC Article
Gastric marginal zone lymphoma of MALT type: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Zucca E, Copie-Bergman C, Ricardi U, Thieblemont C, Raderer M, Ladetto M; ESMO Guidelines Working Group
Ann Oncol 2013 Oct;24 Suppl 6:vi144-8. doi: 10.1093/annonc/mdt343. PMID: 24078657
Helicobacter pylori: epidemiology and routes of transmission.
Brown LM
Epidemiol Rev 2000;22(2):283-97. doi: 10.1093/oxfordjournals.epirev.a018040. PMID: 11218379

Diagnosis

Gastric MALT lymphoma and Helicobacter pylori.
Salar A
Med Clin (Barc) 2019 Jan 18;152(2):65-71. Epub 2018 Nov 10 doi: 10.1016/j.medcli.2018.09.006. PMID: 30424932
MALT lymphoma: epidemiology, clinical diagnosis and treatment.
Violeta Filip P, Cuciureanu D, Sorina Diaconu L, Maria Vladareanu A, Silvia Pop C
J Med Life 2018 Jul-Sep;11(3):187-193. doi: 10.25122/jml-2018-0035. PMID: 30364585Free PMC Article
Gastric marginal zone lymphoma of MALT type: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Zucca E, Copie-Bergman C, Ricardi U, Thieblemont C, Raderer M, Ladetto M; ESMO Guidelines Working Group
Ann Oncol 2013 Oct;24 Suppl 6:vi144-8. doi: 10.1093/annonc/mdt343. PMID: 24078657
Helicobacter pylori.
Parsonnet J
Infect Dis Clin North Am 1998 Mar;12(1):185-97. doi: 10.1016/s0891-5520(05)70417-7. PMID: 9494838
Helicobacter pylori.
Dunn BE, Cohen H, Blaser MJ
Clin Microbiol Rev 1997 Oct;10(4):720-41. doi: 10.1128/CMR.10.4.720. PMID: 9336670Free PMC Article

Therapy

Post-transplant Lymphoproliferative Disorder.
Chowdhary GS, Jhala M
J Assoc Physicians India 2017 Dec;65(12):102-103. PMID: 29327533
De-escalating therapy in gastric aggressive lymphoma.
Cuccurullo R, Govi S, Ferreri AJ
World J Gastroenterol 2014 Jul 21;20(27):8993-7. doi: 10.3748/wjg.v20.i27.8993. PMID: 25083073Free PMC Article
Gastric marginal zone lymphoma of MALT type: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Zucca E, Copie-Bergman C, Ricardi U, Thieblemont C, Raderer M, Ladetto M; ESMO Guidelines Working Group
Ann Oncol 2013 Oct;24 Suppl 6:vi144-8. doi: 10.1093/annonc/mdt343. PMID: 24078657
Helicobacter pylori.
Parsonnet J
Infect Dis Clin North Am 1998 Mar;12(1):185-97. doi: 10.1016/s0891-5520(05)70417-7. PMID: 9494838
Helicobacter pylori.
Dunn BE, Cohen H, Blaser MJ
Clin Microbiol Rev 1997 Oct;10(4):720-41. doi: 10.1128/CMR.10.4.720. PMID: 9336670Free PMC Article

Prognosis

MALT lymphoma: epidemiology, clinical diagnosis and treatment.
Violeta Filip P, Cuciureanu D, Sorina Diaconu L, Maria Vladareanu A, Silvia Pop C
J Med Life 2018 Jul-Sep;11(3):187-193. doi: 10.25122/jml-2018-0035. PMID: 30364585Free PMC Article
De-escalating therapy in gastric aggressive lymphoma.
Cuccurullo R, Govi S, Ferreri AJ
World J Gastroenterol 2014 Jul 21;20(27):8993-7. doi: 10.3748/wjg.v20.i27.8993. PMID: 25083073Free PMC Article
Gastric marginal zone lymphoma of MALT type: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Zucca E, Copie-Bergman C, Ricardi U, Thieblemont C, Raderer M, Ladetto M; ESMO Guidelines Working Group
Ann Oncol 2013 Oct;24 Suppl 6:vi144-8. doi: 10.1093/annonc/mdt343. PMID: 24078657
Synchronous and metachronous occurrence of gastric adenocarcinoma and gastric lymphoma: A review of the literature.
Hamaloglu E, Topaloglu S, Ozdemir A, Ozenc A
World J Gastroenterol 2006 Jun 14;12(22):3564-74. doi: 10.3748/wjg.v12.i22.3564. PMID: 16773713Free PMC Article
Update on gastric lymphoma.
Thomas CR Jr
J Natl Med Assoc 1991 Aug;83(8):713-8. PMID: 1956083Free PMC Article

Clinical prediction guides

Primary Canalicular MALT Lymphoma Masquerading as Chronic Canaliculitis.
Reding M, Nolan R, Mudie LI, Shetlar DJ, Yen MT
Ophthalmic Plast Reconstr Surg 2024 Mar-Apr 01;40(2):e51-e52. Epub 2023 Dec 19 doi: 10.1097/IOP.0000000000002568. PMID: 38133611
Gastric CD56-negative Extranodal Natural Killer/T-cell Lymphoma: A Case Report.
Chung J, Jee SR, Choi E, Yu SJ, Yoon JS, Lee HS, Lee SH, Park SJ, Park HY
Korean J Gastroenterol 2022 Oct 25;80(4):190-194. doi: 10.4166/kjg.2022.076. PMID: 36281552
Gastric MALT lymphoma and Helicobacter pylori.
Salar A
Med Clin (Barc) 2019 Jan 18;152(2):65-71. Epub 2018 Nov 10 doi: 10.1016/j.medcli.2018.09.006. PMID: 30424932
PET/Computed Tomography and Precision Medicine: Gastric Cancer.
Marcus C, Subramaniam RM
PET Clin 2017 Oct;12(4):437-447. Epub 2017 Jul 15 doi: 10.1016/j.cpet.2017.05.004. PMID: 28867114
MALT Lymphomas.
Cavalli F, Isaacson PG, Gascoyne RD, Zucca E
Hematology Am Soc Hematol Educ Program 2001:241-58. doi: 10.1182/asheducation-2001.1.241. PMID: 11722987

Recent systematic reviews

Radiotherapy in the management of rare gastrointestinal cancers: A systematic review.
Bellefkih FZ, Benchakroun N, Lalya I, Amaoui B, El Kacemi H, Acharki A, El Hfid M, El Mazghi A, Chekrine T, Bouchbika Z, Jouhadi H, Sahraoui S, Tawfiq N, Michalet M
Cancer Radiother 2023 Sep;27(6-7):622-637. Epub 2023 Jul 25 doi: 10.1016/j.canrad.2023.06.010. PMID: 37500390
Efficacy of Helicobater pylori eradication in patients with diffuse large B-cell lymphoma of the stomach: A systematic review.
De Francesco V, Manta R, Marmo R, Marmo C, Rago A, Antonelli G, Hassan C, Zullo A
Eur J Haematol 2022 Dec;109(6):643-647. Epub 2022 Oct 5 doi: 10.1111/ejh.13871. PMID: 36175387
A systematic review of primary gastric diffuse large B-cell lymphoma: Clinical diagnosis, staging, treatment and prognostic factors.
Bai Z, Zhou Y
Leuk Res 2021 Dec;111:106716. Epub 2021 Oct 1 doi: 10.1016/j.leukres.2021.106716. PMID: 34627052
Primary low-grade and high-grade gastric MALT-lymphoma presentation.
Zullo A, Hassan C, Andriani A, Cristofari F, Cardinale V, Spinelli GP, Tomao S, Morini S
J Clin Gastroenterol 2010 May-Jun;44(5):340-4. doi: 10.1097/MCG.0b013e3181b4b1ab. PMID: 19745757
Effects of Helicobacter pylori eradication on early stage gastric mucosa-associated lymphoid tissue lymphoma.
Zullo A, Hassan C, Cristofari F, Andriani A, De Francesco V, Ierardi E, Tomao S, Stolte M, Morini S, Vaira D
Clin Gastroenterol Hepatol 2010 Feb;8(2):105-10. Epub 2009 Jul 22 doi: 10.1016/j.cgh.2009.07.017. PMID: 19631287

Supplemental Content

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