Medium Spiny Neurons

Medium sized, inhibitory GABAergic neurons in the CORPUS STRIATUM with highly developed dendritic trees. They are divided into neurons expressing DOPAMINE D1 RECEPTORS which project preferentially to the SUBSTANTIA NIGRA PARS RETICULATA and neurons expressing DOPAMINE D2 RECEPTORS which project preferentially to the lateral part of the GLOBUS PALLIDUS. Medium spiny neurons are preferentially lost in HUNTINGTON DISEASE.

Year introduced: 2023

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Tree Number(s): A08.675.289.500, A08.675.650.535, A11.671.285.500, A11.671.650.535

MeSH Unique ID: D000094242

Entry Terms:

• Medium Spiny Neuron
• Neuron, Medium Spiny
• Striatal Medium-Sized Spiny Neurons
• Striatal Medium Sized Spiny Neurons

Previous Indexing:

• Corpus Striatum (1983-2022)
• Neurons (1983-2022)

See Also:

• Corpus Striatum

All MeSH Categories
Anatomy Category
Nervous System
Neurons
GABAergic Neurons
Medium Spiny Neurons

All MeSH Categories
Anatomy Category
Nervous System
Neurons
Neurons, Afferent
Medium Spiny Neurons

All MeSH Categories
Anatomy Category
Cells
Neurons
GABAergic Neurons
Medium Spiny Neurons

All MeSH Categories
Anatomy Category
Cells
Neurons
Neurons, Afferent
Medium Spiny Neurons