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gepotidacin [Supplementary Concept]
Date introduced: December 11, 2016
Topoisomerase Inhibitors
Compounds that inhibit the activity of DNA TOPOISOMERASES.
Year introduced: 2011
Hydrocarbons, Cyclic
Organic compounds composed exclusively of carbon and hydrogen forming a closed ring that may be either alicyclic or aromatic.
Year introduced: 1998
Heterocyclic Compounds, Fused-Ring
Multiple ring heterocyclic compounds containing two or more rings that share two atoms and one bond in common.
Year introduced: 2017
Acenaphthenes
Tricyclic ethylene-bridged naphthalene derivatives. They are found in petroleum residues and coal tar and used as dye intermediates, in the manufacture of plastics, and in insecticides and fungicides.
Year introduced: 1973(1972)
Heterocyclic Compounds
Cyclic compounds that include atoms other than carbon in their ring structure.
Heterocyclic Compounds, 3-Ring
A class of heterocyclic compounds that include a three-ring fused structure. Both aromatic or non-aromatic ring structures are included in this category.
Hydrocarbons
Organic compounds that primarily contain carbon and hydrogen atoms with the carbon atoms forming a linear or circular structure.
Hydrocarbons, Aromatic
Organic compounds containing carbon and hydrogen in the form of an unsaturated, usually hexagonal ring structure. The compounds can be single ring, or double, triple, or multiple fused rings.
Naphthalenes
Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.
Organic Chemicals
A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form.
Polycyclic Compounds
Compounds which contain two or more rings in their structure.
Year introduced: 2005(1974)
Polycyclic Aromatic Hydrocarbons
Aromatic hydrocarbons that contain extended fused-ring structures.
Year introduced: 2017(1996)
Chemical Actions and Uses
A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemicals. They are broken into actions, which describe their effects, and uses, which describe how they are employed.
Year introduced: 1999
Enzyme Inhibitors
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Year introduced: 1975(1964)
Antineoplastic Agents
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Pharmacologic Actions
A broad category of chemical actions and uses that result in the prevention, treatment, cure or diagnosis of disease. Included here are drugs and chemicals that act by altering normal body functions, such as the REPRODUCTIVE CONTROL AGENTS and ANESTHETICS. Effects of chemicals on the environment are also included.
Year introduced: 2004(1999)
Molecular Mechanisms of Pharmacological Action
Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY.
Year introduced: 2008(2004)
Therapeutic Uses
Uses of chemicals which affect the course of conditions, diseases, syndromes or pathology to benefit the health of an individual.
Year introduced: 2004