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Obesity, mild, early-onset

MedGen UID:
865330
Concept ID:
C4016893
Finding
Synonym: OBESITY, MILD, EARLY-ONSET
 
OMIM®: 604630

Professional guidelines

PubMed

Dassie F, Lorusso R, Benavides-Varela S, Milan G, Favaretto F, Callus E, Cagnin S, Reggiani F, Minervini G, Tosatto S, Vettor R, Semenza C, Maffei P
Am J Med Genet A 2021 Mar;185(3):732-742. Epub 2021 Jan 7 doi: 10.1002/ajmg.a.62029. PMID: 33410256

Recent clinical studies

Etiology

Aguilar-Salinas CA, Tusie Luna MT
Curr Opin Nephrol Hypertens 2023 Sep 1;32(5):445-450. Epub 2023 Jul 6 doi: 10.1097/MNH.0000000000000914. PMID: 37530085
Peleggi A, Bohonowych J, Strong TV, Schwartz L, Kim SJ
BMC Psychiatry 2021 Sep 6;21(1):438. doi: 10.1186/s12888-021-03436-3. PMID: 34488710Free PMC Article
Twig G, Zucker I, Afek A, Cukierman-Yaffe T, Bendor CD, Derazne E, Lutski M, Shohat T, Mosenzon O, Tzur D, Pinhas-Hamiel O, Tiosano S, Raz I, Gerstein HC, Tirosh A
Diabetes Care 2020 Jul;43(7):1487-1495. Epub 2020 Apr 22 doi: 10.2337/dc19-1988. PMID: 32321731
Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Curran-Everett D, Fitzpatrick AM, Gaston B, Jarjour NN, Sorkness R, Calhoun WJ, Chung KF, Comhair SA, Dweik RA, Israel E, Peters SP, Busse WW, Erzurum SC, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program
Am J Respir Crit Care Med 2010 Feb 15;181(4):315-23. Epub 2009 Nov 5 doi: 10.1164/rccm.200906-0896OC. PMID: 19892860Free PMC Article
Haldar P, Pavord ID, Shaw DE, Berry MA, Thomas M, Brightling CE, Wardlaw AJ, Green RH
Am J Respir Crit Care Med 2008 Aug 1;178(3):218-224. Epub 2008 May 14 doi: 10.1164/rccm.200711-1754OC. PMID: 18480428Free PMC Article

Diagnosis

Shapiro M, Arbel C, Zucker I, Balmor GR, Lutski M, Derazne E, Beer Z, Pinhas-Hamiel O, Mosenzon O, Tzur D, Afek A, Tirosh A, Cukierman-Yaffe T, Gerstein HC, Rosenberg V, Chodick G, Raz I, Twig G
J Clin Endocrinol Metab 2021 Nov 19;106(12):e5043-e5053. doi: 10.1210/clinem/dgab542. PMID: 34291806
Twig G, Zucker I, Afek A, Cukierman-Yaffe T, Bendor CD, Derazne E, Lutski M, Shohat T, Mosenzon O, Tzur D, Pinhas-Hamiel O, Tiosano S, Raz I, Gerstein HC, Tirosh A
Diabetes Care 2020 Jul;43(7):1487-1495. Epub 2020 Apr 22 doi: 10.2337/dc19-1988. PMID: 32321731
van Duinkerken E, Ryan CM
Neurobiol Dis 2020 Feb;134:104608. Epub 2019 Sep 5 doi: 10.1016/j.nbd.2019.104608. PMID: 31494283
Corren J
Discov Med 2013 Apr;15(83):243-9. PMID: 23636141
Hattersley AT
Diabet Med 1998 Jan;15(1):15-24. doi: 10.1002/(SICI)1096-9136(199801)15:1<15::AID-DIA562>3.0.CO;2-M. PMID: 9472859

Therapy

Ito Y, Takeda S, Nakajima T, Oyama A, Takeshita H, Miki K, Takami Y, Takeya Y, Shimamura M, Rakugi H, Morishita R
J Prev Alzheimers Dis 2024;11(1):138-148. doi: 10.14283/jpad.2023.85. PMID: 38230726
Kuhlen JL Jr, Wahlquist AE, Nietert PJ, Bains SN
Am J Med Sci 2014 Dec;348(6):480-5. doi: 10.1097/MAJ.0000000000000346. PMID: 25319436Free PMC Article
Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Curran-Everett D, Fitzpatrick AM, Gaston B, Jarjour NN, Sorkness R, Calhoun WJ, Chung KF, Comhair SA, Dweik RA, Israel E, Peters SP, Busse WW, Erzurum SC, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program
Am J Respir Crit Care Med 2010 Feb 15;181(4):315-23. Epub 2009 Nov 5 doi: 10.1164/rccm.200906-0896OC. PMID: 19892860Free PMC Article
Haldar P, Pavord ID, Shaw DE, Berry MA, Thomas M, Brightling CE, Wardlaw AJ, Green RH
Am J Respir Crit Care Med 2008 Aug 1;178(3):218-224. Epub 2008 May 14 doi: 10.1164/rccm.200711-1754OC. PMID: 18480428Free PMC Article
Carnahan RM, Perry PJ
Drugs Aging 2004;21(6):361-76. doi: 10.2165/00002512-200421060-00002. PMID: 15084139

Prognosis

Shapiro M, Arbel C, Zucker I, Balmor GR, Lutski M, Derazne E, Beer Z, Pinhas-Hamiel O, Mosenzon O, Tzur D, Afek A, Tirosh A, Cukierman-Yaffe T, Gerstein HC, Rosenberg V, Chodick G, Raz I, Twig G
J Clin Endocrinol Metab 2021 Nov 19;106(12):e5043-e5053. doi: 10.1210/clinem/dgab542. PMID: 34291806
Twig G, Zucker I, Afek A, Cukierman-Yaffe T, Bendor CD, Derazne E, Lutski M, Shohat T, Mosenzon O, Tzur D, Pinhas-Hamiel O, Tiosano S, Raz I, Gerstein HC, Tirosh A
Diabetes Care 2020 Jul;43(7):1487-1495. Epub 2020 Apr 22 doi: 10.2337/dc19-1988. PMID: 32321731
Al Tuwaijri A, Alfadhel M
J Pediatr Endocrinol Metab 2019 Apr 24;32(4):409-413. doi: 10.1515/jpem-2018-0505. PMID: 30796847
Auger N, Rhéaume MA, Paradis G, Healy-Profitós J, Hsieh A, Fraser WD
Am J Obstet Gynecol 2017 Apr;216(4):417.e1-417.e8. Epub 2016 Nov 27 doi: 10.1016/j.ajog.2016.11.1043. PMID: 27899314
Hattersley AT
Diabet Med 1998 Jan;15(1):15-24. doi: 10.1002/(SICI)1096-9136(199801)15:1<15::AID-DIA562>3.0.CO;2-M. PMID: 9472859

Clinical prediction guides

Ludar H, Levy-Shraga Y, Admoni O, Majdoub H, Aronovitch KM, Koren I, Rath S, Elias-Assad G, Almashanu S, Mantovani G, Hamiel OP, Tenenbaum-Rakover Y
J Clin Endocrinol Metab 2024 Jan 18;109(2):424-438. doi: 10.1210/clinem/dgad524. PMID: 37669316
Trivedi AP, Hall C, Goss CW, Lew D, Krings JG, McGregor MC, Samant M, Sieren JP, Li H, Schechtman KB, Schirm J, McEleney S, Peterson S, Moore WC, Bleecker ER, Meyers DA, Israel E, Washko GR, Levy BD, Leader JK, Wenzel SE, Fahy JV, Schiebler ML, Fain SB, Jarjour NN, Mauger DT, Reinhardt JM, Newell JD Jr, Hoffman EA, Castro M, Sheshadri A; NHLBI Severe Asthma Research Program (SARP)
Radiology 2022 Aug;304(2):450-459. Epub 2022 Apr 26 doi: 10.1148/radiol.210363. PMID: 35471111Free PMC Article
Marelli C, Lavigne C, Stepien KM, Janssen MCH, Feillet F, Kožich V, Jesina P, Schule R, Kessler C, Redonnet-Vernhet I, Regnier A, Burda P, Baumgartner M, Benoist JF, Huemer M, Mochel F; E-HOD Consortium
J Inherit Metab Dis 2021 May;44(3):777-786. Epub 2020 Nov 2 doi: 10.1002/jimd.12323. PMID: 33089527
Garibaldi BT, Fiksel J, Muschelli J, Robinson ML, Rouhizadeh M, Perin J, Schumock G, Nagy P, Gray JH, Malapati H, Ghobadi-Krueger M, Niessen TM, Kim BS, Hill PM, Ahmed MS, Dobkin ED, Blanding R, Abele J, Woods B, Harkness K, Thiemann DR, Bowring MG, Shah AB, Wang MC, Bandeen-Roche K, Rosen A, Zeger SL, Gupta A
Ann Intern Med 2021 Jan;174(1):33-41. Epub 2020 Sep 22 doi: 10.7326/M20-3905. PMID: 32960645Free PMC Article
Twig G, Zucker I, Afek A, Cukierman-Yaffe T, Bendor CD, Derazne E, Lutski M, Shohat T, Mosenzon O, Tzur D, Pinhas-Hamiel O, Tiosano S, Raz I, Gerstein HC, Tirosh A
Diabetes Care 2020 Jul;43(7):1487-1495. Epub 2020 Apr 22 doi: 10.2337/dc19-1988. PMID: 32321731

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