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Porphyria, Erythropoietic

An autosomal recessive porphyria that is due to a deficiency of UROPORPHYRINOGEN III SYNTHASE in the BONE MARROW; also known as congenital erythropoietic porphyria. This disease is characterized by SPLENOMEGALY; ANEMIA; photosensitivity; cutaneous lesions; accumulation of hydroxymethylbilane; and increased excretion of UROPORPHYRINS and COPROPORPHYRINS.

Year introduced: 1993

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Tree Number(s): C16.320.850.738, C17.800.827.738, C18.452.811.250

MeSH Unique ID: D017092

Entry Terms:

  • Erythropoietic Porphyrias
  • Porphyrias, Erythropoietic
  • Congenital Erythropoietic Porphyria
  • Congenital Erythropoietic Porphyrias
  • Erythropoietic Porphyria, Congenital
  • Erythropoietic Porphyrias, Congenital
  • Porphyrias, Congenital Erythropoietic
  • Erythropoietic Porphyria
  • Gunther Disease
  • Gunther's Disease
  • Gunthers Disease
  • Porphyria, Congenital Erythropoietic
  • Porphyria, Erythropoietic, Congenital
  • Deficiency of Uroporphyrinogen III Synthase
  • Uroporphyrinogen III Synthase, Deficiency of
  • UROS Deficiency

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