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PREDICTED: Homo sapiens potassium voltage-gated channel subfamily H member 6 (KCNH6), transcript variant X4, mRNA

NCBI Reference Sequence: XM_017025178.3

FASTA Graphics 

LOCUS       XM_017025178            3725 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens potassium voltage-gated channel subfamily H
            member 6 (KCNH6), transcript variant X4, mRNA.
ACCESSION   XM_017025178
VERSION     XM_017025178.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017025178.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3725
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..3725
                     /gene="KCNH6"
                     /gene_synonym="ERG-2; ERG2; hERG-2; HERG2; Kv11.2"
                     /note="potassium voltage-gated channel subfamily H member
                     6; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 26 ESTs, 7 long SRA reads, 14 Proteins, and
                     96% coverage of the annotated genomic feature by RNAseq
                     alignments, including 7 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:81033"
                     /db_xref="HGNC:HGNC:18862"
                     /db_xref="MIM:608168"
     CDS             57..2900
                     /gene="KCNH6"
                     /gene_synonym="ERG-2; ERG2; hERG-2; HERG2; Kv11.2"
                     /codon_start=1
                     /product="potassium voltage-gated channel subfamily H
                     member 6 isoform X4"
                     /protein_id="XP_016880667.1"
                     /db_xref="GeneID:81033"
                     /db_xref="HGNC:HGNC:18862"
                     /db_xref="MIM:608168"
                     /translation="MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYC
                     NDGFCELFGYSRVEVMQQPCTCDFLTGPNTPSSAVSRLAQALLGAEECKVDILYYRKD
                     ASSFRCLVDVVPVKNEDGAVIMFILNFEDLAQLLAKCSSRSLSQRLLSQSFLGSEGSH
                     GRPGGPGPGTGRGKYRTISQIPQFTLNFVEFNLEKHRSSSTTEIEIIAPHKVVERTQN
                     VTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPY
                     SAAFLLSDQDESRRGACSYTCSPLTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHP
                     RRIAVHYFKGWFLIDMVAAIPFDLLIFRTGSDETTTLIGLLKTARLLRLVRVARKLDR
                     YSEYGAAVLFLLMCTFALIAHWLACIWYAIGNVERPYLEHKIGWLDSLGVQLGKRYNG
                     SDPASGPSVQDKYVTALYFTFSSLTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIF
                     GNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMN
                     AVLKGFPECLQADICLHLHRALLQHCPAFSGAGKGCLRALAVKFKTTHAPPGDTLVHL
                     GDVLSTLYFISRGSIEILRDDVVVAILGKNDIFGEPVSLHAQPGKSSADVRALTYCDL
                     HKIQRADLLEVLDMYPAFAESFWSKLEVTFNLRDAPGSQDHQGFFLSDNQSDAAPPLS
                     ISDASGLWPELLQEMPPRHSPQSPQEDPDCWPLKLGSRLEQLQAQMNRLESRVSSDLS
                     RILQLLQKPMPQGHASYILEAPASNDLALVPIASETTSPGPRLPQGFLPPAQTPSYGD
                     LDDCSPKHRNSSPRMPHLAVATDKTLAPSSEQEQPEGLWPPLASPLHPLEVQGLICGP
                     CFSSLPEHLGSVPKQLDFQRHGSDPGFAGSWGH"
ORIGIN      
        1 ggagacgccg ggagccagtg gcgcctgtgg ctccgggcag gggccgcggc cgaaagatgc
       61 cggtccgcag gggccacgtc gctccccaaa acacttacct ggacaccatc atccgcaagt
      121 tcgagggcca aagtcggaag ttcctgattg ccaatgctca gatggagaac tgcgccatca
      181 tttactgcaa cgacggcttc tgcgaactct tcggctactc ccgagtggag gtgatgcagc
      241 aaccctgcac ctgcgacttc ctcacaggcc ccaacacacc aagcagcgcc gtgtcccgcc
      301 tagcgcaggc cctgctgggg gctgaggagt gcaaggtgga catcctctac taccgcaagg
      361 atgcctccag cttccgctgc ctggtagatg tggtgcccgt gaagaacgag gacggggctg
      421 tcatcatgtt cattctcaac ttcgaggacc tggcccagct cctggccaag tgcagcagcc
      481 gcagcttgtc ccagcgcctg ttgtcccaga gcttcctggg ctccgagggc tctcatggca
      541 ggccaggcgg accagggcca ggcacaggca ggggcaagta caggaccatc agccagatcc
      601 cacagttcac gctcaacttc gtggagttca acttggagaa gcaccgctcc agctccacca
      661 cggagattga gatcatcgcg ccccataagg tggtggagcg gacacagaac gtcactgaga
      721 aggtcaccca ggtcctgtcc ctgggcgcgg atgtgctgcc ggagtacaag ctgcaggcgc
      781 cgcgcatcca ccgctggacc atcctgcact acagcccctt caaggccgtg tgggactggc
      841 tcatcctgct gctggtcatc tacacggctg tcttcacgcc ctactcagcc gccttcctgc
      901 tcagcgatca ggacgaatca cggcgtgggg cctgcagcta tacctgcagt cccctcactg
      961 tggtggatct catcgtggac atcatgttcg tcgtggacat cgtcatcaac ttccgcacca
     1021 cctatgtcaa caccaatgat gaggtggtca gccacccccg ccgcatcgcc gtccactact
     1081 tcaagggctg gttcctcatt gacatggtgg ccgccatccc tttcgacctc ctgatcttcc
     1141 gcactggctc cgatgagacc acaaccctga ttgggctatt gaagacagcg cggctgctgc
     1201 ggctggtgcg cgtagcacgg aagctggacc gctactctga gtatggggcg gctgtgctct
     1261 tcttgctcat gtgcaccttc gcgctcatag cgcactggct ggcctgcatc tggtacgcca
     1321 tcggcaatgt ggagcggccc tacctagaac acaagatcgg ctggctggac agcctgggtg
     1381 tgcagcttgg caagcgctac aacggcagcg acccagcctc gggcccctcg gtgcaggaca
     1441 agtatgtcac agccctctac ttcaccttca gcagcctcac cagcgtgggc ttcggcaatg
     1501 tctcgcccaa caccaactcc gagaaggtct tctccatctg cgtcatgctc atcggctccc
     1561 tgatgtacgc cagcatcttc gggaacgtgt ccgcgatcat ccagcgcctg tactcgggca
     1621 ccgcgcgcta ccacacgcag atgctgcgtg tcaaggagtt catccgcttc caccagatcc
     1681 ccaacccact gcgccagcgc ctggaggagt atttccagca cgcctggtcc tacaccaatg
     1741 gcattgacat gaacgcggtg ctgaagggct tccccgagtg cctgcaggct gacatctgcc
     1801 tgcacctgca ccgcgcactg ctgcagcact gcccagcttt cagcggcgcc ggcaagggct
     1861 gcctgcgcgc gctagccgtc aagttcaaga ccacccacgc gccgcctggg gacacgctgg
     1921 tgcacctcgg cgacgtgctc tccaccctct acttcatctc ccgaggctcc atcgagatcc
     1981 tgcgcgacga cgtggtcgtg gccatcctag gaaagaatga catctttggg gaacccgtca
     2041 gcctccatgc ccagccaggc aagtccagtg cagacgtgcg ggctctgacc tactgcgacc
     2101 tgcacaagat ccagcgggca gatctgctgg aggtgctgga catgtacccg gcctttgcgg
     2161 agagcttctg gagtaagctg gaggtcacct tcaacctgcg ggacgctcct ggcagccaag
     2221 accaccaagg tttctttctc agtgacaacc agtcagatgc agcccctccc ctgagcatct
     2281 cagatgcatc tggcctctgg cctgagctac tgcaggaaat gcccccaagg cacagccccc
     2341 aaagccctca ggaagaccca gattgctggc ctctgaagct gggctccagg ctagagcagc
     2401 tccaggccca gatgaacagg ctggagtccc gcgtgtcctc agacctcagc cgcatcttgc
     2461 agctcctcca gaagcccatg ccccagggcc acgccagcta cattctggaa gcccctgcct
     2521 ccaatgacct ggccttggtt cctatagcct cggagacgac gagtccaggg cccaggctgc
     2581 cccagggctt tctgcctcct gcacagaccc caagctatgg agacttggat gactgtagtc
     2641 caaagcacag gaactcctcc cccaggatgc ctcacctggc tgtggcaacg gacaaaactc
     2701 tggcaccatc ctcagaacag gaacagcctg aggggctctg gccaccccta gcctcacctc
     2761 tacatcccct ggaagtacaa ggactcatct gtggtccctg cttctcctcc ctccctgaac
     2821 accttggctc tgttcccaag cagctggact tccagagaca tggctcagat cctggatttg
     2881 cagggagttg gggccactga actccaagat aaagacacca tgaggggact gaaggtgggc
     2941 aaggtgagag ttaaggatct tggggaggtg gccgggtgca gtggctcgcc tgtaatccca
     3001 gcactttggg aggccgaggc gggcggatca gaccatcctg gctaacacgg tgaaacccca
     3061 cctctactaa aattaaaaaa gaaaaaaaat agccgggcgt ggtggcaggc gcctgtaatc
     3121 ccagctactg gggaggctga ggcaggagaa tggcatgaac ccgggaggtg gaggttgcag
     3181 ggagccgagg ccgcaccact gcactccagc ctgggtgaca gagtgagact ccaactcaaa
     3241 aaaaaaaaaa aaaaagatct tggggaggca gacagccccc cagatgggcc tctcctaaag
     3301 tagctacaaa ctgctgatcc aggtgaccca ggatggcgtg ggtgaagaag ctcacgactt
     3361 ttcccagcct cctccagggc tccatttaaa cagcaagcct ggtgcagggt gggagagtct
     3421 caggtgtgga ggcagcttac aggattgagg gggcagtgaa gaaagaggtt tctgatctac
     3481 atgagtacct tgctctgagc ctcccagctc agaaccctcc agcacctcat ggctcagcac
     3541 caaggcccgg ggttggtcag aactcttacc atgagcctct gacctggctg gagatggagg
     3601 tatgttctgt ggcagacatg tcaggacagt cctccagccc tctgctcctg atggttctgt
     3661 gacattgggt ctcttgaggg cagtggagtg tcacacagct aataaagtac acatttcatg
     3721 ttgga
//
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