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Abnormal adiponectin level

MedGen UID:
892755
Concept ID:
C4073126
Finding
HPO: HP:0030684

Definition

A deviation from the normal circulating concentration of adiponectin, a 30-kDa complement C1-related protein that is the most abundant secreted protein expressed in adipose tissue, and that plays a crucial role in the regulation of insulin sensitivity and glucose metabolism. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal adiponectin level

Professional guidelines

PubMed

Coutinho CAAC, Marson FAL, Ribeiro JD, Bertuzzo CS
Pulmonology 2020 May-Jun;26(3):138-144. Epub 2019 Oct 9 doi: 10.1016/j.pulmoe.2019.09.003. PMID: 31606405
Ibáñez L, Oberfield SE, Witchel S, Auchus RJ, Chang RJ, Codner E, Dabadghao P, Darendeliler F, Elbarbary NS, Gambineri A, Garcia Rudaz C, Hoeger KM, López-Bermejo A, Ong K, Peña AS, Reinehr T, Santoro N, Tena-Sempere M, Tao R, Yildiz BO, Alkhayyat H, Deeb A, Joel D, Horikawa R, de Zegher F, Lee PA
Horm Res Paediatr 2017;88(6):371-395. Epub 2017 Nov 13 doi: 10.1159/000479371. PMID: 29156452
van de Woestijne AP, Monajemi H, Kalkhoven E, Visseren FL
Obes Rev 2011 Oct;12(10):829-40. Epub 2011 Jul 12 doi: 10.1111/j.1467-789X.2011.00900.x. PMID: 21749607

Recent clinical studies

Etiology

Tural U, Iosifescu DV
Int J Eat Disord 2022 Oct;55(10):1279-1290. Epub 2022 Jun 11 doi: 10.1002/eat.23753. PMID: 35689560
Borshuliak AV, Andriiets OA, Bakun OV, Andriiets AV, Andriiets VV, Sheremet MI, Varlas VN
J Med Life 2021 Nov-Dec;14(6):834-840. doi: 10.25122/jml-2021-0312. PMID: 35126755Free PMC Article
Er LK, Wu S, Chou HH, Hsu LA, Teng MS, Sun YC, Ko YL
PLoS One 2016;11(3):e0149731. Epub 2016 Mar 1 doi: 10.1371/journal.pone.0149731. PMID: 26930652Free PMC Article
Li Q, Zhang J, Zhou Y, Qiao L
Front Biosci (Landmark Ed) 2012 Jun 1;17(7):2383-90. doi: 10.2741/4059. PMID: 22652786
Ioannidis I
Angiology 2008 Apr-May;59(2 Suppl):39S-43S. Epub 2008 May 27 doi: 10.1177/0003319708318583. PMID: 18505743

Diagnosis

Qian Y, Xia F, Zuo Y, Zhong M, Yang L, Jiang Y, Zou C
Orphanet J Rare Dis 2022 May 7;17(1):187. doi: 10.1186/s13023-022-02344-3. PMID: 35525976Free PMC Article
Gutaj P, Sibiak R, Jankowski M, Awdi K, Bryl R, Mozdziak P, Kempisty B, Wender-Ozegowska E
Int J Mol Sci 2020 Dec 10;21(24) doi: 10.3390/ijms21249408. PMID: 33321877Free PMC Article
Ibáñez L, Oberfield SE, Witchel S, Auchus RJ, Chang RJ, Codner E, Dabadghao P, Darendeliler F, Elbarbary NS, Gambineri A, Garcia Rudaz C, Hoeger KM, López-Bermejo A, Ong K, Peña AS, Reinehr T, Santoro N, Tena-Sempere M, Tao R, Yildiz BO, Alkhayyat H, Deeb A, Joel D, Horikawa R, de Zegher F, Lee PA
Horm Res Paediatr 2017;88(6):371-395. Epub 2017 Nov 13 doi: 10.1159/000479371. PMID: 29156452
Büscher AK, Cetiner M, Büscher R, Wingen AM, Hauffa BP, Hoyer PF
Pediatr Nephrol 2012 Nov;27(11):2065-2071. Epub 2012 Jun 5 doi: 10.1007/s00467-012-2220-y. PMID: 22669322
Gill H, Mugo M, Whaley-Connell A, Stump C, Sowers JR
Am J Med Sci 2005 Dec;330(6):290-4. doi: 10.1097/00000441-200512000-00006. PMID: 16355013

Therapy

Nguyen MLT, Pham C, Pham VT, Nham PLT, Ta BT, Le DT, Le QV, Hoang XC, Bozko P, Nguyen LT, Bui KC
Cell Biochem Biophys 2024 Jun;82(2):687-695. Epub 2024 Jan 20 doi: 10.1007/s12013-024-01217-9. PMID: 38243102
Tural U, Iosifescu DV
Int J Eat Disord 2022 Oct;55(10):1279-1290. Epub 2022 Jun 11 doi: 10.1002/eat.23753. PMID: 35689560
Kanhai AA, Bange H, Verburg L, Dijkstra KL, Price LS, Peters DJM, Leonhard WN
Sci Rep 2020 Feb 3;10(1):1672. doi: 10.1038/s41598-020-58382-z. PMID: 32015419Free PMC Article
Garikapati KK, Ammu VVVRK, Krishnamurthy PT, Chintamaneni PK, Pindiprolu SKSS
Med Hypotheses 2019 May;126:78-81. Epub 2019 Mar 22 doi: 10.1016/j.mehy.2019.03.014. PMID: 31010504
Miyata M, Ikeda Y, Nakamura S, Sasaki T, Abe S, Minagoe S, Torii H, Lee S, Tateishi S, Kihara K, Ohba I, Kajiya S, Furusho Y, Hamasaki S, Tei C; Kagoshima Collaborate Trial in Metabolic Syndrome (KACT-MetS) Investigators
Circ J 2012;76(4):843-51. doi: 10.1253/circj.cj-12-0153. PMID: 22451451

Prognosis

Ali M, Kamran M, Talha M, Shad MU
BMC Psychiatry 2024 Jan 31;24(1):88. doi: 10.1186/s12888-024-05529-1. PMID: 38297246Free PMC Article
Nguyen MLT, Pham C, Pham VT, Nham PLT, Ta BT, Le DT, Le QV, Hoang XC, Bozko P, Nguyen LT, Bui KC
Cell Biochem Biophys 2024 Jun;82(2):687-695. Epub 2024 Jan 20 doi: 10.1007/s12013-024-01217-9. PMID: 38243102
Gutaj P, Sibiak R, Jankowski M, Awdi K, Bryl R, Mozdziak P, Kempisty B, Wender-Ozegowska E
Int J Mol Sci 2020 Dec 10;21(24) doi: 10.3390/ijms21249408. PMID: 33321877Free PMC Article
Adu-Gyamfi EA, Fondjo LA, Owiredu WKBA, Czika A, Nelson W, Lamptey J, Wang YX, Ding YB
Cell Biochem Funct 2020 Jan;38(1):106-117. Epub 2019 Nov 19 doi: 10.1002/cbf.3458. PMID: 31746004
Yap NY, Yap FN, Perumal K, Rajandram R
Biomarkers 2019 Sep;24(6):607-614. Epub 2019 Jul 2 doi: 10.1080/1354750X.2019.1634763. PMID: 31215811

Clinical prediction guides

Ali M, Kamran M, Talha M, Shad MU
BMC Psychiatry 2024 Jan 31;24(1):88. doi: 10.1186/s12888-024-05529-1. PMID: 38297246Free PMC Article
Kouvari M, Valenzuela-Vallejo L, Axarloglou E, Verrastro O, Papatheodoridis G, Mingrone G, George J, Mantzoros CS
Liver Int 2024 Mar;44(3):848-864. Epub 2024 Jan 23 doi: 10.1111/liv.15847. PMID: 38263703
Suzuki Y, Nakae H, Satoh K, Hirasawa N, Kameyama K, Irie Y, Kitamura T, Nara T, Maeno K, Yoshida K, Okuyama M
Ther Apher Dial 2023 Dec;27(6):1028-1034. Epub 2023 Aug 31 doi: 10.1111/1744-9987.14054. PMID: 37649446
Qian Y, Xia F, Zuo Y, Zhong M, Yang L, Jiang Y, Zou C
Orphanet J Rare Dis 2022 May 7;17(1):187. doi: 10.1186/s13023-022-02344-3. PMID: 35525976Free PMC Article
Gutaj P, Sibiak R, Jankowski M, Awdi K, Bryl R, Mozdziak P, Kempisty B, Wender-Ozegowska E
Int J Mol Sci 2020 Dec 10;21(24) doi: 10.3390/ijms21249408. PMID: 33321877Free PMC Article

Recent systematic reviews

Ali M, Kamran M, Talha M, Shad MU
BMC Psychiatry 2024 Jan 31;24(1):88. doi: 10.1186/s12888-024-05529-1. PMID: 38297246Free PMC Article
Yap NY, Yap FN, Perumal K, Rajandram R
Biomarkers 2019 Sep;24(6):607-614. Epub 2019 Jul 2 doi: 10.1080/1354750X.2019.1634763. PMID: 31215811
Costa RR, Buttelli ACK, Vieira AF, Coconcelli L, Magalhães RL, Delevatti RS, Kruel LFM
J Phys Act Health 2019 Jun 1;16(6):477-491. Epub 2019 Apr 25 doi: 10.1123/jpah.2018-0317. PMID: 31023184
Yu N, Ruan Y, Gao X, Sun J
Horm Metab Res 2017 Mar;49(3):164-173. Epub 2017 Mar 1 doi: 10.1055/s-0042-121605. PMID: 28249299
Bartoli F, Crocamo C, Clerici M, Carrà G
Eur Neuropsychopharmacol 2015 Oct;25(10):1767-74. Epub 2015 Jun 20 doi: 10.1016/j.euroneuro.2015.06.011. PMID: 26164075

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