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Actinomycotic infection

MedGen UID:: 1733
•Concept ID:: C0001261
•: Disease or Syndrome

Synonyms:	Actinomyces israeli; Actinomycetes; Actinomycosis; Anaerobic actinomyces infection; Canaliculitis; Keratoactinomycosis
SNOMED CT:	Actinomycotic infection (11817007); Actinomycosis (11817007)
Modes of inheritance:	Not genetically inherited MedGen UID: 988794 •Concept ID: CN307044 • Finding Source: Orphanet clinical entity without genetic inheritance. See: This record Not genetically inherited (Orphanet)

Monarch Initiative:	MONDO:0005631
Orphanet:	ORPHA457095

Definition

A rare bacterial infectious disease characterized by a chronic granulomatous infection by <i>Actinomyces</i> species which are commensals in the human gastrointestinal and urogenital tract and oropharynx. Corresponding to the affected site, the disease presents as cervicofacial, respiratory tract, genitourinary tract, digestive tract, central nervous system, or cutaneous actinomycosis and leads to the formation of abscesses and fistulae in the respective region. [from ORDO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVActinomycotic infection

Clinical finding
- Finding by Cause
  - Infection
    - Bacterial Infections and Mycoses
      - Bacterial infectious disease
        Actinomycetales infectious disease
        Actinomycotic infection
        Actinomycotic mycetoma
        Cervicofacial actinomycosis
        Whipple disease

Professional guidelines

PubMed

A modified two-step treatment for actinomycetoma.

Ramam M, Bhat R, Garg T, Sharma VK, Ray R, Singh MK, Banerjee U, Rajendran C
Indian J Dermatol Venereol Leprol 2007 Jul-Aug;73(4):235-9. doi: 10.4103/0378-6323.32888. PMID: 17675730

Differential diagnosis of rib lesions: a case study from Middle Woodland southern Ontario circa 230 A.D.

Molto JE
Am J Phys Anthropol 1990 Dec;83(4):439-47. doi: 10.1002/ajpa.1330830405. PMID: 2275481

Pelvic actinomycosis associated with the use of intrauterine devices. Diagnostic and therapeutic criteria.

Surico N, Tavassoli K, Porcelli A, Wierdis T
Panminerva Med 1987 Jan-Mar;29(1):57-60. PMID: 3601420

See all (3)

Recent clinical studies

Etiology

Pelvic actinomycosis associated with the use of intrauterine devices. Diagnostic and therapeutic criteria.

Surico N, Tavassoli K, Porcelli A, Wierdis T
Panminerva Med 1987 Jan-Mar;29(1):57-60. PMID: 3601420

See all (1)

Diagnosis

Actinomycotic Sinomaxillary Infection in a COVID-19 Patient: A Case Report and Review of the Literature.

Moaddabi A, Cernera M, Armogida NG, Soltani P, Spagnuolo G
J Investig Med High Impact Case Rep 2023 Jan-Dec;11:23247096231217823. doi: 10.1177/23247096231217823. PMID: 38102073 Free PMC Article

Actinomycotic Abscess of Thyroid Gland in a 3-Year-Old Child.

Pitekova B, Kralik R, Kunzo S, Bojnansky J, Podracka L
J Investig Med High Impact Case Rep 2021 Jan-Dec;9:23247096211051923. doi: 10.1177/23247096211051923. PMID: 34727751 Free PMC Article

Periapical actinomycosis: a review.

Jeansonne BG
Quintessence Int 2005 Feb;36(2):149-53. PMID: 15732551

Actinomycotic canaliculitis.

Smith RL, Henderson PN
Aust J Ophthalmol 1980 Feb;8(1):75-9. doi: 10.1111/j.1442-9071.1980.tb00895.x. PMID: 7387549

Primary hepatic actinomycosis.

Meade RH 3rd
Gastroenterology 1980 Feb;78(2):355-9. PMID: 7350060

See all (38)

Therapy

Isolated Actinomycosis of the Hard Palate Incurred Subsequent to Local Anesthesia.

Gurbanov V, Torul D
J Craniofac Surg 2019 Oct;30(7):e645-e646. doi: 10.1097/SCS.0000000000005701. PMID: 31233004

Update on new medicinal applications of gentamicin: evidence-based review.

Chen C, Chen Y, Wu P, Chen B
J Formos Med Assoc 2014 Feb;113(2):72-82. Epub 2013 Nov 9 doi: 10.1016/j.jfma.2013.10.002. PMID: 24216440

Actinomycotic infection of the abdominal wall mimicking a malignant neoplasm.

Yi F, Prasad S, Sharkey F, Kahlenberg M
Surg Infect (Larchmt) 2008 Feb;9(1):85-9. doi: 10.1089/sur.2006.055. PMID: 18363472

Actinomycotic abscess of the thyroid gland in an infant.

Oysu C, Uslu C, Guclu O, Oysu A
Int J Pediatr Otorhinolaryngol 2005 May;69(5):701-3. Epub 2005 Jan 26 doi: 10.1016/j.ijporl.2004.12.003. PMID: 15850692

Primary hepatic actinomycosis.

Meade RH 3rd
Gastroenterology 1980 Feb;78(2):355-9. PMID: 7350060

See all (27)

Prognosis

Primary laryngeal actinomycosis in an immunosuppressed woman: a case report.

Abed T, Ahmed J, O'Shea N, Payne S, Watters GW
Ear Nose Throat J 2013 Jul;92(7):301-3. doi: 10.1177/014556131309200708. PMID: 23904305

Osteomyelitis of the hard palate secondary to actinomycosis: a case report.

Garg R, Schalch P, Pepper JP, Nguyen QA
Ear Nose Throat J 2011 Mar;90(3):E11-2. doi: 10.1177/014556131109000316. PMID: 21412725

Thoracic actinomycosis.

Hsieh MJ, Liu HP, Chang JP, Chang CH
Chest 1993 Aug;104(2):366-70. doi: 10.1378/chest.104.2.366. PMID: 8339619

Pericarditis, pneumonia and brain abscess due to a combined Actinomyces--Actinobacillus actinomycetemcomitans infection.

Zijlstra EE, Swart GR, Godfroy FJ, Degener JE
J Infect 1992 Jul;25(1):83-7. doi: 10.1016/0163-4453(92)93633-2. PMID: 1522328

Pelvic actinomycosis.

Cohen A, Silberberg B
Int J Gynaecol Obstet 1976;14(3):239-45. PMID: 13011

See all (7)

Clinical prediction guides

Acute actinomycotic brain abscess in a patient with rheumatoid arthritis.

Shintaku M, Kono F, Ando K, Kobayashi Y, Hasegawa H, Tsutsumi Y
Neuropathology 2020 Dec;40(6):641-645. Epub 2020 Nov 18 doi: 10.1111/neup.12699. PMID: 33210383

Tonsillolithiasis with actinomycotic infection: a case report.

Tatar EC, Karaçay M, Saylam G, Korkmaz H, Ozdek A
Kulak Burun Bogaz Ihtis Derg 2009 Jul-Aug;19(4):203-6. PMID: 19860635

Rare lesions of the oral cavity: case report of an actinomycotic lesion limited to the gingiva.

Sakallioğlu U, Açikgöz G, Kirtiloğlu T, Karagöz F
J Oral Sci 2003 Mar;45(1):39-42. PMID: 12816363

Actinomycosis, a sheep in wolves' clothes.

Neijens V, van Heerde P, van der Heijden A, Baas P
Lung Cancer 1996 Aug;15(1):131-5. doi: 10.1016/0169-5002(96)00578-8. PMID: 8865131

Serum antibodies to pathogenic actinomycetes in the normal human population.

Weil HP, Schaal KP
Zentralbl Bakteriol 1990 Dec;274(3):398-405. doi: 10.1016/s0934-8840(11)80698-5. PMID: 2090155

See all (5)