U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from PMC

Allergic asthma

MedGen UID:
102343
•Concept ID:
C0155877
•
Disease or Syndrome
Synonym: Asthma, atopic
SNOMED CT: Allergic asthma (389145006)
 
Monarch Initiative: MONDO:0004784

Definition

A asthma with a basis in a pathological type I hypersensitivity reaction. [from MONDO]

Professional guidelines

PubMed

Characteristics, phenotypes, mechanisms and management of severe asthma.
Chung KF, Dixey P, Abubakar-Waziri H, Bhavsar P, Patel PH, Guo S, Ji Y
Chin Med J (Engl) 2022 May 20;135(10):1141-1155. doi: 10.1097/CM9.0000000000001990. PMID: 35633594Free PMC Article
A Current Perspective of Allergic Asthma: From Mechanisms to Management.
Papadopoulos NG, Miligkos M, Xepapadaki P
Handb Exp Pharmacol 2022;268:69-93. doi: 10.1007/164_2021_483. PMID: 34085124
Asthma in adults: Principles of treatment.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):396-402. doi: 10.2500/aap.2019.40.4256. PMID: 31690379

Curated

UK NICE Guideline NG80, Asthma: diagnosis, monitoring and chronic asthma management, 2021

Recent clinical studies

Etiology

The causality between intestinal flora and allergic diseases: Insights from a bi-directional two-sample Mendelian randomization analysis.
Jin Q, Ren F, Dai D, Sun N, Qian Y, Song P
Front Immunol 2023;14:1121273. Epub 2023 Mar 9 doi: 10.3389/fimmu.2023.1121273. PMID: 36969260Free PMC Article
Allergic Endotypes and Phenotypes of Asthma.
Akar-Ghibril N, Casale T, Custovic A, Phipatanakul W
J Allergy Clin Immunol Pract 2020 Feb;8(2):429-440. doi: 10.1016/j.jaip.2019.11.008. PMID: 32037107Free PMC Article
Asthma in adults: Principles of treatment.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):396-402. doi: 10.2500/aap.2019.40.4256. PMID: 31690379
Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis.
Dhami S, Kakourou A, Asamoah F, Agache I, Lau S, Jutel M, Muraro A, Roberts G, Akdis CA, Bonini M, Cavkaytar O, Flood B, Gajdanowicz P, Izuhara K, Kalayci Ö, Mosges R, Palomares O, Pfaar O, Smolinska S, Sokolowska M, Asaria M, Netuveli G, Zaman H, Akhlaq A, Sheikh A
Allergy 2017 Dec;72(12):1825-1848. Epub 2017 Jul 6 doi: 10.1111/all.13208. PMID: 28543086
The allergic asthma phenotype.
Schatz M, Rosenwasser L
J Allergy Clin Immunol Pract 2014 Nov-Dec;2(6):645-8; quiz 649. Epub 2014 Nov 6 doi: 10.1016/j.jaip.2014.09.004. PMID: 25439351

Diagnosis

A Current Perspective of Allergic Asthma: From Mechanisms to Management.
Papadopoulos NG, Miligkos M, Xepapadaki P
Handb Exp Pharmacol 2022;268:69-93. doi: 10.1007/164_2021_483. PMID: 34085124
Allergic Endotypes and Phenotypes of Asthma.
Akar-Ghibril N, Casale T, Custovic A, Phipatanakul W
J Allergy Clin Immunol Pract 2020 Feb;8(2):429-440. doi: 10.1016/j.jaip.2019.11.008. PMID: 32037107Free PMC Article
Asthma in adults: Principles of treatment.
Kwah JH, Peters AT
Allergy Asthma Proc 2019 Nov 1;40(6):396-402. doi: 10.2500/aap.2019.40.4256. PMID: 31690379
Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis.
Dhami S, Kakourou A, Asamoah F, Agache I, Lau S, Jutel M, Muraro A, Roberts G, Akdis CA, Bonini M, Cavkaytar O, Flood B, Gajdanowicz P, Izuhara K, Kalayci Ö, Mosges R, Palomares O, Pfaar O, Smolinska S, Sokolowska M, Asaria M, Netuveli G, Zaman H, Akhlaq A, Sheikh A
Allergy 2017 Dec;72(12):1825-1848. Epub 2017 Jul 6 doi: 10.1111/all.13208. PMID: 28543086
The allergic asthma phenotype.
Schatz M, Rosenwasser L
J Allergy Clin Immunol Pract 2014 Nov-Dec;2(6):645-8; quiz 649. Epub 2014 Nov 6 doi: 10.1016/j.jaip.2014.09.004. PMID: 25439351

Therapy

Tezepelumab in patients with allergic and eosinophilic asthma.
Caminati M, Buhl R, Corren J, Hanania NA, Kim H, Korn S, Lommatzsch M, Martin N, Matucci A, Nasser SM, Pavord ID, Domingo C
Allergy 2024 May;79(5):1134-1145. Epub 2023 Dec 26 doi: 10.1111/all.15986. PMID: 38146651
Dupilumab Efficacy in Patients with Uncontrolled, Moderate-to-Severe Allergic Asthma.
Corren J, Castro M, O'Riordan T, Hanania NA, Pavord ID, Quirce S, Chipps BE, Wenzel SE, Thangavelu K, Rice MS, Harel S, Jagerschmidt A, Khan AH, Kamat S, Maroni J, Rowe P, Lu Y, Amin N, Pirozzi G, Ruddy M, Graham NMH, Teper A
J Allergy Clin Immunol Pract 2020 Feb;8(2):516-526. Epub 2019 Sep 12 doi: 10.1016/j.jaip.2019.08.050. PMID: 31521831
Immunotherapy for pet allergies.
Virtanen T
Hum Vaccin Immunother 2018 Apr 3;14(4):807-814. Epub 2017 Dec 21 doi: 10.1080/21645515.2017.1409315. PMID: 29182437Free PMC Article
Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis.
Dhami S, Kakourou A, Asamoah F, Agache I, Lau S, Jutel M, Muraro A, Roberts G, Akdis CA, Bonini M, Cavkaytar O, Flood B, Gajdanowicz P, Izuhara K, Kalayci Ö, Mosges R, Palomares O, Pfaar O, Smolinska S, Sokolowska M, Asaria M, Netuveli G, Zaman H, Akhlaq A, Sheikh A
Allergy 2017 Dec;72(12):1825-1848. Epub 2017 Jul 6 doi: 10.1111/all.13208. PMID: 28543086
Omalizumab in severe allergic asthma inadequately controlled with standard therapy: a randomized trial.
Hanania NA, Alpan O, Hamilos DL, Condemi JJ, Reyes-Rivera I, Zhu J, Rosen KE, Eisner MD, Wong DA, Busse W
Ann Intern Med 2011 May 3;154(9):573-82. doi: 10.7326/0003-4819-154-9-201105030-00002. PMID: 21536936

Prognosis

Research Progress in Atopic March.
Yang L, Fu J, Zhou Y
Front Immunol 2020;11:1907. Epub 2020 Aug 27 doi: 10.3389/fimmu.2020.01907. PMID: 32973790Free PMC Article
Allergen Immunotherapy for Local Respiratory Allergy.
Eguiluz-Gracia I, Ariza A, Testera-Montes A, Rondón C, Campo P
Curr Allergy Asthma Rep 2020 May 19;20(7):23. doi: 10.1007/s11882-020-00920-w. PMID: 32430550
Asthma phenotypes: nonallergic (intrinsic) asthma.
Peters SP
J Allergy Clin Immunol Pract 2014 Nov-Dec;2(6):650-2. Epub 2014 Oct 3 doi: 10.1016/j.jaip.2014.09.006. PMID: 25439352
The allergic asthma phenotype.
Schatz M, Rosenwasser L
J Allergy Clin Immunol Pract 2014 Nov-Dec;2(6):645-8; quiz 649. Epub 2014 Nov 6 doi: 10.1016/j.jaip.2014.09.004. PMID: 25439351
Omalizumab in severe allergic asthma inadequately controlled with standard therapy: a randomized trial.
Hanania NA, Alpan O, Hamilos DL, Condemi JJ, Reyes-Rivera I, Zhu J, Rosen KE, Eisner MD, Wong DA, Busse W
Ann Intern Med 2011 May 3;154(9):573-82. doi: 10.7326/0003-4819-154-9-201105030-00002. PMID: 21536936

Clinical prediction guides

Real-World Effectiveness of Omalizumab in Severe Allergic Asthma: A Meta-Analysis of Observational Studies.
Bousquet J, Humbert M, Gibson PG, Kostikas K, Jaumont X, Pfister P, Nissen F
J Allergy Clin Immunol Pract 2021 Jul;9(7):2702-2714. Epub 2021 Jan 21 doi: 10.1016/j.jaip.2021.01.011. PMID: 33486142
Dupilumab Efficacy in Patients with Uncontrolled, Moderate-to-Severe Allergic Asthma.
Corren J, Castro M, O'Riordan T, Hanania NA, Pavord ID, Quirce S, Chipps BE, Wenzel SE, Thangavelu K, Rice MS, Harel S, Jagerschmidt A, Khan AH, Kamat S, Maroni J, Rowe P, Lu Y, Amin N, Pirozzi G, Ruddy M, Graham NMH, Teper A
J Allergy Clin Immunol Pract 2020 Feb;8(2):516-526. Epub 2019 Sep 12 doi: 10.1016/j.jaip.2019.08.050. PMID: 31521831
Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis.
Dhami S, Kakourou A, Asamoah F, Agache I, Lau S, Jutel M, Muraro A, Roberts G, Akdis CA, Bonini M, Cavkaytar O, Flood B, Gajdanowicz P, Izuhara K, Kalayci Ö, Mosges R, Palomares O, Pfaar O, Smolinska S, Sokolowska M, Asaria M, Netuveli G, Zaman H, Akhlaq A, Sheikh A
Allergy 2017 Dec;72(12):1825-1848. Epub 2017 Jul 6 doi: 10.1111/all.13208. PMID: 28543086
The allergic asthma phenotype.
Schatz M, Rosenwasser L
J Allergy Clin Immunol Pract 2014 Nov-Dec;2(6):645-8; quiz 649. Epub 2014 Nov 6 doi: 10.1016/j.jaip.2014.09.004. PMID: 25439351
Omalizumab in severe allergic asthma inadequately controlled with standard therapy: a randomized trial.
Hanania NA, Alpan O, Hamilos DL, Condemi JJ, Reyes-Rivera I, Zhu J, Rosen KE, Eisner MD, Wong DA, Busse W
Ann Intern Med 2011 May 3;154(9):573-82. doi: 10.7326/0003-4819-154-9-201105030-00002. PMID: 21536936

Recent systematic reviews

Tezepelumab compared with other biologics for the treatment of severe asthma: a systematic review and indirect treatment comparison.
Menzies-Gow A, Steenkamp J, Singh S, Erhardt W, Rowell J, Rane P, Martin N, Ackert JL, Quinton A
J Med Econ 2022 Jan-Dec;25(1):679-690. doi: 10.1080/13696998.2022.2074195. PMID: 35570578
Efficacy and safety of treatment with biologicals (benralizumab, dupilumab and omalizumab) for severe allergic asthma: A systematic review for the EAACI Guidelines - recommendations on the use of biologicals in severe asthma.
Agache I, Rocha C, Beltran J, Song Y, Posso M, Solà I, Alonso-Coello P, Akdis C, Akdis M, Canonica GW, Casale T, Chivato T, Corren J, Del Giacco S, Eiwegger T, Firinu D, Gern JE, Hamelmann E, Hanania N, Mäkelä M, Martín IH, Nair P, O'Mahony L, Papadopoulos NG, Papi A, Park HS, Pérez de Llano L, Quirce S, Sastre J, Shamji M, Schwarze J, Canelo-Aybar C, Palomares O, Jutel M
Allergy 2020 May;75(5):1043-1057. doi: 10.1111/all.14235. PMID: 32064642
Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis.
Dhami S, Kakourou A, Asamoah F, Agache I, Lau S, Jutel M, Muraro A, Roberts G, Akdis CA, Bonini M, Cavkaytar O, Flood B, Gajdanowicz P, Izuhara K, Kalayci Ö, Mosges R, Palomares O, Pfaar O, Smolinska S, Sokolowska M, Asaria M, Netuveli G, Zaman H, Akhlaq A, Sheikh A
Allergy 2017 Dec;72(12):1825-1848. Epub 2017 Jul 6 doi: 10.1111/all.13208. PMID: 28543086
A systematic review of the association between allergic asthma and autism.
Tonacci A, Billeci L, Ruta L, Tartarisco G, Pioggia G, Gangemi S
Minerva Pediatr 2017 Dec;69(6):538-550. Epub 2016 Oct 5 doi: 10.23736/S0026-4946.16.04623-5. PMID: 27706122
Indoor fungal diversity and asthma: a meta-analysis and systematic review of risk factors.
Sharpe RA, Bearman N, Thornton CR, Husk K, Osborne NJ
J Allergy Clin Immunol 2015 Jan;135(1):110-22. Epub 2014 Aug 23 doi: 10.1016/j.jaci.2014.07.002. PMID: 25159468

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2021
      UK NICE Guideline NG80, Asthma: diagnosis, monitoring and chronic asthma management, 2021

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...