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Broad Ligament Serous Adenocarcinoma

MedGen UID:
927441
•Concept ID:
C4289909
•
Neoplastic Process
Synonym: High-Grade Broad Ligament Serous Adenocarcinoma

Definition

A rare serous adenocarcinoma that arises from the broad ligament. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBroad Ligament Serous Adenocarcinoma

Recent clinical studies

Etiology

Ependymomas of the central nervous system and adult extra-axial ependymomas are morphologically and immunohistochemically distinct--a comparative study with assessment of ovarian carcinomas for expression of glial fibrillary acidic protein.
Idowu MO, Rosenblum MK, Wei XJ, Edgar MA, Soslow RA
Am J Surg Pathol 2008 May;32(5):710-8. doi: 10.1097/PAS.0b013e318159a2b4. PMID: 18360284

Diagnosis

Rare Primary Adenocarcinoma of the Broad Ligament: Report of Two Cases and a Literature Review.
Miyoshi A, Miyatake T, Hara T, Komiya S, Komura N, Tanaka A, Kanao S, Takeda M, Mimura M, Nagamatsu M, Yamasaki M, Yokoi T
Int J Surg Pathol 2016 Aug;24(5):436-42. Epub 2015 Dec 23 doi: 10.1177/1066896915622690. PMID: 26699941
High-grade broad ligament cancer of müllerian origin: immunohistochemical analysis of a case and review of the literature.
Handa Y, Kato H, Kaneuchi M, Saitoh Y, Yamashita K
Int J Gynecol Cancer 2007 May-Jun;17(3):705-9. doi: 10.1111/j.1525-1438.2007.00843.x. PMID: 17504384
Primary papillary serous cystadenocarcinoma of broad ligament.
Nagar YS, Singh S, Sawlani V, Pal L, Dimri K, Lal P
Australas Radiol 2005 Apr;49(2):160-2. doi: 10.1111/j.1440-1673.2005.01365.x. PMID: 15845057
Malignant epithelial tumor of unknown origin of the broad ligament.
Itani Y, Itoh K, Adachi S, Koyama M, Kimura T, Chin R, Takemura T
Arch Gynecol Obstet 2002 Dec;267(2):113-6. doi: 10.1007/s00404-001-0264-5. PMID: 12439561
Paramesonephric papillary serous cystadenocarcinoma: a case report with scanning electron microscopy.
Stapleton JJ, Haber MH, Lindner LE
Acta Cytol 1981 May-Jun;25(3):310-6. PMID: 6942626

Therapy

Primary papillary serous cystadenocarcinoma of broad ligament.
Nagar YS, Singh S, Sawlani V, Pal L, Dimri K, Lal P
Australas Radiol 2005 Apr;49(2):160-2. doi: 10.1111/j.1440-1673.2005.01365.x. PMID: 15845057

Prognosis

Malignant mixed Mullerian tumor of broad ligament with synchronous ovarian and endometrial carcinoma: a rare association.
Arora P, Rao S, Khurana N, Talwar D, Tanwar R
J Cancer Res Ther 2011 Jan-Mar;7(1):88-91. doi: 10.4103/0973-1482.80460. PMID: 21546752
Malignant epithelial tumor of unknown origin of the broad ligament.
Itani Y, Itoh K, Adachi S, Koyama M, Kimura T, Chin R, Takemura T
Arch Gynecol Obstet 2002 Dec;267(2):113-6. doi: 10.1007/s00404-001-0264-5. PMID: 12439561
Papillary cystadenocarcinoma arising in a paratubal mesothelial cyst of the mesosalpinx--a case report.
Narurkar SD, Buch AC, Patel KD, Avasare SS, Niyogi GM
Indian J Cancer 2001 Jun-Dec;38(2-4):137-42. PMID: 12593453
The Brenner tumor: a clinicopathologic review.
Balasa RW, Adcock LL, Prem KA, Dehner LP
Obstet Gynecol 1977 Jul;50(1):120-8. PMID: 195239

Clinical prediction guides

Ependymomas of the central nervous system and adult extra-axial ependymomas are morphologically and immunohistochemically distinct--a comparative study with assessment of ovarian carcinomas for expression of glial fibrillary acidic protein.
Idowu MO, Rosenblum MK, Wei XJ, Edgar MA, Soslow RA
Am J Surg Pathol 2008 May;32(5):710-8. doi: 10.1097/PAS.0b013e318159a2b4. PMID: 18360284

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