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Bladder Sphincter Dysfunction

MedGen UID:
882943
•Concept ID:
C4055377
•
Disease or Syndrome

Definition

Non-coordinated, reflexive contraction of the bladder and sphincter relaxation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBladder Sphincter Dysfunction

Professional guidelines

PubMed

Treatment outcomes according to neuropathic bladder sphincter dysfunction type after treatment of oxybutynin chloride in children with myelodysplasia.
Baek M, Kang JY, Jeong J, Kim DK, Kim KM
Int Urol Nephrol 2013 Jun;45(3):703-9. Epub 2013 Mar 31 doi: 10.1007/s11255-013-0423-1. PMID: 23543139
The neurogenic bladder: medical treatment.
Verpoorten C, Buyse GM
Pediatr Nephrol 2008 May;23(5):717-25. Epub 2007 Dec 19 doi: 10.1007/s00467-007-0691-z. PMID: 18095004Free PMC Article
The role of pelvic-floor therapy in the treatment of lower urinary tract dysfunctions in children.
De Paepe H, Renson C, Hoebeke P, Raes A, Van Laecke E, Vande Walle J
Scand J Urol Nephrol 2002;36(4):260-7. doi: 10.1080/003655902320248218. PMID: 12201917

Recent clinical studies

Etiology

Renal preservation in children with neurogenic bladder-sphincter dysfunction followed in a national program.
Wide P, Glad Mattsson G, Mattsson S
J Pediatr Urol 2012 Apr;8(2):187-93. Epub 2011 Mar 15 doi: 10.1016/j.jpurol.2011.02.003. PMID: 21411372
The neurogenic bladder: medical treatment.
Verpoorten C, Buyse GM
Pediatr Nephrol 2008 May;23(5):717-25. Epub 2007 Dec 19 doi: 10.1007/s00467-007-0691-z. PMID: 18095004Free PMC Article
Colpo-wrap: a new continence procedure.
Boemers TM, Schimke CM
BJU Int 2005 May;95(7):1063-4. doi: 10.1111/j.1464-410X.2005.05467.x. PMID: 15839933
The role of pelvic-floor therapy in the treatment of lower urinary tract dysfunctions in children.
De Paepe H, Renson C, Hoebeke P, Raes A, Van Laecke E, Vande Walle J
Scand J Urol Nephrol 2002;36(4):260-7. doi: 10.1080/003655902320248218. PMID: 12201917
Bladder-sphincter dysfunction in myelomeningocele.
van Gool JD, Dik P, de Jong TP
Eur J Pediatr 2001 Jul;160(7):414-20. doi: 10.1007/s004310100741. PMID: 11475578

Diagnosis

Renal preservation in children with neurogenic bladder-sphincter dysfunction followed in a national program.
Wide P, Glad Mattsson G, Mattsson S
J Pediatr Urol 2012 Apr;8(2):187-93. Epub 2011 Mar 15 doi: 10.1016/j.jpurol.2011.02.003. PMID: 21411372
The role of pelvic-floor therapy in the treatment of lower urinary tract dysfunctions in children.
De Paepe H, Renson C, Hoebeke P, Raes A, Van Laecke E, Vande Walle J
Scand J Urol Nephrol 2002;36(4):260-7. doi: 10.1080/003655902320248218. PMID: 12201917
Bladder-sphincter dysfunction in myelomeningocele.
van Gool JD, Dik P, de Jong TP
Eur J Pediatr 2001 Jul;160(7):414-20. doi: 10.1007/s004310100741. PMID: 11475578
Assessment of lower urinary tract dysfunction in children with non-neuropathic bladder sphincter dysfunction.
Hoebeke P, Vande Walle J, Everaert K, Van Laecke E, Van Gool JD
Eur Urol 1999 Jan;35(1):57-69. doi: 10.1159/000019820. PMID: 9933796
Bladder-sphincter dysfunction in childhood.
Koff SA
Urology 1982 May;19(5):457-61. doi: 10.1016/0090-4295(82)90598-2. PMID: 7080315

Therapy

Long-term outcome of intravesical oxybutynin in children with detrusor-sphincter dyssynergia: with special reference to age-dependent parameters.
Humblet M, Verpoorten C, Christiaens MH, Hirche H, Jansen K, Buyse G, van Gool JD
Neurourol Urodyn 2015 Apr;34(4):336-42. Epub 2014 Jan 16 doi: 10.1002/nau.22560. PMID: 24436114
Treatment outcomes according to neuropathic bladder sphincter dysfunction type after treatment of oxybutynin chloride in children with myelodysplasia.
Baek M, Kang JY, Jeong J, Kim DK, Kim KM
Int Urol Nephrol 2013 Jun;45(3):703-9. Epub 2013 Mar 31 doi: 10.1007/s11255-013-0423-1. PMID: 23543139
The AdVance male sling as a minimally invasive treatment for intrinsic sphincter deficiency in patients with neurogenic bladder sphincter dysfunction: a pilot study.
Groen LA, Spinoit AF, Hoebeke P, Van Laecke E, De Troyer B, Everaert K
Neurourol Urodyn 2012 Nov;31(8):1284-7. Epub 2012 Jul 27 doi: 10.1002/nau.21256. PMID: 22847896
Behavior profiles in children with functional urinary incontinence before and after incontinence treatment.
Bael A, Winkler P, Lax H, Hirche H, Gäbel E, Vijverberg M, van Zon R, Van Hoecke E, van Gool JD
Pediatrics 2008 May;121(5):e1196-200. doi: 10.1542/peds.2007-1652. PMID: 18450862
The neurogenic bladder: medical treatment.
Verpoorten C, Buyse GM
Pediatr Nephrol 2008 May;23(5):717-25. Epub 2007 Dec 19 doi: 10.1007/s00467-007-0691-z. PMID: 18095004Free PMC Article

Prognosis

Treatment outcomes according to neuropathic bladder sphincter dysfunction type after treatment of oxybutynin chloride in children with myelodysplasia.
Baek M, Kang JY, Jeong J, Kim DK, Kim KM
Int Urol Nephrol 2013 Jun;45(3):703-9. Epub 2013 Mar 31 doi: 10.1007/s11255-013-0423-1. PMID: 23543139
Renal preservation in children with neurogenic bladder-sphincter dysfunction followed in a national program.
Wide P, Glad Mattsson G, Mattsson S
J Pediatr Urol 2012 Apr;8(2):187-93. Epub 2011 Mar 15 doi: 10.1016/j.jpurol.2011.02.003. PMID: 21411372
The role of pelvic-floor therapy in the treatment of lower urinary tract dysfunctions in children.
De Paepe H, Renson C, Hoebeke P, Raes A, Van Laecke E, Vande Walle J
Scand J Urol Nephrol 2002;36(4):260-7. doi: 10.1080/003655902320248218. PMID: 12201917
Bladder-sphincter dysfunction in myelomeningocele.
van Gool JD, Dik P, de Jong TP
Eur J Pediatr 2001 Jul;160(7):414-20. doi: 10.1007/s004310100741. PMID: 11475578
Assessment of lower urinary tract dysfunction in children with non-neuropathic bladder sphincter dysfunction.
Hoebeke P, Vande Walle J, Everaert K, Van Laecke E, Van Gool JD
Eur Urol 1999 Jan;35(1):57-69. doi: 10.1159/000019820. PMID: 9933796

Clinical prediction guides

Four-hour voiding observation with provocation test reveals significant abnormalities of bladder function in newborns with spinal dysraphism.
Wide P, Duchén K, Mattsson S, Glad Mattsson G
J Pediatr Urol 2020 Aug;16(4):491.e1-491.e7. Epub 2020 Jun 20 doi: 10.1016/j.jpurol.2020.06.022. PMID: 32782223
The AdVance male sling as a minimally invasive treatment for intrinsic sphincter deficiency in patients with neurogenic bladder sphincter dysfunction: a pilot study.
Groen LA, Spinoit AF, Hoebeke P, Van Laecke E, De Troyer B, Everaert K
Neurourol Urodyn 2012 Nov;31(8):1284-7. Epub 2012 Jul 27 doi: 10.1002/nau.21256. PMID: 22847896
Percutaneous electrical nerve stimulation in children with therapy resistant nonneuropathic bladder sphincter dysfunction: a pilot study.
Hoebeke P, Renson C, Petillon L, Vande Walle J, De Paepe H
J Urol 2002 Dec;168(6):2605-7; discussion 2607-8. doi: 10.1016/S0022-5347(05)64227-9. PMID: 12441995
The role of pelvic-floor therapy in the treatment of lower urinary tract dysfunctions in children.
De Paepe H, Renson C, Hoebeke P, Raes A, Van Laecke E, Vande Walle J
Scand J Urol Nephrol 2002;36(4):260-7. doi: 10.1080/003655902320248218. PMID: 12201917
Lower urinary tract dysfunction in children with benign sacrococcygeal teratoma.
Boemers TM, van Gool JD, de Jong TP, Bax KM
J Urol 1994 Jan;151(1):174-6. doi: 10.1016/s0022-5347(17)34909-1. PMID: 8254808

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