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Spindle cell sarcoma

MedGen UID:
64477
Concept ID:
C0205945
Neoplastic Process
Synonyms: Sarcoma, Spindle Cell; Sarcomas, Spindle Cell; Spindle Cell Sarcoma; Spindle Cell Sarcomas
SNOMED CT: Spindle cell sarcoma (9801004)
 
Monarch Initiative: MONDO:0002927

Definition

A malignant mesenchymal neoplasm composed of spindle-shaped cells. This is a morphologic term which can be applied to a wide range of sarcomas. [from NCI]

Professional guidelines

PubMed

Thway K, Fisher C
Semin Diagn Pathol 2021 Nov;38(6):170-186. Epub 2021 Sep 29 doi: 10.1053/j.semdp.2021.09.005. PMID: 34602314
Lee Y, Kim HJ, Yoon H, Choi CM, Oh YM, Lee SD, Lim CM, Kim WS, Koh Y, Lee JS
J Korean Med Sci 2016 Nov;31(11):1755-1760. doi: 10.3346/jkms.2016.31.11.1755. PMID: 27709853Free PMC Article
Goldstein JA, Cates JM
Adv Anat Pathol 2015 Jul;22(4):260-6. doi: 10.1097/PAP.0000000000000077. PMID: 26050263

Recent clinical studies

Etiology

Koshyk O, Dehner CA, van den Hout MFCM, Bempt IV, Sciot R, Huang HY, Agaimy A, Din NU, Klubíčková N, Mosaieby E, Skálová A, Michalová K, Schöffski P, Oliveira AM, Halling KC, Gupta S, Gross JM, Nin JWM, Michal M, Folpe AL, Kosemehmetoglu K, Torres-Mora J, Michal M
Mod Pathol 2023 Dec;36(12):100337. Epub 2023 Sep 22 doi: 10.1016/j.modpat.2023.100337. PMID: 37742928
Thway K, Fisher C
Semin Diagn Pathol 2021 Nov;38(6):170-186. Epub 2021 Sep 29 doi: 10.1053/j.semdp.2021.09.005. PMID: 34602314
Feng L, Wang M, Yibulayin F, Zhang H, Yang YL, Ren F, Wushou A
Sci Rep 2018 Mar 22;8(1):5024. doi: 10.1038/s41598-018-23145-4. PMID: 29568070Free PMC Article
Watson S, Perrin V, Guillemot D, Reynaud S, Coindre JM, Karanian M, Guinebretière JM, Freneaux P, Le Loarer F, Bouvet M, Galmiche-Rolland L, Larousserie F, Longchampt E, Ranchere-Vince D, Pierron G, Delattre O, Tirode F
J Pathol 2018 May;245(1):29-40. Epub 2018 Mar 30 doi: 10.1002/path.5053. PMID: 29431183
Broehm C, Al-Ibraheemi A, Fritchie KJ
Pediatr Dev Pathol 2017 Jun;20(3):232-239. Epub 2017 Apr 18 doi: 10.1177/1093526617703540. PMID: 28420320

Diagnosis

Foot O, Hallin M, Jones RL, Sumathi VP, Thway K
Int J Surg Pathol 2021 Apr;29(2):179-181. Epub 2020 Jul 3 doi: 10.1177/1066896920938124. PMID: 32615834
Chapman LW, Yu SS, Arron ST
Semin Cutan Med Surg 2019 Mar 1;38(1):E65-E66. doi: 10.12788/j.sder.2019.008. PMID: 31051027
Thway K
Semin Diagn Pathol 2019 Mar;36(2):112-121. Epub 2019 Feb 28 doi: 10.1053/j.semdp.2019.02.006. PMID: 30852045
Pinto A, Howitt B
Arch Pathol Lab Med 2016 Mar;140(3):286-90. doi: 10.5858/arpa.2014-0523-RS. PMID: 26927725
Fisher C
Adv Anat Pathol 2004 Jul;11(4):190-201. doi: 10.1097/01.pap.0000131773.16130.aa. PMID: 15220822

Therapy

Qi W, Ren Y, Wang H, Wan Y, Wang D, Yao J, Pan H
Sci Rep 2023 Dec 27;13(1):23018. doi: 10.1038/s41598-023-50401-z. PMID: 38155261Free PMC Article
Palmerini E, Jones RL, Marchesi E, Paioli A, Cesari M, Longhi A, Meazza C, Coccoli L, Fagioli F, Asaftei S, Grignani G, Tamburini A, Pollack SM, Picci P, Ferrari S
BMC Cancer 2016 Apr 20;16:280. doi: 10.1186/s12885-016-2312-3. PMID: 27098543Free PMC Article
Ramlawi B, Leja MJ, Abu Saleh WK, Al Jabbari O, Benjamin R, Ravi V, Shapira OM, Blackmon SH, Bruckner BA, Reardon MJ
Ann Thorac Surg 2016 Feb;101(2):698-702. Epub 2015 Oct 21 doi: 10.1016/j.athoracsur.2015.07.087. PMID: 26476808
Abdulai AE, Nuamah IK, Avogo D, Gyasi RK, Renner LA
Ghana Med J 2013 Dec;47(4):208-10. PMID: 24669028Free PMC Article
Sareen P, Chhabra L, Trivedi N
BMJ Case Rep 2013 May 27;2013 doi: 10.1136/bcr-2013-009934. PMID: 23715844Free PMC Article

Prognosis

Schwitzer D, Kim R, Williams F, Hammer D
J Oral Maxillofac Surg 2020 Aug;78(8):1334-1342. Epub 2020 Feb 12 doi: 10.1016/j.joms.2020.02.003. PMID: 32147227
Henry M, Britton C, Coco C, Dadhania VS, Slobodov G
Can J Urol 2019 Feb;26(1):9683-9685. PMID: 30797253
Manmadhan A, Malhotra SP, Weinberg CR, Reyentovich A, Latson LA Jr, Bhatla P, Saric M
J Cardiothorac Surg 2017 Oct 30;12(1):93. doi: 10.1186/s13019-017-0654-9. PMID: 29084562Free PMC Article
Broehm C, Al-Ibraheemi A, Fritchie KJ
Pediatr Dev Pathol 2017 Jun;20(3):232-239. Epub 2017 Apr 18 doi: 10.1177/1093526617703540. PMID: 28420320
Pinto A, Howitt B
Arch Pathol Lab Med 2016 Mar;140(3):286-90. doi: 10.5858/arpa.2014-0523-RS. PMID: 26927725

Clinical prediction guides

Qi W, Ren Y, Wang H, Wan Y, Wang D, Yao J, Pan H
Sci Rep 2023 Dec 27;13(1):23018. doi: 10.1038/s41598-023-50401-z. PMID: 38155261Free PMC Article
Joo MW, Lee YS, Park HS, Chung YG, Yoon C
Curr Oncol 2022 Jun 2;29(6):4068-4080. doi: 10.3390/curroncol29060324. PMID: 35735433Free PMC Article
Watson S, Perrin V, Guillemot D, Reynaud S, Coindre JM, Karanian M, Guinebretière JM, Freneaux P, Le Loarer F, Bouvet M, Galmiche-Rolland L, Larousserie F, Longchampt E, Ranchere-Vince D, Pierron G, Delattre O, Tirode F
J Pathol 2018 May;245(1):29-40. Epub 2018 Mar 30 doi: 10.1002/path.5053. PMID: 29431183
Lee Y, Kim HJ, Yoon H, Choi CM, Oh YM, Lee SD, Lim CM, Kim WS, Koh Y, Lee JS
J Korean Med Sci 2016 Nov;31(11):1755-1760. doi: 10.3346/jkms.2016.31.11.1755. PMID: 27709853Free PMC Article
Pandey M, Mathew A, Abraham EK, Rajan B
J Surg Oncol 2004 Sep 1;87(3):121-5. doi: 10.1002/jso.20110. PMID: 15334638

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