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Trigeminal nerve palsy

MedGen UID:
884229
•Concept ID:
C4075565
•
Disease or Syndrome
Synonyms: Cranial nerve 5 palsy; Cranial Nerve V Palsy; Fifth Cranial Nerve Palsy; Fifth nerve palsy; Trigeminal Nerve Palsy
SNOMED CT: Trigeminal nerve palsy (714027006); Cranial nerve 5 palsy (714027006); Fifth nerve palsy (714027006)

Definition

Partial or complete paralysis of the trigeminal nerve. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTrigeminal nerve palsy

Professional guidelines

PubMed

Neurofibromatosis Type II and Facial Paralysis: Clinical Evaluation and Management.
Mohanty AJ, DeVahl J, Kutz WJ, Rozen SM
Plast Reconstr Surg 2024 Feb 1;153(2):415e-423e. Epub 2023 Apr 20 doi: 10.1097/PRS.0000000000010561. PMID: 37075282
Evaluation and management of herpes zoster ophthalmicus.
Shaikh S, Ta CN
Am Fam Physician 2002 Nov 1;66(9):1723-30. PMID: 12449270
Cranial nerve, brainstem and cerebellar syndromes in the differential diagnosis of multiple sclerosis.
Zaffaroni M, Baldini SM, Ghezzi A
Neurol Sci 2001 Nov;22 Suppl 2:S74-8. doi: 10.1007/s100720100039. PMID: 11794483

Recent clinical studies

Etiology

Embolization of Cavernous Sinus Dural Arteriovenous Fistula with Liquid Materials Under Transarterial Balloon Protection.
Li JN, Shang CH, Xu Y, Liu JM, Li Q
Turk Neurosurg 2023;33(6):967-975. doi: 10.5137/1019-5149.JTN.40189-22.2. PMID: 37885308
Outcomes of corneal neurotisation using processed nerve allografts: a multicentre case series.
Sweeney AR, Wang M, Weller CL, Burkat C, Kossler AL, Lee BW, Yen MT
Br J Ophthalmol 2022 Mar;106(3):326-330. Epub 2020 Nov 16 doi: 10.1136/bjophthalmol-2020-317361. PMID: 33199302
The surgical management of extra-cranial trigeminal nerve palsies: A retrospective case series.
Dr T, E P, J D, S H, R M, I K, C N, Ry K
J Plast Reconstr Aesthet Surg 2021 Sep;74(9):2258-2264. Epub 2020 Dec 26 doi: 10.1016/j.bjps.2020.12.055. PMID: 33422495
Trigeminal nerve palsy in nasopharyngeal carcinoma: correlation between clinical findings and magnetic resonance imaging.
Cui C, Liu L, Ma J, Liang S, Tian L, Tang L, Li L
Head Neck 2009 Jun;31(6):822-8. doi: 10.1002/hed.21101. PMID: 19373779
Horner's syndrome and trigeminal nerve palsy following epidural analgesia for labor.
Lynch JH, Keneally RJ, Hustead TR
J Am Board Fam Med 2006 Sep-Oct;19(5):521-3. doi: 10.3122/jabfm.19.5.521. PMID: 16951303

Diagnosis

Heerfordt's Syndrome Associated with Trigeminal Nerve Palsy and Reversed Halo Sign.
Makimoto G, Kawakado K, Nakanishi M, Tamura T, Noda M, Makimoto S, Sato Y, Kuyama S
Intern Med 2021 Jun 1;60(11):1747-1752. Epub 2020 Dec 29 doi: 10.2169/internalmedicine.6176-20. PMID: 33390492Free PMC Article
Horner's syndrome following obstetric neuraxial blockade - a systematic review of the literature.
Chambers DJ, Bhatia K
Int J Obstet Anesth 2018 Aug;35:75-87. Epub 2018 Mar 17 doi: 10.1016/j.ijoa.2018.03.005. PMID: 29657082
Thirteen-And-A-Half Syndrome.
Allbon DS, La Hood B
J Neuroophthalmol 2016 Jun;36(2):191-2. doi: 10.1097/WNO.0000000000000341. PMID: 26928599
Case of Sjögren's syndrome presenting as trigeminal nerve palsy.
Horai Y, Nishino A, Nakashima Y, Suzuki T, Okada A, Kawashiri SY, Tamai M, Yamasaki S, Nakamura H, Origuchi T, Kawakami A
Nihon Rinsho Meneki Gakkai Kaishi 2012;35(3):199-202. doi: 10.2177/jsci.35.199. PMID: 22790581
Trigeminal nerve palsy in nasopharyngeal carcinoma: correlation between clinical findings and magnetic resonance imaging.
Cui C, Liu L, Ma J, Liang S, Tian L, Tang L, Li L
Head Neck 2009 Jun;31(6):822-8. doi: 10.1002/hed.21101. PMID: 19373779

Therapy

Horner's syndrome following obstetric neuraxial blockade - a systematic review of the literature.
Chambers DJ, Bhatia K
Int J Obstet Anesth 2018 Aug;35:75-87. Epub 2018 Mar 17 doi: 10.1016/j.ijoa.2018.03.005. PMID: 29657082
Laser in situ keratomileusis flap necrosis after trigeminal nerve palsy.
Rocha GA, Acera A, Durán JA
Arch Ophthalmol 2007 Oct;125(10):1423-5. doi: 10.1001/archopht.125.10.1423. PMID: 17923556
Trigeminal nerve palsy and Horner's syndrome following epidural analgesia for labor: a subdural block?
De la Gala F, Reyes A, Avellanal M, Baticón P, González-Zarco LM
Int J Obstet Anesth 2007 Apr;16(2):180-2. Epub 2007 Jan 30 doi: 10.1016/j.ijoa.2006.07.007. PMID: 17270429
Horner's syndrome and trigeminal nerve palsy following epidural analgesia for labor.
Lynch JH, Keneally RJ, Hustead TR
J Am Board Fam Med 2006 Sep-Oct;19(5):521-3. doi: 10.3122/jabfm.19.5.521. PMID: 16951303
Vesicular eruption in a child with trigeminal nerve palsy during topical therapy with substance p and insulinlike growth factor I for neurotrophic keratitis.
Brown SM, Khanani AM, Stetson CL, Reid TW
Arch Ophthalmol 2004 Nov;122(11):1722-3. doi: 10.1001/archopht.122.11.1722. PMID: 15534142

Prognosis

Case Report: Isolated facial and trigeminal nerve palsy without ataxia in anti-GQ1b antibody syndrome secondary to Mycoplasma pneumonia.
Deng S, Yin L, Lu W, Ouyang S, Yin W
Front Immunol 2022;13:1062567. Epub 2022 Dec 14 doi: 10.3389/fimmu.2022.1062567. PMID: 36591271Free PMC Article
A fatal case of Gradenigo's syndrome in Zimbabwe and the Danish-Zimbabwean ENT collaboration.
Jensen PVF, Avnstorp MB, Dzongodza T, Chidziva C, von Buchwald C
Int J Pediatr Otorhinolaryngol 2017 Jun;97:181-184. Epub 2017 Apr 11 doi: 10.1016/j.ijporl.2017.04.014. PMID: 28483232
Trigeminal nerve palsy in nasopharyngeal carcinoma: correlation between clinical findings and magnetic resonance imaging.
Cui C, Liu L, Ma J, Liang S, Tian L, Tang L, Li L
Head Neck 2009 Jun;31(6):822-8. doi: 10.1002/hed.21101. PMID: 19373779
Treatment of cranial base meningiomas with linear accelerator radiosurgery.
Chang SD, Adler JR Jr
Neurosurgery 1997 Nov;41(5):1019-25; discussion 1025-7. doi: 10.1097/00006123-199711000-00003. PMID: 9361055
The early effects of gamma knife on 40 cases of acoustic neurinoma.
Kobayashi T, Tanaka T, Kida Y
Acta Neurochir Suppl 1994;62:93-7. doi: 10.1007/978-3-7091-9371-6_19. PMID: 7717145

Clinical prediction guides

Case Report: Isolated facial and trigeminal nerve palsy without ataxia in anti-GQ1b antibody syndrome secondary to Mycoplasma pneumonia.
Deng S, Yin L, Lu W, Ouyang S, Yin W
Front Immunol 2022;13:1062567. Epub 2022 Dec 14 doi: 10.3389/fimmu.2022.1062567. PMID: 36591271Free PMC Article
Giant cell arteritis: clinical features of patients visiting a headache clinic in Japan.
Imai N, Kuroda R, Konishi T, Serizawa M, Kobari M
Intern Med 2011;50(16):1679-82. Epub 2011 Aug 15 doi: 10.2169/internalmedicine.50.5205. PMID: 21841325
Surgery of cerebellopontine angle epidermoid cysts: role of the widened retrolabyrinthine approach combined with endoscopy.
Darrouzet V, Franco-Vidal V, Hilton M, Nguyen DQ, Lacher-Fougere S, Guerin J, Bebear JP
Otolaryngol Head Neck Surg 2004 Jul;131(1):120-5. doi: 10.1016/j.otohns.2004.02.023. PMID: 15243568
The early effects of gamma knife on 40 cases of acoustic neurinoma.
Kobayashi T, Tanaka T, Kida Y
Acta Neurochir Suppl 1994;62:93-7. doi: 10.1007/978-3-7091-9371-6_19. PMID: 7717145

Recent systematic reviews

Horner's syndrome following obstetric neuraxial blockade - a systematic review of the literature.
Chambers DJ, Bhatia K
Int J Obstet Anesth 2018 Aug;35:75-87. Epub 2018 Mar 17 doi: 10.1016/j.ijoa.2018.03.005. PMID: 29657082

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