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Arabidopsis thaliana phytochelatin synthase 1 (PCS1) (CAD1), mRNA

NCBI Reference Sequence: NM_123774.4

FASTA Graphics 

LOCUS       NM_123774               1815 bp    mRNA    linear   PLN 20-OCT-2022
DEFINITION  Arabidopsis thaliana phytochelatin synthase 1 (PCS1) (CAD1), mRNA.
ACCESSION   NM_123774
VERSION     NM_123774.4
DBLINK      BioProject: PRJNA116
            BioSample: SAMN03081427
KEYWORDS    RefSeq.
SOURCE      Arabidopsis thaliana (thale cress)
  ORGANISM  Arabidopsis thaliana
            Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
            Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
            Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
            Camelineae; Arabidopsis.
REFERENCE   1  (bases 1 to 1815)
  AUTHORS   Tabata,S., Kaneko,T., Nakamura,Y., Kotani,H., Kato,T., Asamizu,E.,
            Miyajima,N., Sasamoto,S., Kimura,T., Hosouchi,T., Kawashima,K.,
            Kohara,M., Matsumoto,M., Matsuno,A., Muraki,A., Nakayama,S.,
            Nakazaki,N., Naruo,K., Okumura,S., Shinpo,S., Takeuchi,C., Wada,T.,
            Watanabe,A., Yamada,M., Yasuda,M., Sato,S., de la Bastide,M.,
            Huang,E., Spiegel,L., Gnoj,L., O'Shaughnessy,A., Preston,R.,
            Habermann,K., Murray,J., Johnson,D., Rohlfing,T., Nelson,J.,
            Stoneking,T., Pepin,K., Spieth,J., Sekhon,M., Armstrong,J.,
            Becker,M., Belter,E., Cordum,H., Cordes,M., Courtney,L.,
            Courtney,W., Dante,M., Du,H., Edwards,J., Fryman,J., Haakensen,B.,
            Lamar,E., Latreille,P., Leonard,S., Meyer,R., Mulvaney,E.,
            Ozersky,P., Riley,A., Strowmatt,C., Wagner-McPherson,C., Wollam,A.,
            Yoakum,M., Bell,M., Dedhia,N., Parnell,L., Shah,R., Rodriguez,M.,
            See,L.H., Vil,D., Baker,J., Kirchoff,K., Toth,K., King,L.,
            Bahret,A., Miller,B., Marra,M., Martienssen,R., McCombie,W.R.,
            Wilson,R.K., Murphy,G., Bancroft,I., Volckaert,G., Wambutt,R.,
            Dusterhoft,A., Stiekema,W., Pohl,T., Entian,K.D., Terryn,N.,
            Hartley,N., Bent,E., Johnson,S., Langham,S.A., McCullagh,B.,
            Robben,J., Grymonprez,B., Zimmermann,W., Ramsperger,U., Wedler,H.,
            Balke,K., Wedler,E., Peters,S., van Staveren,M., Dirkse,W.,
            Mooijman,P., Lankhorst,R.K., Weitzenegger,T., Bothe,G., Rose,M.,
            Hauf,J., Berneiser,S., Hempel,S., Feldpausch,M., Lamberth,S.,
            Villarroel,R., Gielen,J., Ardiles,W., Bents,O., Lemcke,K.,
            Kolesov,G., Mayer,K., Rudd,S., Schoof,H., Schueller,C.,
            Zaccaria,P., Mewes,H.W., Bevan,M. and Fransz,P.
  CONSRTM   Kazusa DNA Research Institute; Cold Spring Harbor and Washington
            University in St Louis Sequencing Consortium; European Union
            Arabidopsis Genome Sequencing Consortium
  TITLE     Sequence and analysis of chromosome 5 of the plant Arabidopsis
            thaliana
  JOURNAL   Nature 408 (6814), 823-826 (2000)
   PUBMED   11130714
REFERENCE   2  (bases 1 to 1815)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 1815)
  AUTHORS   Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
            Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
            Vaughn,M. and Town,C.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute,
            9704 Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Protein update by submitter
REFERENCE   4  (bases 1 to 1815)
  AUTHORS   Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E.
  CONSRTM   TAIR
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2011) Department of Plant Biology, Carnegie
            Institution, 260 Panama Street, Stanford, CA, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by TAIR and Araport.
            This record is derived from an annotated genomic sequence
            (NC_003076).
            
            On Sep 12, 2016 this sequence version replaced NM_123774.3.
FEATURES             Location/Qualifiers
     source          1..1815
                     /organism="Arabidopsis thaliana"
                     /mol_type="mRNA"
                     /db_xref="taxon:3702"
                     /chromosome="5"
                     /ecotype="Columbia"
     gene            1..1815
                     /gene="CAD1"
                     /locus_tag="AT5G44070"
                     /gene_synonym="ARA8; ARABIDOPSIS THALIANA PHYTOCHELATIN
                     SYNTHASE 1; ATPCS1; CADMIUM SENSITIVE 1; MRH10.18;
                     MRH10_18; PCS1; PHYTOCHELATIN SYNTHASE; PHYTOCHELATIN
                     SYNTHASE 1"
                     /note="Phytochelatin synthase gene confers tolerance to
                     cadmium ions. Catalyzes phytochelatin (PC) synthesis from
                     glutathione (GSH) in the presence of Cd2+, Zn2+, Cu2+ and
                     Fe3+, but not by Co2+ or Ni2+."
                     /db_xref="Araport:AT5G44070"
                     /db_xref="GeneID:834430"
                     /db_xref="TAIR:AT5G44070"
     CDS             171..1628
                     /gene="CAD1"
                     /locus_tag="AT5G44070"
                     /gene_synonym="ARA8; ARABIDOPSIS THALIANA PHYTOCHELATIN
                     SYNTHASE 1; ATPCS1; CADMIUM SENSITIVE 1; MRH10.18;
                     MRH10_18; PCS1; PHYTOCHELATIN SYNTHASE; PHYTOCHELATIN
                     SYNTHASE 1"
                     /inference="Similar to RNA sequence,
                     EST:INSD:AV526117.1,INSD:AV562203.1,INSD:EL009460.1,
                     INSD:ES195192.1,INSD:EG470564.1,INSD:EL331779.1,
                     INSD:ES172251.1,INSD:DR347043.1,INSD:ES096721.1,
                     INSD:DR347035.1,INSD:EL058944.1,INSD:AV821622.1,
                     INSD:AV538749.1,INSD:EL262415.1,INSD:BP576052.1,
                     INSD:EL188746.1,INSD:BP581751.1,INSD:DR347042.1,
                     INSD:EL248440.1,INSD:AV793727.1,INSD:EL006564.1,
                     INSD:EL291851.1,INSD:EL263238.1,INSD:EH836707.1,
                     INSD:BP563228.1,INSD:BP632687.1,INSD:EG470635.1,
                     INSD:AV526107.1,INSD:EG470566.1,INSD:BP868419.1,
                     INSD:EL149933.1,INSD:BP622382.1,INSD:BP606352.1,
                     INSD:BP589967.1,INSD:DR347040.1,INSD:BP669465.1,
                     INSD:AI995885.1,INSD:BP668203.1,INSD:DR347048.1,
                     INSD:DR347047.1,INSD:EH821481.1,INSD:BP866345.1,
                     INSD:DR347041.1,INSD:EL047588.1,INSD:AV551060.1,
                     INSD:BP561535.1,INSD:BP664697.1,INSD:ES194183.1,
                     INSD:EH883676.1,INSD:BP572753.1,INSD:EH799722.1,
                     INSD:AV520044.1,INSD:EL198815.1,INSD:EG470636.1,
                     INSD:EH876962.1,INSD:DR347050.1,INSD:DR347049.1,
                     INSD:BE662956.1,INSD:BU636703.1,INSD:EH838089.1,
                     INSD:AV782133.1,INSD:EH858210.1,INSD:DR381517.1,
                     INSD:DR347044.1,INSD:AV536560.1,INSD:BP666345.1,
                     INSD:BP778309.1,INSD:EL232794.1,INSD:EH885925.1,
                     INSD:EL008813.1,INSD:EL275935.1,INSD:BP801361.1,
                     INSD:ES203481.1,INSD:BP790452.1,INSD:CB263626.1,
                     INSD:EL010804.1,INSD:BP794880.1,INSD:DR347037.1,
                     INSD:DR347036.1,INSD:BP868498.1,INSD:EL101328.1,
                     INSD:DR347045.1,INSD:DR338861.1,INSD:EH852469.1,
                     INSD:DR347034.1,INSD:EH875306.1,INSD:BP595762.1,
                     INSD:DR347038.1,INSD:DR374388.1,INSD:BP862356.1,
                     INSD:DR347039.1,INSD:BP858088.1"
                     /inference="similar to RNA sequence,
                     mRNA:INSD:AF085230.1,INSD:AY048257.1,INSD:AY079384.1,
                     INSD:EU218538.1,INSD:BX830828.1,INSD:AF135155.1,
                     INSD:BX833258.1,INSD:AF461180.1,INSD:AF162689.1,
                     INSD:AF093753.1,INSD:AY039951.1"
                     /note="CADMIUM SENSITIVE 1 (CAD1); FUNCTIONS IN: cadmium
                     ion binding, copper ion binding, glutathione
                     gamma-glutamylcysteinyltransferase activity; INVOLVED IN:
                     in 6 processes; LOCATED IN: cytosol; EXPRESSED IN: 24
                     plant structures; EXPRESSED DURING: 13 growth stages;
                     CONTAINS InterPro DOMAIN/s: Phytochelatin synthase,
                     C-terminal (InterPro:IPR015407), Phytochelatin synthase
                     (InterPro:IPR007719); BEST Arabidopsis thaliana protein
                     match is: phytochelatin synthase 2 (TAIR:AT1G03980.1); Has
                     1807 Blast hits to 1807 proteins in 277 species: Archae -
                     0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385;
                     Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink)."
                     /codon_start=1
                     /product="phytochelatin synthase 1 (PCS1)"
                     /protein_id="NP_199220.1"
                     /db_xref="GeneID:834430"
                     /db_xref="TAIR:AT5G44070"
                     /db_xref="Araport:AT5G44070"
                     /translation="MAMASLYRRSLPSPPAIDFSSAEGKLIFNEALQKGTMEGFFRLI
                     SYFQTQSEPAYCGLASLSVVLNALSIDPGRKWKGPWRWFDESMLDCCEPLEVVKEKGI
                     SFGKVVCLAHCSGAKVEAFRTSQSTIDDFRKFVVKCTSSENCHMISTYHRGVFKQTGT
                     GHFSPIGGYNAERDMALILDVARFKYPPHWVPLKLLWEAMDSIDQSTGKRRGFMLISR
                     PHREPGLLYTLSCKDESWIEIAKYLKEDVPRLVSSQHVDSVEKIISVVFKSLPSNFNQ
                     FIRWVAEIRITEDSNQNLSAEEKSRLKLKQLVLKEVHETELFKHINKFLSTVGYEDSL
                     TYAAAKACCQGAEILSGSPSKEFCCRETCVKCIKGPDDSEGTVVTGVVVRDGNEQKVD
                     LLVPSTQTECECGPEATYPAGNDVFTALLLALPPQTWSGIKDQALMHEMKQLISMASL
                     PTLLQEEVLHLRRQLQLLKRCQENKEEDDLAAPAY"
ORIGIN      
        1 aataattgag tgagtctgta tattaaatac gcaaatcatc atcttcccaa tttcgaatct
       61 cacacaccga aagttatttt cgaatccact aacgaatctt ccacagcaaa cacttttgtg
      121 ttcctctgta atttctcagt atatatagat accaaaacaa gcagtgaaaa atggctatgg
      181 cgagtttata tcggcgatct cttccttctc ctccggccat tgacttttct tccgccgaag
      241 gcaagctaat cttcaatgaa gcgcttcaga aaggaactat ggaaggattt ttcaggttga
      301 tttcgtattt tcagacacaa tccgaacctg cgtattgtgg tttggctagt ctctcagtgg
      361 tgttgaatgc tctttctatc gatcctggac gtaaatggaa agggccttgg aggtggtttg
      421 atgaatcaat gttggattgc tgcgaacctc tggaagtagt gaaggaaaaa ggcatttcat
      481 ttggaaaagt tgtctgtttg gctcattgtt caggagcaaa agttgaggct ttccgtacaa
      541 gtcagagcac cattgatgat ttccgcaaat ttgtcgtcaa atgcacgagt tctgagaatt
      601 gtcatatgat ctcaacatat caccgaggtg tatttaagca gactgggact ggtcactttt
      661 cacctattgg tggctataat gctgagagag atatggcttt gattcttgat gttgctcgtt
      721 tcaagtatcc ccctcactgg gttcctctta aacttctttg ggaagccatg gacagtattg
      781 atcagtcaac agggaaacgt agagggttca tgctcatatc tagaccacac agagaacccg
      841 gattgctcta tactctgagc tgcaaggatg aaagctggat cgaaatagcc aagtatttga
      901 aggaagatgt tcctcgtctt gtaagttcac agcatgtaga ttctgtggag aaaatcatat
      961 cagttgtgtt caagtcactt ccatcaaatt tcaaccaatt catcagatgg gtggctgaga
     1021 tccgaattac agaggactca aaccaaaatc tcagcgcaga ggagaagtct aggctgaaac
     1081 taaagcaatt ggtgctgaag gaagtgcacg aaactgaact gttcaaacac atcaataagt
     1141 tcttatccac agtgggttat gaagacagtc tgacttatgc tgctgcaaag gcttgttgcc
     1201 aaggagctga aatcttatcc ggaagcccat caaaagagtt ttgttgtcgg gaaacttgcg
     1261 tgaaatgcat caaaggtcct gatgactctg aaggcacggt ggtgactgga gttgtggtgc
     1321 gtgatgggaa tgaacaaaag gttgatctgt tagtgccatc gacgcaaact gagtgtgaat
     1381 gtggtcctga agcaacttat ccagcaggaa acgatgtgtt cactgcactt ctattggctt
     1441 tacctccaca gacatggtca gggatcaaag accaagctct tatgcatgaa atgaagcagc
     1501 tcatttccat ggcttccctc ccaactttgc ttcaagaaga ggtattgcat cttcgacggc
     1561 aacttcagct gctaaaacga tgccaagaga acaaggaaga ggatgatctc gctgctcctg
     1621 cctattagtt cattgtccca aatcctctct cttccccatt tgaatcccac gttctcaaca
     1681 cttaattgtt agaaagtctc tttattctct gtacgattca aactctattt gcaatgagag
     1741 atatatgtaa cttgcattct ataaattgtt aatcacaata agttaagaat cctagaatca
     1801 tatttcatca cactc
//
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