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Diabetes mellitus, noninsulin-dependent, 5(T2D5)

MedGen UID:
863620
•Concept ID:
C4015183
•
Disease or Syndrome
Synonyms: T2D5; TYPE 2 DIABETES 5
 
Gene (location): TBC1D4 (13q22.2)
 
Monarch Initiative: MONDO:0014488
OMIM®: 616087

Definition

Any type 2 diabetes mellitus in which the cause of the disease is a mutation in the TBC1D4 gene. [from MONDO]

Professional guidelines

PubMed

Rural treatment of COVID-19 patients with pirfenidone, nitazoxanide and colchicine. Case series.
Iturbe Esquivel B, Meneses Calderón J, Concepción Carrillo LE, Mendieta Zeron H
Monaldi Arch Chest Dis 2022 Jun 8;93(1) doi: 10.4081/monaldi.2022.2143. PMID: 35678532
Management of type 2 diabetes mellitus in children and adolescents.
Springer SC, Silverstein J, Copeland K, Moore KR, Prazar GE, Raymer T, Shiffman RN, Thaker VV, Anderson M, Spann SJ, Flinn SK; American Academy of Pediatrics
Pediatrics 2013 Feb;131(2):e648-64. Epub 2013 Jan 28 doi: 10.1542/peds.2012-3496. PMID: 23359584
A risk-benefit assessment of metformin in type 2 diabetes mellitus.
Howlett HC, Bailey CJ
Drug Saf 1999 Jun;20(6):489-503. doi: 10.2165/00002018-199920060-00003. PMID: 10392666

Recent clinical studies

Etiology

10-Year Cardiovascular Risk in Patients With Newly Diagnosed Type 2 Diabetes Mellitus.
Gyldenkerne C, Mortensen MB, Kahlert J, Thrane PG, Warnakula Olesen KK, Sørensen HT, Thomsen RW, Maeng M
J Am Coll Cardiol 2023 Oct 17;82(16):1583-1594. doi: 10.1016/j.jacc.2023.08.015. PMID: 37821168
Diabetes mellitus and adverse outcomes after carotid endarterectomy: A systematic review and meta-analysis.
Li F, Zhang R, Di X, Niu S, Rong Z, Liu C, Ni L
Chin Med J (Engl) 2023 Jun 20;136(12):1401-1409. Epub 2023 May 22 doi: 10.1097/CM9.0000000000002730. PMID: 37334731Free PMC Article
Comparing the Efficacies of Telemedicine and Standard Prenatal Care on Blood Glucose Control in Women With Gestational Diabetes Mellitus: Randomized Controlled Trial.
Tian Y, Zhang S, Huang F, Ma L
JMIR Mhealth Uhealth 2021 May 25;9(5):e22881. doi: 10.2196/22881. PMID: 33783365Free PMC Article
Insulin-dependent diabetes and serious trauma.
Liou DZ, Singer MB, Barmparas G, Harada MY, Mirocha J, Bukur M, Salim A, Ley EJ
Eur J Trauma Emerg Surg 2016 Aug;42(4):491-496. Epub 2015 Aug 8 doi: 10.1007/s00068-015-0561-5. PMID: 26253885
Waist circumference as the best predictor of noninsulin dependent diabetes mellitus (NIDDM) compared to body mass index, waist/hip ratio and other anthropometric measurements in Mexican Americans--a 7-year prospective study.
Wei M, Gaskill SP, Haffner SM, Stern MP
Obes Res 1997 Jan;5(1):16-23. doi: 10.1002/j.1550-8528.1997.tb00278.x. PMID: 9061711

Diagnosis

10-Year Cardiovascular Risk in Patients With Newly Diagnosed Type 2 Diabetes Mellitus.
Gyldenkerne C, Mortensen MB, Kahlert J, Thrane PG, Warnakula Olesen KK, Sørensen HT, Thomsen RW, Maeng M
J Am Coll Cardiol 2023 Oct 17;82(16):1583-1594. doi: 10.1016/j.jacc.2023.08.015. PMID: 37821168
Preoperative A1c and Postoperative Infection in Elective Hand Surgery.
Schweitzer TP, Peterson SL
Hand (N Y) 2023 Jul;18(5):785-791. Epub 2022 Jan 29 doi: 10.1177/15589447211065493. PMID: 35094604Free PMC Article
Comparing the Efficacies of Telemedicine and Standard Prenatal Care on Blood Glucose Control in Women With Gestational Diabetes Mellitus: Randomized Controlled Trial.
Tian Y, Zhang S, Huang F, Ma L
JMIR Mhealth Uhealth 2021 May 25;9(5):e22881. doi: 10.2196/22881. PMID: 33783365Free PMC Article
Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha and 4 alpha in maturity-onset diabetes of the young and hyperinsulinemic hypoglycemia.
Colclough K, Bellanne-Chantelot C, Saint-Martin C, Flanagan SE, Ellard S
Hum Mutat 2013 May;34(5):669-85. Epub 2013 Apr 2 doi: 10.1002/humu.22279. PMID: 23348805
Waist circumference as the best predictor of noninsulin dependent diabetes mellitus (NIDDM) compared to body mass index, waist/hip ratio and other anthropometric measurements in Mexican Americans--a 7-year prospective study.
Wei M, Gaskill SP, Haffner SM, Stern MP
Obes Res 1997 Jan;5(1):16-23. doi: 10.1002/j.1550-8528.1997.tb00278.x. PMID: 9061711

Therapy

Diabetes mellitus and adverse outcomes after carotid endarterectomy: A systematic review and meta-analysis.
Li F, Zhang R, Di X, Niu S, Rong Z, Liu C, Ni L
Chin Med J (Engl) 2023 Jun 20;136(12):1401-1409. Epub 2023 May 22 doi: 10.1097/CM9.0000000000002730. PMID: 37334731Free PMC Article
Preoperative A1c and Postoperative Infection in Elective Hand Surgery.
Schweitzer TP, Peterson SL
Hand (N Y) 2023 Jul;18(5):785-791. Epub 2022 Jan 29 doi: 10.1177/15589447211065493. PMID: 35094604Free PMC Article
Comparing the Efficacies of Telemedicine and Standard Prenatal Care on Blood Glucose Control in Women With Gestational Diabetes Mellitus: Randomized Controlled Trial.
Tian Y, Zhang S, Huang F, Ma L
JMIR Mhealth Uhealth 2021 May 25;9(5):e22881. doi: 10.2196/22881. PMID: 33783365Free PMC Article
Insulin-dependent diabetes and serious trauma.
Liou DZ, Singer MB, Barmparas G, Harada MY, Mirocha J, Bukur M, Salim A, Ley EJ
Eur J Trauma Emerg Surg 2016 Aug;42(4):491-496. Epub 2015 Aug 8 doi: 10.1007/s00068-015-0561-5. PMID: 26253885
Glipizide: an overview.
Shuman CR
Am J Med 1983 Nov 30;75(5B):55-9. doi: 10.1016/0002-9343(83)90254-1. PMID: 6369968

Prognosis

Association between pregnancy-related complications and development of type 2 diabetes and hypertension in women: an umbrella review.
Wambua S, Singh M, Okoth K, Snell KIE, Riley RD, Yau C, Thangaratinam S, Nirantharakumar K, Crowe FL; MuM-PreDiCT Group
BMC Med 2024 Feb 14;22(1):66. doi: 10.1186/s12916-024-03284-4. PMID: 38355631Free PMC Article
A single-arm, open-label, intervention study to investigate the improvement of glucose tolerance after administration of the 5-aminolevulinic acid (5-ALA) in the patients with mitochondrial diabetes mellitus.
Nakamura Y, Haraguchi A, Shigeno R, Ito A, Horie I, Kawakami A, Abiru N
Medicine (Baltimore) 2021 Mar 12;100(10):e25100. doi: 10.1097/MD.0000000000025100. PMID: 33725905Free PMC Article
Insulin-dependent diabetes and serious trauma.
Liou DZ, Singer MB, Barmparas G, Harada MY, Mirocha J, Bukur M, Salim A, Ley EJ
Eur J Trauma Emerg Surg 2016 Aug;42(4):491-496. Epub 2015 Aug 8 doi: 10.1007/s00068-015-0561-5. PMID: 26253885
Hypertension and renal complications in type 2 diabetes.
Nosadini R
Semin Vasc Med 2002 Feb;2(1):109-19. doi: 10.1055/s-2002-23101. PMID: 16222601
Waist circumference as the best predictor of noninsulin dependent diabetes mellitus (NIDDM) compared to body mass index, waist/hip ratio and other anthropometric measurements in Mexican Americans--a 7-year prospective study.
Wei M, Gaskill SP, Haffner SM, Stern MP
Obes Res 1997 Jan;5(1):16-23. doi: 10.1002/j.1550-8528.1997.tb00278.x. PMID: 9061711

Clinical prediction guides

Investigating Diabetes Mellitus Patients' Experiences with Self Monitoring Blood Glucose Methods.
Dragamestianou A, Kontoteza IV, Siskou O, Galanis P, Papazafiropoulou A, Konstantakopoulou O, Gallos P, Karagkouni I, Kaitelidou D
Stud Health Technol Inform 2022 Jun 29;295:474-477. doi: 10.3233/SHTI220768. PMID: 35773914
Insulin-dependent diabetes and serious trauma.
Liou DZ, Singer MB, Barmparas G, Harada MY, Mirocha J, Bukur M, Salim A, Ley EJ
Eur J Trauma Emerg Surg 2016 Aug;42(4):491-496. Epub 2015 Aug 8 doi: 10.1007/s00068-015-0561-5. PMID: 26253885
Waist circumference as the best predictor of noninsulin dependent diabetes mellitus (NIDDM) compared to body mass index, waist/hip ratio and other anthropometric measurements in Mexican Americans--a 7-year prospective study.
Wei M, Gaskill SP, Haffner SM, Stern MP
Obes Res 1997 Jan;5(1):16-23. doi: 10.1002/j.1550-8528.1997.tb00278.x. PMID: 9061711
Abdominal obesity as important component of insulin-resistance syndrome.
Després JP
Nutrition 1993 Sep-Oct;9(5):452-9. PMID: 8286886
Glipizide: an overview.
Shuman CR
Am J Med 1983 Nov 30;75(5B):55-9. doi: 10.1016/0002-9343(83)90254-1. PMID: 6369968

Recent systematic reviews

Association between pregnancy-related complications and development of type 2 diabetes and hypertension in women: an umbrella review.
Wambua S, Singh M, Okoth K, Snell KIE, Riley RD, Yau C, Thangaratinam S, Nirantharakumar K, Crowe FL; MuM-PreDiCT Group
BMC Med 2024 Feb 14;22(1):66. doi: 10.1186/s12916-024-03284-4. PMID: 38355631Free PMC Article
Diabetes mellitus and adverse outcomes after carotid endarterectomy: A systematic review and meta-analysis.
Li F, Zhang R, Di X, Niu S, Rong Z, Liu C, Ni L
Chin Med J (Engl) 2023 Jun 20;136(12):1401-1409. Epub 2023 May 22 doi: 10.1097/CM9.0000000000002730. PMID: 37334731Free PMC Article
Sleeve gastrectomy versus Roux-en-Y Gastric Bypass for remission of type 2 diabetes mellitus at 1, 3 and 5 years: a systematic review and meta-analysis.
Fatima K, Farooqui SK, Ajaz I, Ali ST, Hashmi N, Nadeem S, Ghazi SA, Kaleem SH, Bozdar FS, Noorani M
Minerva Gastroenterol (Torino) 2022 Dec;68(4):450-458. Epub 2022 Apr 7 doi: 10.23736/S2724-5985.22.03117-5. PMID: 35388663
Management of type 2 diabetes mellitus in children and adolescents.
Springer SC, Silverstein J, Copeland K, Moore KR, Prazar GE, Raymer T, Shiffman RN, Thaker VV, Anderson M, Spann SJ, Flinn SK; American Academy of Pediatrics
Pediatrics 2013 Feb;131(2):e648-64. Epub 2013 Jan 28 doi: 10.1542/peds.2012-3496. PMID: 23359584
Publication of recruitment methods in focus group research of minority populations with chronic disease: a systematic review.
Ndumele CD, Ableman G, Russell BE, Gurrola E, Hicks LS
J Health Care Poor Underserved 2011 Feb;22(1):5-23. doi: 10.1353/hpu.2011.0031. PMID: 21317503

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