RNA Caps

Nucleic acid structures found on the 5' end of eukaryotic cellular and viral messenger RNA and some heterogeneous nuclear RNAs. These structures, which are positively charged, protect the above specified RNAs at their termini against attack by phosphatases and other nucleases and promote mRNA function at the level of initiation of translation. Analogs of the RNA caps (RNA CAP ANALOGS), which lack the positive charge, inhibit the initiation of protein synthesis.

Year introduced: 1980

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Tree Number(s): D03.633.100.759.646.454.700, D13.444.735.544.500, D13.695.667.454.700, D13.695.827.426.700

MeSH Unique ID: D012315

Entry Terms:

• Caps, RNA
• RNA Cap
• Cap, RNA
• 5' mRNA Cap Structure
• 5' Capped RNA
• RNA, 5' Capped

Previous Indexing:

• Guanine Nucleotides (1966-1971)
• Guanosine Triphosphate (1972-1974)/analogs and derivatives (1975-1979)
• Oligoribonucleotides (1976-1979)
• Ribonucleotides (1971-1975)
• RNA, Messenger (1966-1979)

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, Fused-Ring
Heterocyclic Compounds, 2-Ring
Purines
Purine Nucleotides
Guanine Nucleotides
RNA Caps
RNA Cap Analogs

All MeSH Categories
Chemicals and Drugs Category
Nucleic Acids, Nucleotides, and Nucleosides
Nucleic Acids
RNA
RNA, Messenger
RNA Caps
RNA Cap Analogs

All MeSH Categories
Chemicals and Drugs Category
Nucleic Acids, Nucleotides, and Nucleosides
Nucleotides
Purine Nucleotides
Guanine Nucleotides
RNA Caps
RNA Cap Analogs

All MeSH Categories
Chemicals and Drugs Category
Nucleic Acids, Nucleotides, and Nucleosides
Nucleotides
Ribonucleotides
Guanine Nucleotides
RNA Caps
RNA Cap Analogs