Solute Carrier Organic Anion Transporter Family Member 1B3
A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.
Year introduced: 2018
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Subheadings:
Tree Number(s): D12.776.157.530.450.074.500.781.875, D12.776.157.530.937.905, D12.776.543.585.450.074.500.875.875, D12.776.543.585.937.950
MeSH Unique ID: D000074542
Entry Terms:
- OATP8 Protein
- SLC21A8 Protein
- Liver-Specific Organic Anion Transporter-2
- Liver Specific Organic Anion Transporter 2
- OATP1B3 Protein
- Solute Carrier Family 21 Member 8 Protein
- SLCO1B3 Protein
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