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Cleft Maxilla

MedGen UID:
903416
•Concept ID:
C4086185
•
Congenital Abnormality

Definition

A congenital abnormality consisting of a fissure in the midline of the upper jawbone. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCleft Maxilla

Professional guidelines

PubMed

Cleft Lip and Palate Midfacial Hypoplasia: Criteria to Choose the Treatment.
Fariña R, Lolas J, Moreno E, Alister JP, Uribe MF, Pantoja R, Valladares S, Arrué C
J Craniofac Surg 2022 Mar-Apr 01;33(2):496-501. doi: 10.1097/SCS.0000000000007973. PMID: 34261964
Management of the protuberant premaxilla: where does it fit in?
Morris L
Curr Opin Otolaryngol Head Neck Surg 2019 Aug;27(4):302-309. doi: 10.1097/MOO.0000000000000558. PMID: 31219831
Management of the premaxilla in the treatment of bilateral cleft of lip and palate: what can the literature tell us?
Bittermann GK, de Ruiter AP, Janssen NG, Bittermann AJ, van der Molen AM, van Es RJ, Rosenberg AJ, Koole R
Clin Oral Investig 2016 Mar;20(2):207-17. Epub 2015 Sep 16 doi: 10.1007/s00784-015-1589-y. PMID: 26374747Free PMC Article

Recent clinical studies

Etiology

Effects of anterior maxillary distraction compared to LeFort-1 osteotomy and total maxillary distraction osteogenesis for treating hypoplastic maxilla in patients with cleft lip and palate- A systematic review and meta-analysis.
Kaur H, Grover S, Singaraju GS, Sidhu MS, Jaglan A, Dogra N
J Stomatol Oral Maxillofac Surg 2023 Feb;124(1S):101308. Epub 2022 Oct 8 doi: 10.1016/j.jormas.2022.10.007. PMID: 36220549
Skeletal stability of maxillary advancement with and without a mandibular reduction in the cleft lip and palate patient.
Wong FX, Heggie AA, Shand JM, Schneider PM
Int J Oral Maxillofac Surg 2016 Dec;45(12):1501-1507. Epub 2016 Aug 27 doi: 10.1016/j.ijom.2016.08.007. PMID: 27575393
Midfacial volumetric and upper lip soft tissue changes after Le Fort I advancement of the cleft maxilla.
Susarla SM, Berli JU, Kumar A
J Oral Maxillofac Surg 2015 Apr;73(4):708-18. Epub 2014 Nov 14 doi: 10.1016/j.joms.2014.10.033. PMID: 25649014
Advancement of the cleft maxilla using distraction osteogenesis--surgical and orthodontic considerations.
Aizenbud D, Hazan-Molina H, Emodi O, Rachmiel A
Alpha Omegan 2011 Fall-Winter;104(3-4):85-96. PMID: 22686104
Cleft maxillary distraction versus orthognathic surgery--which one is more stable in 5 years?
Chua HD, Hägg MB, Cheung LK
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010 Jun;109(6):803-14. Epub 2010 Mar 17 doi: 10.1016/j.tripleo.2009.10.056. PMID: 20299247

Diagnosis

Does angulation of osteotome during pterygomaxillary dysjunction for a Le Fort I osteotomy influence stress transmission to the orbit? A finite element simulation in normal and cleft maxillae.
Juliet M, Parameswaran A, Pedamally M, Aggarwal N, Ramanthan M, Mori Y
Br J Oral Maxillofac Surg 2021 May;59(4):407-412. Epub 2020 Aug 19 doi: 10.1016/j.bjoms.2020.08.031. PMID: 33771377

Therapy

Cleft maxillary distraction versus orthognathic surgery--which one is more stable in 5 years?
Chua HD, Hägg MB, Cheung LK
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010 Jun;109(6):803-14. Epub 2010 Mar 17 doi: 10.1016/j.tripleo.2009.10.056. PMID: 20299247
Experience with e-PTFE membrane application to bone grafting of cleft maxilla.
Piette E, Alberius P, Samman N, Linde A
Int J Oral Maxillofac Surg 1995 Oct;24(5):327-32. doi: 10.1016/s0901-5027(05)80483-7. PMID: 8627094

Prognosis

Skeletal stability of maxillary advancement with and without a mandibular reduction in the cleft lip and palate patient.
Wong FX, Heggie AA, Shand JM, Schneider PM
Int J Oral Maxillofac Surg 2016 Dec;45(12):1501-1507. Epub 2016 Aug 27 doi: 10.1016/j.ijom.2016.08.007. PMID: 27575393
Midfacial volumetric and upper lip soft tissue changes after Le Fort I advancement of the cleft maxilla.
Susarla SM, Berli JU, Kumar A
J Oral Maxillofac Surg 2015 Apr;73(4):708-18. Epub 2014 Nov 14 doi: 10.1016/j.joms.2014.10.033. PMID: 25649014
Cleft maxillary distraction versus orthognathic surgery--which one is more stable in 5 years?
Chua HD, Hägg MB, Cheung LK
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010 Jun;109(6):803-14. Epub 2010 Mar 17 doi: 10.1016/j.tripleo.2009.10.056. PMID: 20299247
Distraction osteogenesis of the cleft maxilla.
Wong GB, Ciminello FS, Padwa BL
Facial Plast Surg 2008 Nov;24(4):467-71. Epub 2008 Nov 25 doi: 10.1055/s-0028-1102910. PMID: 19034823
The stability of the downgrafted maxilla in the cleft lip and palate patient.
Macmillan AR, Tideman H
Ann R Australas Coll Dent Surg 1994 Apr;12:232-9. PMID: 7993054

Clinical prediction guides

Midfacial volumetric and upper lip soft tissue changes after Le Fort I advancement of the cleft maxilla.
Susarla SM, Berli JU, Kumar A
J Oral Maxillofac Surg 2015 Apr;73(4):708-18. Epub 2014 Nov 14 doi: 10.1016/j.joms.2014.10.033. PMID: 25649014
Distraction osteogenesis of the cleft maxilla.
Wong GB, Ciminello FS, Padwa BL
Facial Plast Surg 2008 Nov;24(4):467-71. Epub 2008 Nov 25 doi: 10.1055/s-0028-1102910. PMID: 19034823
Maxillary distraction for the management of cleft maxillary hypoplasia with a rigid external distraction system.
Figueroa AA, Polley JW, Ko EW
Semin Orthod 1999 Mar;5(1):46-51. doi: 10.1016/s1073-8746(99)80042-5. PMID: 10371940
The stability of the downgrafted maxilla in the cleft lip and palate patient.
Macmillan AR, Tideman H
Ann R Australas Coll Dent Surg 1994 Apr;12:232-9. PMID: 7993054
A roentgen stereophotogrammetric study of implant stability and movement of segments in the maxilla of infants with cleft lip and palate.
Rune B, Jacobsson S, Sarnäs KV, Selvik G
Cleft Palate J 1979 Jul;16(3):267-78. PMID: 287576

Recent systematic reviews

Effects of anterior maxillary distraction compared to LeFort-1 osteotomy and total maxillary distraction osteogenesis for treating hypoplastic maxilla in patients with cleft lip and palate- A systematic review and meta-analysis.
Kaur H, Grover S, Singaraju GS, Sidhu MS, Jaglan A, Dogra N
J Stomatol Oral Maxillofac Surg 2023 Feb;124(1S):101308. Epub 2022 Oct 8 doi: 10.1016/j.jormas.2022.10.007. PMID: 36220549

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