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Microscopic nephrocalcinosis

MedGen UID:
98014
•Concept ID:
C0403474
•
Disease or Syndrome
SNOMED CT: Microscopic nephrocalcinosis (236444003)
 
HPO: HP:0008327

Definition

The presence of microscopic crystalline calcium precipitates in the form of oxalate and/or phosphate in the renal parenchyma. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMicroscopic nephrocalcinosis

Professional guidelines

PubMed

Phosphate treatment of hypercalcaemia due to carcinoma.
Thalassinos N, Joplin GF
Br Med J 1968 Oct 5;4(5622):14-9. doi: 10.1136/bmj.4.5622.14. PMID: 4175670Free PMC Article

Recent clinical studies

Etiology

Microscopic nephrocalcinosis in chronic kidney disease patients.
Evenepoel P, Daenen K, Bammens B, Claes K, Meijers B, Naesens M, Sprangers B, Kuypers D, Lerut E
Nephrol Dial Transplant 2015 May;30(5):843-8. Epub 2015 Jan 13 doi: 10.1093/ndt/gfu400. PMID: 25586405
Calcium levels as a risk factor for delayed graft function.
Boom H, Mallat MJ, de Fijter JW, Paul LC, Bruijn JA, van Es LA
Transplantation 2004 Mar 27;77(6):868-73. doi: 10.1097/01.tp.0000116417.03114.87. PMID: 15077029
Microscopic nephrocalcinosis and hypercalciuria in nephrotic syndrome.
Mocan H, Yildiran A, Camlibel T, Kuzey GM
Hum Pathol 2000 Nov;31(11):1363-7. PMID: 11112210
Immunoreactive calmodulin in cystic fibrosis kidneys.
Couper R, Bentur L, Kilbourn JP, Wolf P
Aust N Z J Med 1993 Oct;23(5):484-8. doi: 10.1111/j.1445-5994.1993.tb01834.x. PMID: 8297278

Diagnosis

Renal calcification in the first year of life.
Karlowicz MG, Adelman RD
Pediatr Clin North Am 1995 Dec;42(6):1397-413. doi: 10.1016/s0031-3955(16)40090-8. PMID: 8614592

Therapy

Microscopic nephrocalcinosis and hypercalciuria in nephrotic syndrome.
Mocan H, Yildiran A, Camlibel T, Kuzey GM
Hum Pathol 2000 Nov;31(11):1363-7. PMID: 11112210

Prognosis

Microscopic nephrocalcinosis in chronic kidney disease patients.
Evenepoel P, Daenen K, Bammens B, Claes K, Meijers B, Naesens M, Sprangers B, Kuypers D, Lerut E
Nephrol Dial Transplant 2015 May;30(5):843-8. Epub 2015 Jan 13 doi: 10.1093/ndt/gfu400. PMID: 25586405

Clinical prediction guides

Microscopic nephrocalcinosis in chronic kidney disease patients.
Evenepoel P, Daenen K, Bammens B, Claes K, Meijers B, Naesens M, Sprangers B, Kuypers D, Lerut E
Nephrol Dial Transplant 2015 May;30(5):843-8. Epub 2015 Jan 13 doi: 10.1093/ndt/gfu400. PMID: 25586405
Microscopic nephrocalcinosis in cystic fibrosis.
Katz SM, Krueger LJ, Falkner B
N Engl J Med 1988 Aug 4;319(5):263-6. doi: 10.1056/NEJM198808043190502. PMID: 3393180

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