LOCUS BC003834 1974 bp mRNA linear ROD 03-OCT-2003
DEFINITION Mus musculus F-box and WD-40 domain protein 2, mRNA (cDNA clone
MGC:6266 IMAGE:3601733), complete cds.
ACCESSION BC003834
VERSION BC003834.1
KEYWORDS MGC.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 1974)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1974)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (28-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Gilbert Smith, Ph.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 11 Row: l Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13937386.
FEATURES Location/Qualifiers
source 1..1974
/organism="Mus musculus"
/mol_type="mRNA"
/strain="FVB/N"
/db_xref="taxon:10090"
/clone="MGC:6266 IMAGE:3601733"
/tissue_type="Mammary tumor. Metallothionien-TGF alpha
model. 10 month old virgin mouse. Taken by biopsy."
/clone_lib="NCI_CGAP_Mam1"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1974
/gene="Fbxw2"
/gene_synonym="FBW2"
/gene_synonym="Fwd2"
/gene_synonym="MD6"
/db_xref="GeneID:30050"
/db_xref="MGI:MGI:1353435"
CDS 280..1017
/gene="Fbxw2"
/gene_synonym="FBW2"
/gene_synonym="Fwd2"
/gene_synonym="MD6"
/codon_start=1
/product="Fbxw2 protein"
/protein_id="AAH03834.1"
/db_xref="GeneID:30050"
/db_xref="MGI:MGI:1353435"
/translation="MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHL
SNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTAC
KNLGWQIDDSVQDSLHWKKVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGL
LCTGSDDLSAKLWDVSTGQCVYGIQTHTSAAVKFDEQKLVTGSFDNTVACWEWSSGAR
TQHFRGHTGAGVFSFFKNLYSYFSHAL"
misc_feature 661..960
/gene="Fbxw2"
/gene_synonym="FBW2"
/gene_synonym="Fwd2"
/gene_synonym="MD6"
/note="COG2319; Region: FOG: WD40 repeat [General function
prediction only]"
/db_xref="CDD:COG2319"
ORIGIN
1 aagcagtacc ggtacttgga gggcagagac ggaagtagag ccgcttccgc ccgacgctgg
61 gcgccggaat ggcgcgcgga gatgacgcag cagcaccgga agccgctccc ctgtgaggct
121 gcggacccag agcagcggcc gtaggtccag gcgccatggc tgtggagcgg acccggccgc
181 tgcgacgctc tggcggcccg agcgcgccta gtcggtgtga gcccggcgcg aggtcccggg
241 ccccggggcg ctcgctcagg taaatatttc cataacctta tggagagaaa ggactttgag
301 acatggcttg ataacatttc tgttacattt ctttctctga cggacttgca gaaaaatgaa
361 actctggacc acctgattag tctgagtggg gcagtccagc tcaggcatct ctccaataac
421 ctggagactc tcctcaagcg ggacttcctc aaactccttc ccctggagct cagtttttat
481 ttgttaaaat ggctcgatcc tcagacttta ctcacatgct gcctggtctc taagcagtgg
541 aataaggtga taagtgcctg tacagaggtg tggcagactg catgtaaaaa tttgggctgg
601 cagatagatg attctgttca ggactcattg cactggaaga aggtttattt gaaggctatt
661 ttgaggatga agcaactgga ggaccatgaa gcctttgaga cctcttcgtt aattggacat
721 agtgccagag tgtatgcact ttactacaaa gatggacttc tctgtacagg gtcagatgac
781 ttgtctgcaa agctgtggga tgtaagcaca gggcagtgtg tttacggcat ccagacccac
841 acttctgcag ctgtgaagtt cgatgaacag aagcttgtga caggctcctt tgacaacact
901 gtggcctgct gggagtggag ttccggagcc aggacccagc acttccgggg gcacacgggg
961 gcgggtgtgt tctccttttt caagaatctt tacagttact ttagccatgc cttgtaagac
1021 taagagtcaa atatttaagg tggttttttg tttgtttgtt cttttggggg ggggtggcgg
1081 cttgcttact tgcttttaat ctagcatttt ctctttttaa ccactgaagc tattttcttg
1141 cattttagtt acttacattt gggatgtatt tgcttttctt ttagccttgt aaacactctt
1201 tatgtatgct ggaaggagca gctgtccttc tctcccagtg catttctctc ttgctacaca
1261 gtcatatttg ttttttagtg gactccacac tactacactt agacatttag accactccac
1321 ttacaaattt agagctgaaa acccctgggc acaaggtggt tcactgactg tatgatcttc
1381 acagagtact tgcagttagt ggttggctgc taagtgagta aaacaagcaa caccctgggc
1441 tatcaggata ccttgtttat cccgagtttc ttaagttgta cctgatgctt agtatttttt
1501 ttttttatct aactcttaca aaacactcct ccaattaaac tcatattaaa aaaaattttt
1561 ttaatctgtt cttatttaga aatctatggt ttgtagccaa gtgtagtgga acacacattt
1621 aatcccagca cttggtagac agaggctggc agatctctgg gtttgaggcc agcctggtca
1681 acatagcgag ttccaggaca gcagagctat atggagaaac cctgtctcaa aaagcaaaca
1741 aaagaaaaat ctatggctta gtacagaccc catccattag agtaatacca cacagcctaa
1801 ggacaccaca gcttctaggt gatttcattc cttacctcta aaaaggcttc ttgacacctc
1861 tgagctttta atccatgcct ttgctgtctg ctctacctga agcatctttt tattttctta
1921 ataaactata cacatccttc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
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