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Metastatic malignant neoplasm in the lymph nodes

MedGen UID:
151947
Concept ID:
C0686619
Neoplastic Process
Synonyms: Lymph Node Metastases; Lymph Node Metastasis; Metastasis, Lymph Node
SNOMED CT: Secondary lymph node cancer (94392001); Secondary malignant neoplasm of lymph node (94392001); Metastatic malignant neoplasm to lymph node (94392001); Cancer metastatic to lymph nodes (94392001); Metastatic malignant neoplasm of lymph node (94392001)
 
Monarch Initiative: MONDO:0005438

Definition

The spread of a malignant neoplasm from its original site of growth to lymph nodes. [from NCI]

Professional guidelines

PubMed

Bischoff LA, Ganly I, Fugazzola L, Buczek E, Faquin WC, Haugen BR, McIver B, McMullen CP, Newbold K, Rocke DJ, Russell MD, Ryder M, Sadow PM, Sherman E, Shindo M, Shonka DC Jr, Singer MC, Stack BC Jr, Wirth LJ, Wong RJ, Randolph GW
JAMA Otolaryngol Head Neck Surg 2024 Mar 1;150(3):265-272. doi: 10.1001/jamaoto.2023.4323. PMID: 38206595
Wuthrick EJ, Harrison LB
Semin Radiat Oncol 2019 Apr;29(2):91-92. doi: 10.1016/j.semradonc.2018.11.009. PMID: 30827457
Li H, Wu X, Cheng X
J Gynecol Oncol 2016 Jul;27(4):e43. doi: 10.3802/jgo.2016.27.e43. PMID: 27171673Free PMC Article

Recent clinical studies

Etiology

Fu N, Fu W, Chen H, Chai W, Qian X, Wang W, Jiang Y, Shen B
Int J Surg 2023 Aug 1;109(8):2196-2203. doi: 10.1097/JS9.0000000000000469. PMID: 37216230Free PMC Article
Fischerova D, Garganese G, Reina H, Fragomeni SM, Cibula D, Nanka O, Rettenbacher T, Testa AC, Epstein E, Guiggi I, Frühauf F, Manegold G, Scambia G, Valentin L
Ultrasound Obstet Gynecol 2021 Jun;57(6):861-879. doi: 10.1002/uog.23617. PMID: 34077608
Betancourt-Cuellar SL, Benveniste MFK, Palacio DP, Hofstetter WL
Radiol Clin North Am 2021 Mar;59(2):219-229. doi: 10.1016/j.rcl.2020.11.008. PMID: 33551083
Wang B, Zhang Y, Qing T, Xing K, Li J, Zhen T, Zhu S, Zhan X
Sci Rep 2021 Jan 13;11(1):1141. doi: 10.1038/s41598-020-80881-2. PMID: 33441952Free PMC Article
Paner GP, Stadler WM, Hansel DE, Montironi R, Lin DW, Amin MB
Eur Urol 2018 Apr;73(4):560-569. Epub 2018 Jan 9 doi: 10.1016/j.eururo.2017.12.018. PMID: 29325693

Diagnosis

Euhus DM
Breast J 2020 Jan;26(1):35-38. Epub 2019 Dec 26 doi: 10.1111/tbj.13719. PMID: 31876073
Wuthrick EJ, Harrison LB
Semin Radiat Oncol 2019 Apr;29(2):91-92. doi: 10.1016/j.semradonc.2018.11.009. PMID: 30827457
Paner GP, Stadler WM, Hansel DE, Montironi R, Lin DW, Amin MB
Eur Urol 2018 Apr;73(4):560-569. Epub 2018 Jan 9 doi: 10.1016/j.eururo.2017.12.018. PMID: 29325693
Karaman S, Detmar M
J Clin Invest 2014 Mar;124(3):922-8. Epub 2014 Mar 3 doi: 10.1172/JCI71606. PMID: 24590277Free PMC Article
Tait CR, Dodwell D, Horgan K
J Pathol 2004 May;203(1):515-8. doi: 10.1002/path.1544. PMID: 15095473

Therapy

Mejia JC, Pasko J
Surg Clin North Am 2020 Jun;100(3):535-549. Epub 2020 Apr 16 doi: 10.1016/j.suc.2020.02.013. PMID: 32402299
Euhus DM
Breast J 2020 Jan;26(1):35-38. Epub 2019 Dec 26 doi: 10.1111/tbj.13719. PMID: 31876073
McGrath TA, Bossuyt PM, Cronin P, Salameh JP, Kraaijpoel N, Schieda N, McInnes MDF
J Magn Reson Imaging 2019 Jun;49(7):e51-e64. Epub 2018 Aug 13 doi: 10.1002/jmri.26198. PMID: 30102435
Engel J, Emeny RT, Hölzel D
Cancer Metastasis Rev 2012 Jun;31(1-2):235-46. doi: 10.1007/s10555-011-9343-7. PMID: 22198520
Kawada K, Taketo MM
Cancer Res 2011 Feb 15;71(4):1214-8. Epub 2011 Jan 6 doi: 10.1158/0008-5472.CAN-10-3277. PMID: 21212413

Prognosis

Teichgraeber DC, Perez F, Guirguis MS, Kapoor MM, Whitman GJ
Ultrasound Q 2021 Jan 13;37(1):43-51. doi: 10.1097/RUQ.0000000000000546. PMID: 33464028
Rao VU, Patil PH, Rajaram BV
J Cancer Res Ther 2016 Jul-Sep;12(3):1114-1116. doi: 10.4103/0973-1482.164705. PMID: 28054520
Das D, Gupta M, Kaur H, Kalucha A
J Oral Sci 2011 Jun;53(2):137-41. doi: 10.2334/josnusd.53.137. PMID: 21712616
Coskun HH, Ferlito A, Medina JE, Robbins KT, Rodrigo JP, Strojan P, Suárez C, Takes RP, Woolgar JA, Shaha AR, de Bree R, Rinaldo A, Silver CE
Head Neck 2011 Oct;33(10):1520-9. Epub 2010 Aug 24 doi: 10.1002/hed.21526. PMID: 20737485
Dominguez-Ventura A, Nichols FC 3rd
Thorac Surg Clin 2006 May;16(2):139-43. doi: 10.1016/j.thorsurg.2005.12.001. PMID: 16805203

Clinical prediction guides

Alameer E, Eagan A, Scholfield DW, Woods RSR, Tuttle RM, Wong RJ, Patel SG, Ganly I
JAMA Otolaryngol Head Neck Surg 2024 Jan 1;150(1):49-56. doi: 10.1001/jamaoto.2023.3668. PMID: 37971746Free PMC Article
Kim DH, Kim SW, Hwang SH
Laryngoscope 2021 Sep;131(9):1990-1996. Epub 2021 Jan 25 doi: 10.1002/lary.29426. PMID: 33493364
Edge SB, Compton CC
Ann Surg Oncol 2010 Jun;17(6):1471-4. doi: 10.1245/s10434-010-0985-4. PMID: 20180029
Oonk MH, Hollema H, de Hullu JA, van der Zee AG
Int J Gynecol Cancer 2006 May-Jun;16(3):963-71. doi: 10.1111/j.1525-1438.2006.00387.x. PMID: 16803470
Kowalski LP, Medina JE
Otolaryngol Clin North Am 1998 Aug;31(4):621-37. doi: 10.1016/s0030-6665(05)70076-1. PMID: 9687325

Recent systematic reviews

Gao X, Yang Y, Wang Y, Huang Y
Int J Hyperthermia 2023 Dec;40(1):2244713. doi: 10.1080/02656736.2023.2244713. PMID: 37604507
Wei X, Wang X, Xiong J, Li C, Liao Y, Zhu Y, Mao J
Biomed Res Int 2022;2022:9959649. Epub 2022 May 18 doi: 10.1155/2022/9959649. PMID: 35647194Free PMC Article
Akazawa M, Hashimoto K
Artif Intell Med 2021 Oct;120:102164. Epub 2021 Sep 3 doi: 10.1016/j.artmed.2021.102164. PMID: 34629152
Mao J, Zhang Q, Zhang H, Zheng K, Wang R, Wang G
Front Endocrinol (Lausanne) 2020;11:265. Epub 2020 May 15 doi: 10.3389/fendo.2020.00265. PMID: 32477264Free PMC Article
Chang JM, Leung JWT, Moy L, Ha SM, Moon WK
Radiology 2020 Jun;295(3):500-515. Epub 2020 Apr 21 doi: 10.1148/radiol.2020192534. PMID: 32315268

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