Transcription Factor HES-1
A basic-helix-loop-helix transcription factor that functions as a transcriptional repressor for genes transcribed by bHLH proteins. For example, it may negatively regulate MYOGENESIS by inhibiting MyoD1 and ASH1 proteins. It is also required for the stability of FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS and their localization to the cell nucleus in response to DNA DAMAGE.
Year introduced: 2017
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Subheadings:
Tree Number(s): D12.776.260.103.844, D12.776.930.125.844
MeSH Unique ID: D000072056
Entry Terms:
- HES-1, Transcription Factor
- Transcription Factor HES 1
- Hairy and Enhancer of Split 1 Protein
- Hairy-Like Transcription Factor
- Hairy Like Transcription Factor
- Transcription Factor, Hairy-Like
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