Sterile Alpha Motif

A putative protein interaction module, approximately 70 amino acids long, that forms a small five-helix bundle with two large interfaces which may homo- and hetero-oligomerize, or bind non-sterile-alpha motif targets. The sterile alpha motif is present in a wide variety of eukaryotic proteins that function in diverse biological processes.

Year introduced: 2017

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Tree Number(s): G02.111.570.820.709.275.500.898, G02.111.570.820.709.275.750.500.813

MeSH Unique ID: D000071682

Entry Terms:

• Motifs, Sterile Alpha
• Motif, Sterile Alpha
• Sterile Alpha Motifs
• SAM Domain
• SAM Domains
• Sterile Alpha Motif Domain

Previous Indexing:

• Protein Structure, Tertiary (1998-2016)

All MeSH Categories
Phenomena and Processes Category
Chemical Phenomena
Biochemical Phenomena
Molecular Structure
Molecular Conformation
Protein Conformation
Protein Structural Elements
Amino Acid Motifs
Sterile Alpha Motif

All MeSH Categories
Phenomena and Processes Category
Chemical Phenomena
Biochemical Phenomena
Molecular Structure
Molecular Conformation
Protein Conformation
Protein Structural Elements
Protein Domains
Protein Interaction Domains and Motifs
Sterile Alpha Motif