Ribosome Inactivating Proteins
N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity.
Year introduced: 2008(1988)
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Subheadings:
Tree Number(s): D08.811.277.450.430.700, D12.776.765.710
MeSH Unique ID: D054788
Registry Number: EC 3.2.2.22
Entry Terms:
- Inactivating Proteins, Ribosome
- Proteins, Ribosome Inactivating
- Polynucleotide Adenosine Glycosidase
- Adenosine Glycosidase, Polynucleotide
- Glycosidase, Polynucleotide Adenosine
- RIP (Ribosome Inactivating Proteins)
- RNA Glycosylase
- Glycosylase, RNA
- RNA N-Glycosidase
- N-Glycosidase, RNA
- RNA N Glycosidase
- rRNA N-Glycosylases
- N-Glycosylases, rRNA
- rRNA N Glycosylases
- RIP Ribosome Inactivating Proteins
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