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Thrombocythemia 2, somatic

MedGen UID:
478820
Concept ID:
C3277190
Finding
Synonym: THROMBOCYTHEMIA 2, SOMATIC
 
OMIM®: 159530

Professional guidelines

PubMed

Patnaik MM, Tefferi A
Am J Hematol 2023 Apr;98(4):681-689. Epub 2023 Jan 4 doi: 10.1002/ajh.26828. PMID: 36601682
Stockklausner C, Duffert CM, Cario H, Knöfler R, Streif W, Kulozik AE; THROMKID-Plus Studiengruppe der Gesellschaft für Thrombose- und Hämostaseforschung (GTH) and of Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH)
Ann Hematol 2021 Jul;100(7):1647-1665. Epub 2021 Mar 12 doi: 10.1007/s00277-021-04485-0. PMID: 33712866Free PMC Article
Schafer AI
Blood 2006 Jun 1;107(11):4214-22. Epub 2006 Feb 16 doi: 10.1182/blood-2005-08-3526. PMID: 16484586

Recent clinical studies

Etiology

Patnaik MM, Tefferi A
Am J Hematol 2023 Apr;98(4):681-689. Epub 2023 Jan 4 doi: 10.1002/ajh.26828. PMID: 36601682
Grinfeld J, Nangalia J, Green AR
Haematologica 2017 Jan;102(1):7-17. Epub 2016 Dec 1 doi: 10.3324/haematol.2014.113845. PMID: 27909216Free PMC Article
Bhatt VR
Future Oncol 2014 Dec;10(16):2593-602. doi: 10.2217/fon.14.239. PMID: 25531047
Klampfl T, Gisslinger H, Harutyunyan AS, Nivarthi H, Rumi E, Milosevic JD, Them NC, Berg T, Gisslinger B, Pietra D, Chen D, Vladimer GI, Bagienski K, Milanesi C, Casetti IC, Sant'Antonio E, Ferretti V, Elena C, Schischlik F, Cleary C, Six M, Schalling M, Schönegger A, Bock C, Malcovati L, Pascutto C, Superti-Furga G, Cazzola M, Kralovics R
N Engl J Med 2013 Dec 19;369(25):2379-90. Epub 2013 Dec 10 doi: 10.1056/NEJMoa1311347. PMID: 24325356
Tefferi A
Blood 2011 Mar 31;117(13):3494-504. Epub 2011 Jan 3 doi: 10.1182/blood-2010-11-315614. PMID: 21200024

Diagnosis

Patnaik MM, Tefferi A
Am J Hematol 2023 Apr;98(4):681-689. Epub 2023 Jan 4 doi: 10.1002/ajh.26828. PMID: 36601682
Stockklausner C, Duffert CM, Cario H, Knöfler R, Streif W, Kulozik AE; THROMKID-Plus Studiengruppe der Gesellschaft für Thrombose- und Hämostaseforschung (GTH) and of Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH)
Ann Hematol 2021 Jul;100(7):1647-1665. Epub 2021 Mar 12 doi: 10.1007/s00277-021-04485-0. PMID: 33712866Free PMC Article
Bilbao-Sieyro C, Florido Y, Gómez-Casares MT
Oncotarget 2016 Aug 16;7(33):52614-52617. doi: 10.18632/oncotarget.10376. PMID: 27384487Free PMC Article
Nangalia J, Massie CE, Baxter EJ, Nice FL, Gundem G, Wedge DC, Avezov E, Li J, Kollmann K, Kent DG, Aziz A, Godfrey AL, Hinton J, Martincorena I, Van Loo P, Jones AV, Guglielmelli P, Tarpey P, Harding HP, Fitzpatrick JD, Goudie CT, Ortmann CA, Loughran SJ, Raine K, Jones DR, Butler AP, Teague JW, O'Meara S, McLaren S, Bianchi M, Silber Y, Dimitropoulou D, Bloxham D, Mudie L, Maddison M, Robinson B, Keohane C, Maclean C, Hill K, Orchard K, Tauro S, Du MQ, Greaves M, Bowen D, Huntly BJP, Harrison CN, Cross NCP, Ron D, Vannucchi AM, Papaemmanuil E, Campbell PJ, Green AR
N Engl J Med 2013 Dec 19;369(25):2391-2405. Epub 2013 Dec 10 doi: 10.1056/NEJMoa1312542. PMID: 24325359Free PMC Article
Scott LM, Tong W, Levine RL, Scott MA, Beer PA, Stratton MR, Futreal PA, Erber WN, McMullin MF, Harrison CN, Warren AJ, Gilliland DG, Lodish HF, Green AR
N Engl J Med 2007 Feb 1;356(5):459-68. doi: 10.1056/NEJMoa065202. PMID: 17267906Free PMC Article

Therapy

Agashe RP, Lippman SM, Kurzrock R
Mol Cancer Ther 2022 Dec 2;21(12):1757-1764. doi: 10.1158/1535-7163.MCT-22-0323. PMID: 36252553Free PMC Article
Stockklausner C, Duffert CM, Cario H, Knöfler R, Streif W, Kulozik AE; THROMKID-Plus Studiengruppe der Gesellschaft für Thrombose- und Hämostaseforschung (GTH) and of Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH)
Ann Hematol 2021 Jul;100(7):1647-1665. Epub 2021 Mar 12 doi: 10.1007/s00277-021-04485-0. PMID: 33712866Free PMC Article
Bhatt VR
Future Oncol 2014 Dec;10(16):2593-602. doi: 10.2217/fon.14.239. PMID: 25531047
Levine RL
Curr Top Microbiol Immunol 2012;355:119-33. doi: 10.1007/82_2011_170. PMID: 21823028
Levine RL, Gilliland DG
Blood 2008 Sep 15;112(6):2190-8. doi: 10.1182/blood-2008-03-077966. PMID: 18779404Free PMC Article

Prognosis

Lanikova L, Babosova O, Prchal JT
Genes (Basel) 2019 Oct 15;10(10) doi: 10.3390/genes10100813. PMID: 31618985Free PMC Article
Vainchenker W, Kralovics R
Blood 2017 Feb 9;129(6):667-679. Epub 2016 Dec 27 doi: 10.1182/blood-2016-10-695940. PMID: 28028029
Bilbao-Sieyro C, Florido Y, Gómez-Casares MT
Oncotarget 2016 Aug 16;7(33):52614-52617. doi: 10.18632/oncotarget.10376. PMID: 27384487Free PMC Article
Klampfl T, Gisslinger H, Harutyunyan AS, Nivarthi H, Rumi E, Milosevic JD, Them NC, Berg T, Gisslinger B, Pietra D, Chen D, Vladimer GI, Bagienski K, Milanesi C, Casetti IC, Sant'Antonio E, Ferretti V, Elena C, Schischlik F, Cleary C, Six M, Schalling M, Schönegger A, Bock C, Malcovati L, Pascutto C, Superti-Furga G, Cazzola M, Kralovics R
N Engl J Med 2013 Dec 19;369(25):2379-90. Epub 2013 Dec 10 doi: 10.1056/NEJMoa1311347. PMID: 24325356
Tefferi A
Blood 2011 Mar 31;117(13):3494-504. Epub 2011 Jan 3 doi: 10.1182/blood-2010-11-315614. PMID: 21200024

Clinical prediction guides

Agashe RP, Lippman SM, Kurzrock R
Mol Cancer Ther 2022 Dec 2;21(12):1757-1764. doi: 10.1158/1535-7163.MCT-22-0323. PMID: 36252553Free PMC Article
Levy G, Mambet C, Pecquet C, Bailly S, Havelange V, Diaconu CC, Constantinescu SN
Int Rev Cell Mol Biol 2022;366:41-81. Epub 2021 Sep 23 doi: 10.1016/bs.ircmb.2021.06.004. PMID: 35153006
Nangalia J, Massie CE, Baxter EJ, Nice FL, Gundem G, Wedge DC, Avezov E, Li J, Kollmann K, Kent DG, Aziz A, Godfrey AL, Hinton J, Martincorena I, Van Loo P, Jones AV, Guglielmelli P, Tarpey P, Harding HP, Fitzpatrick JD, Goudie CT, Ortmann CA, Loughran SJ, Raine K, Jones DR, Butler AP, Teague JW, O'Meara S, McLaren S, Bianchi M, Silber Y, Dimitropoulou D, Bloxham D, Mudie L, Maddison M, Robinson B, Keohane C, Maclean C, Hill K, Orchard K, Tauro S, Du MQ, Greaves M, Bowen D, Huntly BJP, Harrison CN, Cross NCP, Ron D, Vannucchi AM, Papaemmanuil E, Campbell PJ, Green AR
N Engl J Med 2013 Dec 19;369(25):2391-2405. Epub 2013 Dec 10 doi: 10.1056/NEJMoa1312542. PMID: 24325359Free PMC Article
Tefferi A
Blood 2011 Mar 31;117(13):3494-504. Epub 2011 Jan 3 doi: 10.1182/blood-2010-11-315614. PMID: 21200024
Levine RL, Gilliland DG
Blood 2008 Sep 15;112(6):2190-8. doi: 10.1182/blood-2008-03-077966. PMID: 18779404Free PMC Article

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