Gene Products, nef
Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate of viral infectivity and the destruction of the host immune system. nef gene products were originally found as factors that trans-suppress viral replication and function as negative regulators of transcription. nef stands for negative factor.
Year introduced: 1991(1990)
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Subheadings:
Tree Number(s): D12.776.964.775.362, D12.776.964.925.500
MeSH Unique ID: D015693
Entry Terms:
- 3'-orf Protein
- 3' orf Protein
- Gene Product, nef
- nef Gene Product
- nef Gene Products
- nef Protein
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