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Cutaneous adenocystic carcinoma

MedGen UID:
91071
•Concept ID:
C0346017
•
Neoplastic Process
Synonyms: adenoid cystic carcinoma of skin; adenoid cystic carcinoma of the skin; adenoid cystic cutaneous carcinoma; Adenoid cystic eccrine carcinoma; adenoid cystic eccrine carcinoma; adenoid cystic eccrine carcinoma (morphologic abnormality); adenoid cystic eccrine carcinoma of skin; adenoid cystic skin carcinoma; cutaneous adenocystic carcinoma; primary cutaneous adenocystic carcinoma; skin of body adenoid cystic carcinoma
SNOMED CT: Adenoid cystic eccrine carcinoma (399968001)
 
Monarch Initiative: MONDO:0003180

Definition

A adenoid cystic carcinoma that involves the skin of body. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCutaneous adenocystic carcinoma

Professional guidelines

PubMed

Cutaneous Sweat Gland Carcinomas with Basaloid Differentiation: An Update with Emphasis on Differential Diagnoses.
Flux K, Brenn T
Clin Lab Med 2017 Sep;37(3):587-601. Epub 2017 Jun 9 doi: 10.1016/j.cll.2017.05.006. PMID: 28802502
Antibodies to intermediate filament proteins. The differential diagnosis of cutaneous tumors.
Miettinen M, Lehto VP, Virtanen I
Arch Dermatol 1985 Jun;121(6):736-41. PMID: 2408582

Recent clinical studies

Etiology

Systematic pan-cancer analyses of the potential function of the Golgi scaffold protein PAQR3.
Ling ZN, Hong LL, Wu J, Ling ZQ
Sci Rep 2024 Feb 6;14(1):3030. doi: 10.1038/s41598-024-53489-z. PMID: 38321173Free PMC Article
Spiradenoma With Adenoid Cystic Carcinoma-Like Features.
Hopkins C, Moyer A, Huttenbach YT
Am J Dermatopathol 2020 Jun;42(6):442-445. doi: 10.1097/DAD.0000000000001594. PMID: 31855584
Diverse presentations of cutaneous mosaicism occur in CYLD cutaneous syndrome and may result in parent-to-child transmission.
Arefi M, Wilson V, Muthiah S, Zwolinski S, Bajwa D, Brennan P, Blasdale K, Bourn D, Burn J, Santibanez-Koref M, Rajan N
J Am Acad Dermatol 2019 Dec;81(6):1300-1307. Epub 2019 May 11 doi: 10.1016/j.jaad.2019.05.021. PMID: 31085270Free PMC Article
Cutaneous Adenoid Cystic Carcinoma with Perineural Invasion Diagnosed in the Foot: A Case Report.
Agunbiade M, Lalehparvar S, Khaladj M
J Am Podiatr Med Assoc 2017 Sep;107(5):457-460. Epub 2017 May 22 doi: 10.7547/16-091. PMID: 28530493
Primary cutaneous adenoid cystic carcinoma with distant metastasis: a case report and brief literature review.
Singh A, Ramesh V
Indian J Dermatol Venereol Leprol 2010 Mar-Apr;76(2):176-9. doi: 10.4103/0378-6323.60573. PMID: 20228549

Diagnosis

Cutaneous Adenoid Cystic Carcinoma.
Schembri-Wismayer D, Gupta S, Erickson LA
Mayo Clin Proc 2024 Jun;99(6):1017-1018. doi: 10.1016/j.mayocp.2024.02.029. PMID: 38839182
Malignant Sweat Gland Tumors.
Ahn CS, Sangüeza OP
Hematol Oncol Clin North Am 2019 Feb;33(1):53-71. doi: 10.1016/j.hoc.2018.09.002. PMID: 30497677
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149
Cylindroma: an update.
Jordão C, de Magalhães TC, Cuzzi T, Ramos-e-Silva M
Int J Dermatol 2015 Mar;54(3):275-8. Epub 2014 Dec 16 doi: 10.1111/ijd.12600. PMID: 25515269
Brooke-Spiegler syndrome.
Kim C, Kovich OI, Dosik J
Dermatol Online J 2007 Jan 27;13(1):10. PMID: 17511943

Therapy

Effectiveness and tolerance of electrochemotherapy as palliative therapy for patients with head and neck cancer and malignant melanoma and its relation to early skin reaction.
Caballero-Borrego M, Coll S, Navarrete P
Braz J Otorhinolaryngol 2024 Jan-Feb;90(1):101365. Epub 2023 Nov 22 doi: 10.1016/j.bjorl.2023.101365. PMID: 38006727Free PMC Article
The DAHANCA 32 study: Electrochemotherapy for recurrent mucosal head and neck cancer.
Plaschke CC, Johannesen HH, Hansen RH, Hendel HW, Kiss K, Gehl J, Wessel I
Head Neck 2019 Feb;41(2):329-339. Epub 2018 Dec 15 doi: 10.1002/hed.25454. PMID: 30552847
Change of Circulating and Tissue-Based miR-20a in Human Cancers and Associated Prognostic Implication: A Systematic Review and Meta-Analysis.
Zhang Q, Wang Q, Sun W, Gao F, Liu L, Cheng L, Li Z
Biomed Res Int 2018;2018:6124927. Epub 2018 Nov 25 doi: 10.1155/2018/6124927. PMID: 30596096Free PMC Article
Reirradiation of Recurrent and Second Primary Head and Neck Cancer With Proton Therapy.
McDonald MW, Zolali-Meybodi O, Lehnert SJ, Estabrook NC, Liu Y, Cohen-Gadol AA, Moore MG
Int J Radiat Oncol Biol Phys 2016 Nov 15;96(4):808-819. Epub 2016 Aug 3 doi: 10.1016/j.ijrobp.2016.07.037. PMID: 27788954
Molecular pathology of skin neoplasms of the head and neck.
Kraft S, Granter SR
Arch Pathol Lab Med 2014 Jun;138(6):759-87. doi: 10.5858/arpa.2013-0157-RA. PMID: 24878016

Prognosis

Systematic pan-cancer analyses of the potential function of the Golgi scaffold protein PAQR3.
Ling ZN, Hong LL, Wu J, Ling ZQ
Sci Rep 2024 Feb 6;14(1):3030. doi: 10.1038/s41598-024-53489-z. PMID: 38321173Free PMC Article
Incidence and trends of cutaneous adnexal tumors in the United States in 2000-2018: A population-based study.
Gibbs DC, Yeung H, Blalock TW
J Am Acad Dermatol 2023 Jan;88(1):226-228. Epub 2022 May 4 doi: 10.1016/j.jaad.2022.04.052. PMID: 35525505Free PMC Article
Diverse presentations of cutaneous mosaicism occur in CYLD cutaneous syndrome and may result in parent-to-child transmission.
Arefi M, Wilson V, Muthiah S, Zwolinski S, Bajwa D, Brennan P, Blasdale K, Bourn D, Burn J, Santibanez-Koref M, Rajan N
J Am Acad Dermatol 2019 Dec;81(6):1300-1307. Epub 2019 May 11 doi: 10.1016/j.jaad.2019.05.021. PMID: 31085270Free PMC Article
Primary cutaneous adenoid cystic carcinoma with distant metastasis: a case report and brief literature review.
Singh A, Ramesh V
Indian J Dermatol Venereol Leprol 2010 Mar-Apr;76(2):176-9. doi: 10.4103/0378-6323.60573. PMID: 20228549
Perineural tumor spread.
Maroldi R, Farina D, Borghesi A, Marconi A, Gatti E
Neuroimaging Clin N Am 2008 May;18(2):413-29, xi. doi: 10.1016/j.nic.2008.01.001. PMID: 18466839

Clinical prediction guides

Basal cell carcinoma: Histopathological gamut.
Sharma P, Wadhwan V, Bansal V
Indian J Dent Res 2021 Jul-Sep;32(3):407-410. doi: 10.4103/ijdr.IJDR_227_19. PMID: 35229784
Change of Circulating and Tissue-Based miR-20a in Human Cancers and Associated Prognostic Implication: A Systematic Review and Meta-Analysis.
Zhang Q, Wang Q, Sun W, Gao F, Liu L, Cheng L, Li Z
Biomed Res Int 2018;2018:6124927. Epub 2018 Nov 25 doi: 10.1155/2018/6124927. PMID: 30596096Free PMC Article
Dermoscopy of Adnexal Tumors.
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149
Transition from cylindroma to spiradenoma in CYLD-defective tumours is associated with reduced DKK2 expression.
Rajan N, Burn J, Langtry J, Sieber-Blum M, Lord CJ, Ashworth A
J Pathol 2011 Jul;224(3):309-21. Epub 2011 May 19 doi: 10.1002/path.2896. PMID: 21598248
Malignant transformation of eccrine spiradenoma.
Cooper PH, Frierson HF Jr, Morrison AG
Arch Dermatol 1985 Nov;121(11):1445-8. PMID: 2996443

Recent systematic reviews

Change of Circulating and Tissue-Based miR-20a in Human Cancers and Associated Prognostic Implication: A Systematic Review and Meta-Analysis.
Zhang Q, Wang Q, Sun W, Gao F, Liu L, Cheng L, Li Z
Biomed Res Int 2018;2018:6124927. Epub 2018 Nov 25 doi: 10.1155/2018/6124927. PMID: 30596096Free PMC Article
Cylindroma of head and neck: review of the literature and report of two rare cases.
Singh DD, Naujoks C, Depprich R, Schulte KW, Jankowiak F, Kübler NR, Handschel J
J Craniomaxillofac Surg 2013 Sep;41(6):516-21. Epub 2012 Dec 21 doi: 10.1016/j.jcms.2012.11.016. PMID: 23260808

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