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Uncomplicated Hypertension

MedGen UID:
99228
Concept ID:
C0497248
Disease or Syndrome

Definition

A condition of high blood pressure without resulting clinical disorders. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUncomplicated Hypertension

Professional guidelines

PubMed

Ona DID, Jimeno CA, Jasul GV Jr, Bunyi MLE, Oliva R, Gonzalez-Santos LE, Mercado-Asis LB, Luz VA, Leus AG, Diaz ABF, Santos MI, Belen AA, Bonzon DD, Bote-Nunez J, Cawed-Mende RMN, Chua AS, Javier AMJT, Juangco DNA, Madrigal-Dy C, Manicad MB, Ortiz JMGR, Padolina CS, Sison MCC, Villanueva NJ
J Clin Hypertens (Greenwich) 2021 Sep;23(9):1637-1650. Epub 2021 Aug 3 doi: 10.1111/jch.14335. PMID: 34343391Free PMC Article
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. National Heart, Lung, and Blood Institute; National High Blood Pressure Education Program Coordinating Committee
Hypertension 2003 Dec;42(6):1206-52. Epub 2003 Dec 1 doi: 10.1161/01.HYP.0000107251.49515.c2. PMID: 14656957
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee
JAMA 2003 May 21;289(19):2560-72. Epub 2003 May 14 doi: 10.1001/jama.289.19.2560. PMID: 12748199

Recent clinical studies

Etiology

Ona DID, Jimeno CA, Jasul GV Jr, Bunyi MLE, Oliva R, Gonzalez-Santos LE, Mercado-Asis LB, Luz VA, Leus AG, Diaz ABF, Santos MI, Belen AA, Bonzon DD, Bote-Nunez J, Cawed-Mende RMN, Chua AS, Javier AMJT, Juangco DNA, Madrigal-Dy C, Manicad MB, Ortiz JMGR, Padolina CS, Sison MCC, Villanueva NJ
J Clin Hypertens (Greenwich) 2021 Sep;23(9):1637-1650. Epub 2021 Aug 3 doi: 10.1111/jch.14335. PMID: 34343391Free PMC Article
Sirtori CR, Arnoldi A, Cicero AF
Ann Med 2015;47(6):447-56. Epub 2015 Sep 11 doi: 10.3109/07853890.2015.1078905. PMID: 26362125
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. National Heart, Lung, and Blood Institute; National High Blood Pressure Education Program Coordinating Committee
Hypertension 2003 Dec;42(6):1206-52. Epub 2003 Dec 1 doi: 10.1161/01.HYP.0000107251.49515.c2. PMID: 14656957
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee
JAMA 2003 May 21;289(19):2560-72. Epub 2003 May 14 doi: 10.1001/jama.289.19.2560. PMID: 12748199
Pickering TG
Cardiol Clin 1987 May;5(2):311-8. PMID: 3555801

Diagnosis

Garg A, Geissbühler Y, Houchen E, Choudhary N, Arora D, Vellanki V, Srivastava A, Priyanka, Darcy J 2nd, Richardson C, Kimball AB
Am J Clin Dermatol 2023 Nov;24(6):977-990. Epub 2023 Jun 28 doi: 10.1007/s40257-023-00796-2. PMID: 37378875Free PMC Article
Ona DID, Jimeno CA, Jasul GV Jr, Bunyi MLE, Oliva R, Gonzalez-Santos LE, Mercado-Asis LB, Luz VA, Leus AG, Diaz ABF, Santos MI, Belen AA, Bonzon DD, Bote-Nunez J, Cawed-Mende RMN, Chua AS, Javier AMJT, Juangco DNA, Madrigal-Dy C, Manicad MB, Ortiz JMGR, Padolina CS, Sison MCC, Villanueva NJ
J Clin Hypertens (Greenwich) 2021 Sep;23(9):1637-1650. Epub 2021 Aug 3 doi: 10.1111/jch.14335. PMID: 34343391Free PMC Article
De Caterina AR, Leone AM
Am J Cardiol 2010 May 15;105(10):1433-8. Epub 2010 Mar 30 doi: 10.1016/j.amjcard.2009.12.068. PMID: 20451690
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. National Heart, Lung, and Blood Institute; National High Blood Pressure Education Program Coordinating Committee
Hypertension 2003 Dec;42(6):1206-52. Epub 2003 Dec 1 doi: 10.1161/01.HYP.0000107251.49515.c2. PMID: 14656957
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee
JAMA 2003 May 21;289(19):2560-72. Epub 2003 May 14 doi: 10.1001/jama.289.19.2560. PMID: 12748199

Therapy

Argulian E, Bangalore S, Messerli FH
Am J Med 2019 Jul;132(7):816-819. Epub 2019 Feb 25 doi: 10.1016/j.amjmed.2019.01.039. PMID: 30817899
de Boer RA, Voors AA, van Veldhuisen DJ
Expert Opin Pharmacother 2007 Jul;8(10):1539-50. doi: 10.1517/14656566.8.10.1539. PMID: 17661735
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. National Heart, Lung, and Blood Institute; National High Blood Pressure Education Program Coordinating Committee
Hypertension 2003 Dec;42(6):1206-52. Epub 2003 Dec 1 doi: 10.1161/01.HYP.0000107251.49515.c2. PMID: 14656957
Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee
JAMA 2003 May 21;289(19):2560-72. Epub 2003 May 14 doi: 10.1001/jama.289.19.2560. PMID: 12748199
Pickering TG
Cardiol Clin 1987 May;5(2):311-8. PMID: 3555801

Prognosis

De Caterina AR, Leone AM
Am J Cardiol 2010 May 15;105(10):1433-8. Epub 2010 Mar 30 doi: 10.1016/j.amjcard.2009.12.068. PMID: 20451690
Kola LD, Sumaili EK, Krzesinski JM
Acta Clin Belg 2009 Nov-Dec;64(6):466-76. doi: 10.1179/acb.2009.082. PMID: 20101869
Ferdinand KC
J Clin Hypertens (Greenwich) 2008 May;10(5):382-9. doi: 10.1111/j.1751-7176.2008.07918.x. PMID: 18453798Free PMC Article
Pickering TG, Kario K
Curr Opin Nephrol Hypertens 2001 Sep;10(5):611-6. doi: 10.1097/00041552-200109000-00010. PMID: 11496054
McInnes GT
J Hypertens Suppl 1995 Aug;13(2):S49-56. doi: 10.1097/00004872-199508001-00008. PMID: 8576788

Clinical prediction guides

Phillips RA
Methodist Debakey Cardiovasc J 2015 Oct-Dec;11(4):206-13. doi: 10.14797/mdcj-11-4-206. PMID: 27057288Free PMC Article
De Caterina AR, Leone AM
Am J Cardiol 2010 May 15;105(10):1433-8. Epub 2010 Mar 30 doi: 10.1016/j.amjcard.2009.12.068. PMID: 20451690
Kola LD, Sumaili EK, Krzesinski JM
Acta Clin Belg 2009 Nov-Dec;64(6):466-76. doi: 10.1179/acb.2009.082. PMID: 20101869
Pickering TG, Kario K
Curr Opin Nephrol Hypertens 2001 Sep;10(5):611-6. doi: 10.1097/00041552-200109000-00010. PMID: 11496054
McInnes GT
J Hypertens Suppl 1995 Aug;13(2):S49-56. doi: 10.1097/00004872-199508001-00008. PMID: 8576788

Recent systematic reviews

Gnugesser E, Chwila C, Brenner S, Deckert A, Dambach P, Steinert JI, Bärnighausen T, Horstick O, Antia K, Louis VR
BMC Public Health 2022 Aug 8;22(1):1507. doi: 10.1186/s12889-022-13877-4. PMID: 35941626Free PMC Article
Loader J, Taylor FC, Lampa E, Sundström J
J Am Heart Assoc 2022 Jun 7;11(11):e025289. Epub 2022 May 27 doi: 10.1161/JAHA.122.025289. PMID: 35624081Free PMC Article
Akinlua JT, Meakin R, Fadahunsi P, Freemantle N
PLoS One 2016;11(5):e0154287. Epub 2016 May 5 doi: 10.1371/journal.pone.0154287. PMID: 27148880Free PMC Article
Alhawassi TM, Krass I, Pont LG
J Clin Hypertens (Greenwich) 2015 Jun;17(6):486-92. Epub 2015 Mar 31 doi: 10.1111/jch.12536. PMID: 25827023Free PMC Article
Marshall IJ, Wolfe CD, McKevitt C
BMJ 2012 Jul 9;345:e3953. doi: 10.1136/bmj.e3953. PMID: 22777025Free PMC Article

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