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Proglucagon

The common precursor polypeptide of pancreatic GLUCAGON and intestinal GLUCAGON-LIKE PEPTIDES. Proglucagon is the 158-amino acid segment of preproglucagon without the N-terminal signal sequence. Proglucagon is expressed in the PANCREAS; INTESTINES; and the CENTRAL NERVOUS SYSTEM. Posttranslational processing of proglucagon is tissue-specific yielding numerous bioactive peptides.

Year introduced: 2007 (2006)

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Subheadings:

Tree Number(s): D06.472.317.680, D06.472.699.587.730, D12.644.548.586.730, D12.776.811.700

MeSH Unique ID: D052336

Registry Number: 55963-74-1

Entry Terms:

  • Pro-Glucagon
  • Pro Glucagon
  • Preproglucagon
  • Pre-Proglucagons
  • Preproglucagons
  • Glucagon Precursors
  • Glucagon Precursor

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