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NCBI Reference Sequence: XM_017025178.3
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LOCUS XM_017025178 3725 bp mRNA linear PRI 25-AUG-2024 DEFINITION PREDICTED: Homo sapiens potassium voltage-gated channel subfamily H member 6 (KCNH6), transcript variant X4, mRNA. ACCESSION XM_017025178 VERSION XM_017025178.3 DBLINK BioProject: PRJNA168 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 5, 2022 this sequence version replaced XM_017025178.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_000001405.40-RS_2024_08 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; RefSeqFE; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 08/23/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3725 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="17" gene 1..3725 /gene="KCNH6" /gene_synonym="ERG-2; ERG2; hERG-2; HERG2; Kv11.2" /note="potassium voltage-gated channel subfamily H member 6; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 26 ESTs, 7 long SRA reads, 14 Proteins, and 96% coverage of the annotated genomic feature by RNAseq alignments, including 7 samples with support for all annotated introns" /db_xref="GeneID:81033" /db_xref="HGNC:HGNC:18862" /db_xref="MIM:608168" CDS 57..2900 /gene="KCNH6" /gene_synonym="ERG-2; ERG2; hERG-2; HERG2; Kv11.2" /codon_start=1 /product="potassium voltage-gated channel subfamily H member 6 isoform X4" /protein_id="XP_016880667.1" /db_xref="GeneID:81033" /db_xref="HGNC:HGNC:18862" /db_xref="MIM:608168" /translation="MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYC NDGFCELFGYSRVEVMQQPCTCDFLTGPNTPSSAVSRLAQALLGAEECKVDILYYRKD ASSFRCLVDVVPVKNEDGAVIMFILNFEDLAQLLAKCSSRSLSQRLLSQSFLGSEGSH GRPGGPGPGTGRGKYRTISQIPQFTLNFVEFNLEKHRSSSTTEIEIIAPHKVVERTQN VTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPY SAAFLLSDQDESRRGACSYTCSPLTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHP RRIAVHYFKGWFLIDMVAAIPFDLLIFRTGSDETTTLIGLLKTARLLRLVRVARKLDR YSEYGAAVLFLLMCTFALIAHWLACIWYAIGNVERPYLEHKIGWLDSLGVQLGKRYNG SDPASGPSVQDKYVTALYFTFSSLTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIF GNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMN AVLKGFPECLQADICLHLHRALLQHCPAFSGAGKGCLRALAVKFKTTHAPPGDTLVHL GDVLSTLYFISRGSIEILRDDVVVAILGKNDIFGEPVSLHAQPGKSSADVRALTYCDL HKIQRADLLEVLDMYPAFAESFWSKLEVTFNLRDAPGSQDHQGFFLSDNQSDAAPPLS ISDASGLWPELLQEMPPRHSPQSPQEDPDCWPLKLGSRLEQLQAQMNRLESRVSSDLS RILQLLQKPMPQGHASYILEAPASNDLALVPIASETTSPGPRLPQGFLPPAQTPSYGD LDDCSPKHRNSSPRMPHLAVATDKTLAPSSEQEQPEGLWPPLASPLHPLEVQGLICGP CFSSLPEHLGSVPKQLDFQRHGSDPGFAGSWGH" ORIGIN 1 ggagacgccg ggagccagtg gcgcctgtgg ctccgggcag gggccgcggc cgaaagatgc 61 cggtccgcag gggccacgtc gctccccaaa acacttacct ggacaccatc atccgcaagt 121 tcgagggcca aagtcggaag ttcctgattg ccaatgctca gatggagaac tgcgccatca 181 tttactgcaa cgacggcttc tgcgaactct tcggctactc ccgagtggag gtgatgcagc 241 aaccctgcac ctgcgacttc ctcacaggcc ccaacacacc aagcagcgcc gtgtcccgcc 301 tagcgcaggc cctgctgggg gctgaggagt gcaaggtgga catcctctac taccgcaagg 361 atgcctccag cttccgctgc ctggtagatg tggtgcccgt gaagaacgag gacggggctg 421 tcatcatgtt cattctcaac ttcgaggacc tggcccagct cctggccaag tgcagcagcc 481 gcagcttgtc ccagcgcctg ttgtcccaga gcttcctggg ctccgagggc tctcatggca 541 ggccaggcgg accagggcca ggcacaggca ggggcaagta caggaccatc agccagatcc 601 cacagttcac gctcaacttc gtggagttca acttggagaa gcaccgctcc agctccacca 661 cggagattga gatcatcgcg ccccataagg tggtggagcg gacacagaac gtcactgaga 721 aggtcaccca ggtcctgtcc ctgggcgcgg atgtgctgcc ggagtacaag ctgcaggcgc 781 cgcgcatcca ccgctggacc atcctgcact acagcccctt caaggccgtg tgggactggc 841 tcatcctgct gctggtcatc tacacggctg tcttcacgcc ctactcagcc gccttcctgc 901 tcagcgatca ggacgaatca cggcgtgggg cctgcagcta tacctgcagt cccctcactg 961 tggtggatct catcgtggac atcatgttcg tcgtggacat cgtcatcaac ttccgcacca 1021 cctatgtcaa caccaatgat gaggtggtca gccacccccg ccgcatcgcc gtccactact 1081 tcaagggctg gttcctcatt gacatggtgg ccgccatccc tttcgacctc ctgatcttcc 1141 gcactggctc cgatgagacc acaaccctga ttgggctatt gaagacagcg cggctgctgc 1201 ggctggtgcg cgtagcacgg aagctggacc gctactctga gtatggggcg gctgtgctct 1261 tcttgctcat gtgcaccttc gcgctcatag cgcactggct ggcctgcatc tggtacgcca 1321 tcggcaatgt ggagcggccc tacctagaac acaagatcgg ctggctggac agcctgggtg 1381 tgcagcttgg caagcgctac aacggcagcg acccagcctc gggcccctcg gtgcaggaca 1441 agtatgtcac agccctctac ttcaccttca gcagcctcac cagcgtgggc ttcggcaatg 1501 tctcgcccaa caccaactcc gagaaggtct tctccatctg cgtcatgctc atcggctccc 1561 tgatgtacgc cagcatcttc gggaacgtgt ccgcgatcat ccagcgcctg tactcgggca 1621 ccgcgcgcta ccacacgcag atgctgcgtg tcaaggagtt catccgcttc caccagatcc 1681 ccaacccact gcgccagcgc ctggaggagt atttccagca cgcctggtcc tacaccaatg 1741 gcattgacat gaacgcggtg ctgaagggct tccccgagtg cctgcaggct gacatctgcc 1801 tgcacctgca ccgcgcactg ctgcagcact gcccagcttt cagcggcgcc ggcaagggct 1861 gcctgcgcgc gctagccgtc aagttcaaga ccacccacgc gccgcctggg gacacgctgg 1921 tgcacctcgg cgacgtgctc tccaccctct acttcatctc ccgaggctcc atcgagatcc 1981 tgcgcgacga cgtggtcgtg gccatcctag gaaagaatga catctttggg gaacccgtca 2041 gcctccatgc ccagccaggc aagtccagtg cagacgtgcg ggctctgacc tactgcgacc 2101 tgcacaagat ccagcgggca gatctgctgg aggtgctgga catgtacccg gcctttgcgg 2161 agagcttctg gagtaagctg gaggtcacct tcaacctgcg ggacgctcct ggcagccaag 2221 accaccaagg tttctttctc agtgacaacc agtcagatgc agcccctccc ctgagcatct 2281 cagatgcatc tggcctctgg cctgagctac tgcaggaaat gcccccaagg cacagccccc 2341 aaagccctca ggaagaccca gattgctggc ctctgaagct gggctccagg ctagagcagc 2401 tccaggccca gatgaacagg ctggagtccc gcgtgtcctc agacctcagc cgcatcttgc 2461 agctcctcca gaagcccatg ccccagggcc acgccagcta cattctggaa gcccctgcct 2521 ccaatgacct ggccttggtt cctatagcct cggagacgac gagtccaggg cccaggctgc 2581 cccagggctt tctgcctcct gcacagaccc caagctatgg agacttggat gactgtagtc 2641 caaagcacag gaactcctcc cccaggatgc ctcacctggc tgtggcaacg gacaaaactc 2701 tggcaccatc ctcagaacag gaacagcctg aggggctctg gccaccccta gcctcacctc 2761 tacatcccct ggaagtacaa ggactcatct gtggtccctg cttctcctcc ctccctgaac 2821 accttggctc tgttcccaag cagctggact tccagagaca tggctcagat cctggatttg 2881 cagggagttg gggccactga actccaagat aaagacacca tgaggggact gaaggtgggc 2941 aaggtgagag ttaaggatct tggggaggtg gccgggtgca gtggctcgcc tgtaatccca 3001 gcactttggg aggccgaggc gggcggatca gaccatcctg gctaacacgg tgaaacccca 3061 cctctactaa aattaaaaaa gaaaaaaaat agccgggcgt ggtggcaggc gcctgtaatc 3121 ccagctactg gggaggctga ggcaggagaa tggcatgaac ccgggaggtg gaggttgcag 3181 ggagccgagg ccgcaccact gcactccagc ctgggtgaca gagtgagact ccaactcaaa 3241 aaaaaaaaaa aaaaagatct tggggaggca gacagccccc cagatgggcc tctcctaaag 3301 tagctacaaa ctgctgatcc aggtgaccca ggatggcgtg ggtgaagaag ctcacgactt 3361 ttcccagcct cctccagggc tccatttaaa cagcaagcct ggtgcagggt gggagagtct 3421 caggtgtgga ggcagcttac aggattgagg gggcagtgaa gaaagaggtt tctgatctac 3481 atgagtacct tgctctgagc ctcccagctc agaaccctcc agcacctcat ggctcagcac 3541 caaggcccgg ggttggtcag aactcttacc atgagcctct gacctggctg gagatggagg 3601 tatgttctgt ggcagacatg tcaggacagt cctccagccc tctgctcctg atggttctgt 3661 gacattgggt ctcttgaggg cagtggagtg tcacacagct aataaagtac acatttcatg 3721 ttgga //
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