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Homo sapiens mRNA for protein phosphatase 1B2 (PPM1B2 gene)

GenBank: AJ271832.1

FASTA Graphics 

LOCUS       AJ271832                2586 bp    mRNA    linear   PRI 07-OCT-2008
DEFINITION  Homo sapiens mRNA for protein phosphatase 1B2 (PPM1B2 gene).
ACCESSION   AJ271832
VERSION     AJ271832.1
KEYWORDS    alternative splicing; PPM1B2 gene; protein phosphatase 1B2.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1
  AUTHORS   Seroussi,E., Shani,N., Hayut,A., Faier,S., Ben-Meir,D.,
            Divinski,I., Smorodinsky,N.I. and Lavi,S.
  TITLE     Protein phosphatase 1B. Cloning and characterization of two major
            transcripts generated by alternative use of 3' exons
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2586)
  AUTHORS   Seroussi,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2000) Seroussi E., Department of Cell Research
            and Immunology, Tel Aviv Universit, George Wise Faculty of Life
            Sciences, Tel Aviv University, Tel Aviv, 69978, ISRAEL
FEATURES             Location/Qualifiers
     source          1..2586
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     gene            1..2586
                     /gene="PPM1B2"
     exon            1..379
                     /gene="PPM1B2"
                     /number=1
     exon            380..1239
                     /gene="PPM1B2"
                     /number=2
     CDS             394..1833
                     /gene="PPM1B2"
                     /function="phophatase"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="previously named PP2C-beta gene;
                     alternative splice variant"
                     /codon_start=1
                     /product="protein phosphatase 1B2 53 kDa isoform"
                     /protein_id="CAC27992.1"
                     /db_xref="GDB:136856"
                     /db_xref="GOA:O75688"
                     /db_xref="HGNC:HGNC:9276"
                     /db_xref="InterPro:IPR000222"
                     /db_xref="InterPro:IPR001932"
                     /db_xref="InterPro:IPR012911"
                     /db_xref="InterPro:IPR014045"
                     /db_xref="InterPro:IPR015655"
                     /db_xref="PDB:2P8E"
                     /db_xref="UniProtKB/Swiss-Prot:O75688"
                     /translation="MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVV
                     GIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENV
                     KNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNG
                     QVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQ
                     LVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVV
                     DTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPD
                     LAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDEAEESGSQGKL
                     VEALRQMRINHRGNYRQLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQ
                     ESHTESESGLAELDSSNEDAGTKMSGEKI"
     exon            1240..1357
                     /gene="PPM1B2"
                     /number=3
     exon            1358..1469
                     /gene="PPM1B2"
                     /number=4
     exon            1470..1527
                     /gene="PPM1B2"
                     /number=5
     exon            1528..2586
                     /gene="PPM1B2"
                     /note="alternatively spliced exon"
                     /number=7
     regulatory      2560..2565
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PPM1B2"
ORIGIN      
        1 ggcggaaaag ccgccggtgc tctgacggcc tcgttcccct agcagttgcg ggggagtttc
       61 ctgccggcgc ggctggagtc tctgattctc agggttcggt ggttggaaga tgctccagag
      121 agacgaggct gcggcggagg aggtggcggc ggccgaatcg gcaacggcgc tagggtggag
      181 agaaggcggc agcggcggcg gcggcggcgt gaggggccgg gcggtgtaaa cagccccgga
      241 ggcggcggag gcggcggtcg agaccccgag ggggaagcgg cggctgagtc agggtcgcgc
      301 ctccgttgga aacttgggct gagtaccgcg gcgggcgcga gcgaggcgcc ctagacatct
      361 tctccctccc ttgcctcaga cttattgcaa aacatgggtg catttttgga taaacccaaa
      421 actgaaaaac ataatgctca tggtgctggg aatggtttac gttatggcct gagcagcatg
      481 caaggatgga gagtggaaat ggaagatgca cacacagctg ttgtaggtat tcctcacggc
      541 ttggaagact ggtcattttt tgcagtttat gatggtcatg ctggatcccg agtggcaaat
      601 tactgctcaa cacatttatt agaacacatc actactaacg aagactttag ggcagctgga
      661 aaatcaggat ctgctcttga gctttcagtg gaaaatgtta agaatggtat cagaactgga
      721 tttttgaaaa ttgatgaata catgcgtaac ttttcagacc tcagaaacgg gatggacagg
      781 agtggttcaa ctgcagtggg agttatgatt tcacctaagc atatctactt tatcaactgt
      841 ggtgattcac gtgctgttct gtataggaat ggacaagtct gcttttctac ccaggatcac
      901 aaaccttgca atccaaggga aaaggagcga atccaaaatg caggaggcag cgtgatgata
      961 caacgtgtta atggttcatt agcagtatct cgtgctctgg gggactatga ttacaagtgt
     1021 gttgatggca agggcccaac agaacaactt gtttctccag agcctgaggt ttatgaaatt
     1081 ttaagagcag aagaggatga atttatcatc ttggcttgtg atgggatctg ggatgttatg
     1141 agtaatgagg agctctgtga atatgttaaa tctaggcttg aggtatctga tgacctggaa
     1201 aatgtgtgca attgggtagt ggacacttgt ttacacaagg gaagtcgaga taacatgagt
     1261 attgtactag tttgcttttc aaatgctccc aaggtctcag atgaagcggt gaaaaaagat
     1321 tcagagttgg ataagcactt ggaatcacgg gttgaagaga ttatggagaa gtctggcgag
     1381 gaaggaatgc ctgatcttgc ccatgtcatg cgcatcttgt ctgcagaaaa tatcccaaat
     1441 ttgcctcctg ggggaggtct tgctggcaag cgtaatgtta ttgaagctgt ttatagtaga
     1501 ctgaatccac atagagaaag tgatggggcc tccgatgaag cagaggaaag tggatcacag
     1561 ggaaaattgg tggaagctct caggcaaatg agaattaatc ataggggaaa ctaccgacaa
     1621 cttctggagg agatgctgac tagttacagg ctagctaaag tagagggaga agaaagccct
     1681 gctgaaccag ctgccacagc tacttcttcg aacagtgatg ctggaaaccc agtgacaatg
     1741 caggaaagcc atactgaatc agaaagtggt cttgctgaat tagacagctc taatgaagat
     1801 gcagggacaa agatgagtgg tgaaaaaata tgactttcct ttttggtaat atttttgtga
     1861 tctttgatgg tttttaacct aggaagtgta atgtatgcat ttatataact gttttgttat
     1921 ttgaatcttg gaaaactagt tttattatat tcagatagcc ttgtttttta aaaaggcctt
     1981 tgcatacacc tttatgagat agtgtaaaat tgactattta tagtactatg gatttaatga
     2041 aattatatgt catttcacat tgtatgccag aaattaggct accaattatg aattaaagtc
     2101 agtagttaaa ttaatactag atagaattag aaattttgat tagagagatt atgctatatt
     2161 atggaaaaac ttgttaatgt agaattatac tgcttcatat tattttacct attagtacac
     2221 tcatagttag ctttgtaata aatttatgtt ttctttaata attttagttc ttcaaagaat
     2281 ggctgatgct ggcctgtaat ttttctttca aggatgataa tttgtgtgtt gtttgatttg
     2341 tttatatttt acatctctgt agttttattt ttagaagttg tgagatattg gatgtgtggc
     2401 tatttttcct ttctctgtat tctttatgaa acataacttt tgaaaaacct atgtattatt
     2461 catacagctt tggtttgtat attctgtata gcctaactac acacatcaaa atgtatgtca
     2521 accaagtgtt tagaatgaaa ttataagtgt ttaagtccaa ataaagcatg tgatgtggaa
     2581 taatct
//
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