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Homo sapiens olfactory receptor family 52 subfamily E member 4 (OR52E4), mRNA

NCBI Reference Sequence: NM_001005165.2

FASTA Graphics 

LOCUS       NM_001005165            2947 bp    mRNA    linear   PRI 26-OCT-2024
DEFINITION  Homo sapiens olfactory receptor family 52 subfamily E member 4
            (OR52E4), mRNA.
ACCESSION   NM_001005165 XM_372368
VERSION     NM_001005165.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2947)
  AUTHORS   Malnic,B., Godfrey,P.A. and Buck,L.B.
  TITLE     The human olfactory receptor gene family
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2584-2589 (2004)
   PUBMED   14983052
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 May 4;101(18):7205]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131574.4.
            
            On Aug 5, 2020 this sequence version replaced NM_001005165.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641726.1/ ENSP00000493085.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                AC131574.4         20294-20379         c
            87-2947             AC131574.4         13929-16789         c
FEATURES             Location/Qualifiers
     source          1..2947
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.4"
     gene            1..2947
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /note="olfactory receptor family 52 subfamily E member 4"
                     /db_xref="GeneID:390081"
                     /db_xref="HGNC:HGNC:15213"
     exon            1..86
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /inference="alignment:Splign:2.1.0"
     exon            87..2947
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    92..94
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /note="upstream in-frame stop codon"
     CDS             161..1099
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /note="olfactory receptor OR11-55"
                     /codon_start=1
                     /product="olfactory receptor 52E4"
                     /protein_id="NP_001005165.1"
                     /db_xref="CCDS:CCDS31401.1"
                     /db_xref="GeneID:390081"
                     /db_xref="HGNC:HGNC:15213"
                     /translation="MPSINDTHFYPPFFLLLGIPGLDTLHIWISFPFCIVYLIAIVGN
                     MTILFVIKTEHSLHQPMFYFLAMLSMIDLGLSTSTIPKMLGIFWFNLQEISFGGCLLQ
                     MFFIHMFTGMETVLLVVMAYDRFVAICNPLQYTMILTNKTISILASVVVGRNLVLVTP
                     FVFLILRLPFCGHNIVPHTYCEHRGLAGLACAPIKINIIYGLMVISYIIVDVILIASS
                     YVLILRAVFRLPSQDVRLKAFNTCGSHVCVMLCFYTPAFFSFMTHRFGQNIPHYIHIL
                     LANLYVVVPPALNPVIYGVRTKQIREQIVKIFVQKE"
     misc_feature    173..175
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q8NGH9.1); glycosylation site"
     misc_feature    242..304
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGH9.1);
                     transmembrane region"
     misc_feature    329..391
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGH9.1);
                     transmembrane region"
     misc_feature    464..526
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGH9.1);
                     transmembrane region"
     misc_feature    584..646
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGH9.1);
                     transmembrane region"
     misc_feature    755..814
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGH9.1);
                     transmembrane region"
     misc_feature    875..937
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGH9.1);
                     transmembrane region"
     misc_feature    983..1045
                     /gene="OR52E4"
                     /gene_synonym="OR11-55"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NGH9.1);
                     transmembrane region"
ORIGIN      
        1 ggggaaccta atcacggtct ttaagaacct ggactcatgc tccaattctg ctccaagtga
       61 gggctgggag aagaaatatt acagaggaac ttgacaagag aggaccttaa agaaagtgag
      121 atccttcata cttaggaatt cagtgacact tgctgggaga atgccttcta tcaatgacac
      181 ccacttctat ccccccttct tcctcctgct aggaatacca ggactggaca ctttacatat
      241 ctggatttct ttcccattct gtattgtgta cctgattgcc attgtgggga atatgaccat
      301 tctctttgtg atcaaaactg aacatagtct acaccagccc atgttctact tcctggccat
      361 gttgtctatg attgatctgg gtctgtccac atccactatc cccaaaatgc taggaatctt
      421 ctggttcaac ctccaagaga tcagctttgg gggatgcctt cttcagatgt tctttattca
      481 catgtttaca ggcatggaga ctgttctgtt ggtggtcatg gcttatgacc gctttgttgc
      541 catctgcaac cctctccagt acaccatgat cctcaccaat aaaaccatca gtatcctagc
      601 ttctgtggtt gttggaagaa atttagttct tgtaacccca tttgtgtttc tcattctgcg
      661 tctgccattc tgtgggcata acatcgtacc tcacacatac tgtgagcaca ggggtctggc
      721 cgggttggcc tgtgcaccca ttaagatcaa cataatctat gggctcatgg tgatttctta
      781 tattattgtg gatgtgatct taattgcctc ttcctatgtg cttatcctta gagctgtttt
      841 tcgccttccc tctcaagatg tccgactaaa ggccttcaat acctgtggtt ctcatgtctg
      901 tgttatgctg tgcttttaca caccagcatt tttttctttt atgacacatc gttttggcca
      961 aaacattccc cactatatcc atattctttt ggctaacctg tatgtggttg tcccacctgc
     1021 ccttaaccct gtcatttatg gagtcaggac caagcagatc cgagagcaaa ttgtgaaaat
     1081 atttgtacag aaagaataat tctgtattaa agtttggata aatatatcta tatacaaccc
     1141 aaattatcat catctgagct ccctttttaa tcttctgtaa cagttggtca tgcttgtcag
     1201 attttttcct tttgactgga agtgctttag tgttgacaga taatgcaaac ttaaaacctt
     1261 tgctgcctgt ttcccctact tctctccaag tacctggaca aaggttagag attaatggag
     1321 aaggtaacta tgctgaaggt tgaggtggct ttggagtaga actgcttgta aacaagggtg
     1381 ataggtagct ccattttttt ccatatgtct tctctctagg taagtttaga tcctgaagga
     1441 tactgatcaa ataaatctca ttttatagat gaacaaaata agctgtaatc cagcagtagt
     1501 gtccgtttca tagctttgta ttctttacag aatccaaaat tttgttgttc ttctccaaaa
     1561 tctttgactc ccatgtttat tttaatgctc tctcagtctt gctgttactg ccatttttgc
     1621 tcctttcctt ctttcagatt cctgctctct ctctttttgt gatggttaat actgagtgtc
     1681 aactttattt gactgaagga tacaaagtat tgatcctggt tttgtctgtg agggtgttgc
     1741 caaaagagat taacatttga gtcagtgggc tgggaaaggc agacccacct tcaatctggg
     1801 tgggcaccat ctaatcagct gccaacgcag ctagaatata aagcaggcag aaaaatgtga
     1861 aaagactaga tgggcctagc ctcccaggct acatccttct cctgtgctgg atgcttcctc
     1921 ctcgaacgtc ggactccaag ttcctcagtt ttgggactca gagtggctct ccttgatctt
     1981 cagcttgcag atggcctatt gtgggacctt gtgatcatgt gagttaatac ttaattcccc
     2041 ctttgtgtgt gtgtgtatgt gtacacacac acacacacac acacacatat atatatatat
     2101 cctattagtt cagtccctct agagaacact gactaataca cttttctttt acattcgttc
     2161 tctgataaag taagtctttg tgaatttagg gatatgagag actacagtgt gggtattacg
     2221 gagacatgtt ttctcacttg aagcaaagtc attttagatg tgactacttg tatgtgtcgc
     2281 ctgtctaatt ctaattctca attctatctg acaatttccc ttcagacaaa atatataaaa
     2341 cttatgagac tttataaaac ttagaaaaac aattaggctc aagctatggt aagcacaggg
     2401 ccagacttga tatcgacttc aaaataatat cattataatt tattaatcct gtagatctcc
     2461 aatatttagt cctattttca aacttcagat atggctggag aatgtggttt gctttaaaat
     2521 agataaaaga gacattgaac tgaaatttgt gacttatcag ggtactcatg cttcaaaatc
     2581 agaagaagtc tccctcatgt tctataattt agaaccactg tgtagtttgt atgacaatat
     2641 acaaaatact caaaagtacg cagataacga ttttaggaaa tgggggcgga tatagccaag
     2701 tagacaagaa aagcaacatc acctattcag tatctgtgaa tctggacagt tcttggtctt
     2761 aacactggct aagcacaatt cctgaattct atagtatttt gtagattttc tttaggtctg
     2821 tatgcatggg ttctaatttg atttttgcag cttctgcttc atgtacttaa cattttatgg
     2881 gaacataggg ttttaaatgt ggaaatacat tgaaacttga tctattccct ttgtcttaca
     2941 aataaaa
//
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