Antigenic Modulation

Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumors escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies.

Year introduced: 1992

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Tree Number(s): G12.122.140

MeSH Unique ID: D016525

Entry Terms:

• Antigenic Modulations
• Modulation, Antigenic
• Modulations, Antigenic

Previous Indexing:

• Antigen-Antibody Reactions (1968-1989)
• Antigens, Surface/analysis (1979-1991)
• Antigens, Surface/immunology (1979-1988)

All MeSH Categories
Phenomena and Processes Category
Immune System Phenomena
Antigen-Antibody Reactions
Antigenic Modulation