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Items: 6

1.

Myeloproliferative disorder, chronic, with eosinophilia

PDGFRB-associated chronic eosinophilic leukemia is a type of cancer of blood-forming cells. It is characterized by an elevated number of white blood cells called eosinophils in the blood. These cells help fight infections by certain parasites and are involved in the inflammation associated with allergic reactions. However, these circumstances do not account for the increased number of eosinophils in PDGFRB-associated chronic eosinophilic leukemia. Some people with this condition have an increased number of other types of white blood cells, such as neutrophils or mast cells, in addition to eosinophils. People with this condition can have an enlarged spleen (splenomegaly) or enlarged liver (hepatomegaly). Some affected individuals develop skin rashes, likely as a result of an abnormal immune response due to the increased number of eosinophils. [from MedlinePlus Genetics]

MedGen UID:
377060
Concept ID:
C1851585
Disease or Syndrome
2.

Refractory malignant neoplasm

A malignant neoplasm that does not respond to treatment. [from NCI]

MedGen UID:
146772
Concept ID:
C0677936
Neoplastic Process
3.

Metastatic Prostate Small Cell Carcinoma

Prostate small cell neuroendocrine carcinoma that has spread to another anatomic site. [from NCI]

MedGen UID:
1674106
Concept ID:
C4763838
Neoplastic Process
4.

Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, somatic

MedGen UID:
864469
Concept ID:
C4016032
Finding
5.

Adenocarcinoma of lung, response to tyrosine kinase inhibitor in, somatic

MedGen UID:
342039
Concept ID:
C1851577
Neoplastic Process
6.

Prostate small cell carcinoma

A neuroendocrine carcinoma of the prostate gland with unfavorable prognosis, composed of small cells containing neurosecretory granules. Approximately half of the cases show a mixture of small cells and adenocarcinoma cells. [from MONDO]

MedGen UID:
266251
Concept ID:
C1300585
Neoplastic Process
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