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Pharyngeal stenosis

MedGen UID:
96001
•Concept ID:
C0396006
•
Disease or Syndrome
Synonyms: Pharyngeal Stenosis; Pharyngeal stricture
SNOMED CT: Pharyngeal stricture (232408005); Pharyngeal stenosis (232408005)

Definition

Narrowing of the pharyngeal airway. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPharyngeal stenosis

Professional guidelines

PubMed

Evolution of chronic dysphagia following treatment for head and neck cancer.
Nguyen NP, Moltz CC, Frank C, Vos P, Smith HJ, Karlsson U, Nguyen LM, Rose S, Dutta S, Sallah S
Oral Oncol 2006 Apr;42(4):374-80. Epub 2005 Nov 28 doi: 10.1016/j.oraloncology.2005.09.003. PMID: 16314138
Post laryngectomy complications and their mode of management--an analysis of 203 cases.
Verma A, Panda NK, Mehta S, Mann SB, Mehra YN
Indian J Cancer 1989 Dec;26(4):247-54. PMID: 2636211

Recent clinical studies

Etiology

National epidemiological survey on pharyngeal, laryngeal, and tracheal stenosis in Japan: A national survey on airway stenosis.
Kishimoto Y, Mizuno K, Kawai Y, Mizuno K, Hirabayashi H, Furukawa K, Morimoto N, Maeda K, Kaneko K, Omori K
Auris Nasus Larynx 2024 Dec;51(6):911-916. Epub 2024 Sep 11 doi: 10.1016/j.anl.2024.08.008. PMID: 39265196
Salivary bypass tube in total laryngectomy: Systematic review and meta-analysis.
Costantino A, Pace GM, Festa BM, Ferreli F, Malvezzi L, Spriano G, Mercante G, De Virgilio A
Head Neck 2022 Nov;44(11):2608-2620. Epub 2022 Aug 3 doi: 10.1002/hed.27169. PMID: 35920404
Pharyngeal reconstruction for severe pharyngeal stenosis in Behçet's disease: a retrospective case series.
Gu W, Jin X, Wang J
Clin Exp Rheumatol 2022 Sep;40(8):1554-1559. Epub 2022 Aug 2 doi: 10.55563/clinexprheumatol/iec6ff. PMID: 35916295
Case report: pharyngolaryngeal stenosis in a child due to caustic ingestion treated with transoral CO2 laser microsurgery.
Berlucchi M, Barbieri D, Garofolo S, Stefini S, Peretti G
Ann Otol Rhinol Laryngol 2014 Dec;123(12):847-51. Epub 2014 Jun 18 doi: 10.1177/0003489414538938. PMID: 24944275
Radial forearm versus anterolateral thigh free flaps for laryngopharyngectomy defects: prospective, randomized trial.
Morrissey AT, O'Connell DA, Garg S, Seikaly H, Harris JR
J Otolaryngol Head Neck Surg 2010 Aug;39(4):448-53. PMID: 20643014

Diagnosis

National epidemiological survey on pharyngeal, laryngeal, and tracheal stenosis in Japan: A national survey on airway stenosis.
Kishimoto Y, Mizuno K, Kawai Y, Mizuno K, Hirabayashi H, Furukawa K, Morimoto N, Maeda K, Kaneko K, Omori K
Auris Nasus Larynx 2024 Dec;51(6):911-916. Epub 2024 Sep 11 doi: 10.1016/j.anl.2024.08.008. PMID: 39265196
Pharyngeal reconstruction for severe pharyngeal stenosis in Behçet's disease: a retrospective case series.
Gu W, Jin X, Wang J
Clin Exp Rheumatol 2022 Sep;40(8):1554-1559. Epub 2022 Aug 2 doi: 10.55563/clinexprheumatol/iec6ff. PMID: 35916295
Endoscopic submucosal dissection through a gastrostomy for early gastric cancer in patients with pharyngeal stenosis.
Kitamura S, Muguruma N, Okamoto K, Nakamura F, Okada Y, Kimura T, Miyamoto H, Takayama T
Gastrointest Endosc 2014 Feb;79(2):206-7. Epub 2013 Oct 12 doi: 10.1016/j.gie.2013.09.018. PMID: 24129250
An uncommon shape of epiglottis misleading as acute epiglottitis.
Sasaki T, Nomura Y, Tsunoda K
BMJ Case Rep 2012 Jul 27;2012 doi: 10.1136/bcr-02-2012-5760. PMID: 22847561Free PMC Article
Endoscopic classification of pharyngeal stenosis pattern in obstructive sleep apnea hypopnea syndrome.
Higami S, Inoue Y, Higami Y, Takeuchi H, Ikoma H
Psychiatry Clin Neurosci 2002 Jun;56(3):317-8. doi: 10.1046/j.1440-1819.2002.00960.x. PMID: 12047613

Therapy

Salivary bypass tube in total laryngectomy: Systematic review and meta-analysis.
Costantino A, Pace GM, Festa BM, Ferreli F, Malvezzi L, Spriano G, Mercante G, De Virgilio A
Head Neck 2022 Nov;44(11):2608-2620. Epub 2022 Aug 3 doi: 10.1002/hed.27169. PMID: 35920404
Case report: pharyngolaryngeal stenosis in a child due to caustic ingestion treated with transoral CO2 laser microsurgery.
Berlucchi M, Barbieri D, Garofolo S, Stefini S, Peretti G
Ann Otol Rhinol Laryngol 2014 Dec;123(12):847-51. Epub 2014 Jun 18 doi: 10.1177/0003489414538938. PMID: 24944275
An uncommon shape of epiglottis misleading as acute epiglottitis.
Sasaki T, Nomura Y, Tsunoda K
BMJ Case Rep 2012 Jul 27;2012 doi: 10.1136/bcr-02-2012-5760. PMID: 22847561Free PMC Article
Radial forearm versus anterolateral thigh free flaps for laryngopharyngectomy defects: prospective, randomized trial.
Morrissey AT, O'Connell DA, Garg S, Seikaly H, Harris JR
J Otolaryngol Head Neck Surg 2010 Aug;39(4):448-53. PMID: 20643014
Severe pharyngeal stenosis after caustic ingestion.
Goldfarb A, Gross M, Sichel JY, Eliashar R
Isr Med Assoc J 2002 Apr;4(4):305. PMID: 12001713

Prognosis

Dilation after laryngectomy: Incidence, risk factors and complications.
Petersen JF, Pézier TF, van Dieren JM, van der Noort V, van Putten T, Bril SI, Janssen L, Dirven R, van den Brekel MWM, de Bree R
Oral Oncol 2019 Apr;91:107-112. Epub 2019 Mar 6 doi: 10.1016/j.oraloncology.2019.02.025. PMID: 30926055
Radial forearm versus anterolateral thigh free flaps for laryngopharyngectomy defects: prospective, randomized trial.
Morrissey AT, O'Connell DA, Garg S, Seikaly H, Harris JR
J Otolaryngol Head Neck Surg 2010 Aug;39(4):448-53. PMID: 20643014
Reconstruction for postcricoid pharyngeal stenosis after organ preservation protocols.
Delaere P, Hierner R, Goeleven A, D'Hoore A
Laryngoscope 2006 Mar;116(3):502-4. doi: 10.1097/01.mlg.0000194224.37329.c3. PMID: 16540919
Long-term follow-up and mechanisms of obstructive sleep apnea (OSA) and related syndromes through infancy and childhood.
Contencin P, Guilleminault C, Manach Y
Int J Pediatr Otorhinolaryngol 2003 Dec;67 Suppl 1:S119-23. doi: 10.1016/j.ijporl.2003.08.009. PMID: 14662182
Severe pharyngeal stenosis treated with inferiorly based sternocleidomastoid myocutaneous flap.
Haller JR, Gray SD
Ann Otol Rhinol Laryngol 1999 Aug;108(8):731-4. doi: 10.1177/000348949910800803. PMID: 10453778

Clinical prediction guides

Pharyngeal reconstruction for severe pharyngeal stenosis in Behçet's disease: a retrospective case series.
Gu W, Jin X, Wang J
Clin Exp Rheumatol 2022 Sep;40(8):1554-1559. Epub 2022 Aug 2 doi: 10.55563/clinexprheumatol/iec6ff. PMID: 35916295
Scar contracture prevention with local steroid injections in transoral videolaryngoscopic surgery.
Uno K, Tomifuji M, Araki K, Tanaka S, Taniai S, Tanaka Y, Kimura E, Ogawa K, Shiotani A
Auris Nasus Larynx 2020 Oct;47(5):856-863. Epub 2020 Feb 24 doi: 10.1016/j.anl.2020.02.007. PMID: 32107068
Dilation after laryngectomy: Incidence, risk factors and complications.
Petersen JF, Pézier TF, van Dieren JM, van der Noort V, van Putten T, Bril SI, Janssen L, Dirven R, van den Brekel MWM, de Bree R
Oral Oncol 2019 Apr;91:107-112. Epub 2019 Mar 6 doi: 10.1016/j.oraloncology.2019.02.025. PMID: 30926055
Case report: pharyngolaryngeal stenosis in a child due to caustic ingestion treated with transoral CO2 laser microsurgery.
Berlucchi M, Barbieri D, Garofolo S, Stefini S, Peretti G
Ann Otol Rhinol Laryngol 2014 Dec;123(12):847-51. Epub 2014 Jun 18 doi: 10.1177/0003489414538938. PMID: 24944275
An uncommon shape of epiglottis misleading as acute epiglottitis.
Sasaki T, Nomura Y, Tsunoda K
BMJ Case Rep 2012 Jul 27;2012 doi: 10.1136/bcr-02-2012-5760. PMID: 22847561Free PMC Article

Recent systematic reviews

Salivary bypass tube in total laryngectomy: Systematic review and meta-analysis.
Costantino A, Pace GM, Festa BM, Ferreli F, Malvezzi L, Spriano G, Mercante G, De Virgilio A
Head Neck 2022 Nov;44(11):2608-2620. Epub 2022 Aug 3 doi: 10.1002/hed.27169. PMID: 35920404

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