Epoprostenol

A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).

Year introduced: 1991 (1978)

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Tree Number(s): D10.251.355.255.550.550.500, D23.469.050.175.725.550.500

MeSH Unique ID: D011464

Registry Number: DCR9Z582X0

Entry Terms:

• Prostacyclin
• Prostaglandin I(2)
• Prostaglandin I2
• Epoprostanol
• Epoprostenol Sodium
• Epoprostenol Sodium Salt, (5Z,9alpha,11alpha,13E,15S)-Isomer
• Flolan
• Veletri

Previous Indexing:

• Prostaglandins (1966-1977)

Pharmacologic Action:

• Antihypertensive Agents
• Platelet Aggregation Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Lipids
Fatty Acids
Fatty Acids, Unsaturated
Eicosanoids
Prostaglandins
Prostaglandins I
Epoprostenol

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Inflammation Mediators
Autacoids
Eicosanoids
Prostaglandins
Prostaglandins I
Epoprostenol