ATP Binding Cassette Transporter, Subfamily D
A sub-family of ATP-binding cassette transporters that localize to the membranes of PEROXISOMES; ENDOPLASMIC RETICULUM; and LYSOSOMES. Members contain a transmembrane domain in their N-terminal half and generally function as homodimers in the transport of LIPIDS; BILE ACIDS; and VITAMIN B12. Mutations in some ABCD transporter genes are associated with PEROXISOMAL DISORDERS.
Year introduced: 2019 (2018)
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Subheadings:
Tree Number(s): D09.400.430.890.020.419, D12.776.157.530.100.209, D12.776.395.550.020.419, D12.776.543.550.192.419, D12.776.543.585.100.209
MeSH Unique ID: D000074061
Entry Terms:
- ATP Binding Cassette Transporter, Sub-Family D
- ATP Binding Cassette Transporter, Sub Family D
- ABC Transporter Subfamily D
- ABCD Transporters
- Transporters, ABCD
- ABCD Proteins
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