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Meningioangiomatosis

MedGen UID:: 890255
•Concept ID:: C4054534
•: Disease or Syndrome

Definition

A rare vascular malformation in the cerebral cortex and overlying leptomeninges. It can occur sporadically or in association with neurofibromatosis type 2. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMeningioangiomatosis

Phenotypic abnormality
- Abnormality of prenatal development or birth
  - Fetal anomaly
    - Congenital Systemic Disorder
      - Abnormality of the nervous system
        Vascular malformation of the nervous system
        Meningioangiomatosis

Professional guidelines

PubMed

Diagnosis and surgical treatment of sporadic meningioangiomatosis.

Feng R, Hu J, Che X, Pan L, Wang Z, Zhang M, Huang F, Xu B, Mao R, Sun A, Bao W, Zhong P, Wang Y
Clin Neurol Neurosurg 2013 Aug;115(8):1407-14. Epub 2013 Feb 26 doi: 10.1016/j.clineuro.2013.01.021. PMID: 23485253

See all (1)

Recent clinical studies

Etiology

Pure and non-pure meningioangiomatosis of 36 Chinese patients: an analysis of clinical presentation, diagnosis, histopathology and prognosis.

Zhang GB, Ying YZ, Huang HW, Yu WJ, Li HY, Zhang XK, Wang YG, Cui Y, Chen Y, Jiang ZL, Lin S
Neurosurg Rev 2022 Oct;45(5):3405-3415. Epub 2022 Sep 5 doi: 10.1007/s10143-022-01855-8. PMID: 36063221

Focal cortical dysplasia in meningioangiomatosis.

Grabowski MM, Prayson RA
Clin Neuropathol 2015 Mar-Apr;34(2):76-82. doi: 10.5414/NP300820. PMID: 25601060

ILAE focal cortical dysplasia type IIIc in the ictal onset zone in epileptic patients with solitary meningioangiomatosis.

Mukae N, Suzuki SO, Morioka T, Murakami N, Hashiguchi K, Shigeto H, Sakata A, Iihara K
Epileptic Disord 2014 Dec;16(4):533-9. doi: 10.1684/epd.2014.0695. PMID: 25366924

Intraparenchymal meningioma originating from underlying meningioangiomatosis. Case report and review of the literature.

Mut M, Söylemezoğlu F, Firat MM, Palaoğlu S
J Neurosurg 2000 Apr;92(4):706-10. doi: 10.3171/jns.2000.92.4.0706. PMID: 10761664

Meningioangiomatosis. A clinicopathologic study including MIB1 immunoreactivity.

Prayson RA
Arch Pathol Lab Med 1995 Nov;119(11):1061-4. PMID: 7487408

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Diagnosis

Meningioangiomatosis: Multimodal Analysis and Insights From a Systematic Review.

Roux A, Zanello M, Mancusi RL, Still MEH, Nascimento FA, Tauziede-Espariat A, Huberfeld G, Zah-Bi G, Dezamis E, Meder JF, Bourgeois M, Parraga E, Chretien F, Varlet P, Oppenheim C, Lechapt-Zalcman E, Pallud J
Neurology 2021 Feb 9;96(6):274-286. Epub 2020 Dec 22 doi: 10.1212/WNL.0000000000011372. PMID: 33361266

An update on the CNS manifestations of neurofibromatosis type 2.

Coy S, Rashid R, Stemmer-Rachamimov A, Santagata S
Acta Neuropathol 2020 Apr;139(4):643-665. Epub 2019 Jun 4 doi: 10.1007/s00401-019-02029-5. PMID: 31161239 Free PMC Article

Meningioangiomatosis: A review of the variable manifestations and complex pathophysiology.

Tomkinson C, Lu JQ
J Neurol Sci 2018 Sep 15;392:130-136. Epub 2018 Jul 24 doi: 10.1016/j.jns.2018.07.018. PMID: 30056201

Multicystic meningioangiomatosis.

Li P, Cui G, Wang Y, Geng M, Wang Z
BMC Neurol 2014 Feb 20;14:32. doi: 10.1186/1471-2377-14-32. PMID: 24555776 Free PMC Article

Meningioangiomatosis is associated with neurofibromatosis 2 but not with somatic alterations of the NF2 gene.

Stemmer-Rachamimov AO, Horgan MA, Taratuto AL, Munoz DG, Smith TW, Frosch MP, Louis DN
J Neuropathol Exp Neurol 1997 May;56(5):485-9. doi: 10.1097/00005072-199705000-00004. PMID: 9143261

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Therapy

Progressive diffuse meningioangiomatosis: Response to bevacizumab treatment.

Yust-Katz S, Fuller G, Fichman-Horn S, Michaeli N, Inbar E, Lukman J, Limon D, Steiner I, Siegal T
Neurology 2016 Apr 26;86(17):1643-4. Epub 2016 Mar 30 doi: 10.1212/WNL.0000000000002610. PMID: 27029633 Free PMC Article

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Prognosis

Pure and non-pure meningioangiomatosis of 36 Chinese patients: an analysis of clinical presentation, diagnosis, histopathology and prognosis.

Zhang GB, Ying YZ, Huang HW, Yu WJ, Li HY, Zhang XK, Wang YG, Cui Y, Chen Y, Jiang ZL, Lin S
Neurosurg Rev 2022 Oct;45(5):3405-3415. Epub 2022 Sep 5 doi: 10.1007/s10143-022-01855-8. PMID: 36063221

Meningioangiomatosis: Multimodal Analysis and Insights From a Systematic Review.

An update on the CNS manifestations of neurofibromatosis type 2.

Coy S, Rashid R, Stemmer-Rachamimov A, Santagata S
Acta Neuropathol 2020 Apr;139(4):643-665. Epub 2019 Jun 4 doi: 10.1007/s00401-019-02029-5. PMID: 31161239 Free PMC Article

Childhood meningiomas associated with meningioangiomatosis: report of five cases and literature review.

Kim NR, Choe G, Shin SH, Wang KC, Cho BK, Choi KS, Chi JG
Neuropathol Appl Neurobiol 2002 Feb;28(1):48-56. doi: 10.1046/j.1365-2990.2002.00365.x. PMID: 11849563

A case of meningioangiomatosis without von Recklinghausen's disease. Report of a case and review of 13 cases.

Harada K, Inagawa T, Nagasako R
Childs Nerv Syst 1994 Mar;10(2):126-30. doi: 10.1007/BF00302777. PMID: 8033161

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Clinical prediction guides

Meningioangiomatosis: Multimodal Analysis and Insights From a Systematic Review.

Left Frontal Meningioangiomatosis Associated with Type IIIc Focal Cortical Dysplasia Causing Refractory Epilepsy and Literature Review.

Roux A, Mellerio C, Lechapt-Zalcman E, Still M, Zerah M, Bourgeois M, Pallud J
World Neurosurg 2018 Jun;114:281-288. Epub 2018 Mar 30 doi: 10.1016/j.wneu.2018.03.145. PMID: 29605698

Intraparenchymal meningioma originating from underlying meningioangiomatosis. Case report and review of the literature.

Mut M, Söylemezoğlu F, Firat MM, Palaoğlu S
J Neurosurg 2000 Apr;92(4):706-10. doi: 10.3171/jns.2000.92.4.0706. PMID: 10761664

Meningioma with meningioangiomatosis: a condition mimicking invasive meningiomas in children and young adults: report of two cases and review of the literature.

Giangaspero F, Guiducci A, Lenz FA, Mastronardi L, Burger PC
Am J Surg Pathol 1999 Aug;23(8):872-5. doi: 10.1097/00000478-199908000-00002. PMID: 10435554

A case of meningioangiomatosis without von Recklinghausen's disease. Report of a case and review of 13 cases.

Harada K, Inagawa T, Nagasako R
Childs Nerv Syst 1994 Mar;10(2):126-30. doi: 10.1007/BF00302777. PMID: 8033161

See all (10)