Homo sapiens CD74 molecule (CD74), RefSeqGene on chromosome 5

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CD74 supports accumulation and function of regulatory T cells in tumors. [Nat Commun. 2024]
CD74 supports accumulation and function of regulatory T cells in tumors.
Bonnin E, Rodrigo Riestra M, Marziali F, Mena Osuna R, Denizeau J, Maurin M, Saez JJ, Jouve M, Bonté PE, Richer W, et al. Nat Commun. 2024 May 3; 15(1):3749. Epub 2024 May 3.
CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors. [Cancer Immunol Immunother. 2024]
CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors.
Wang J, Li X, Xiao G, Desai J, Frentzas S, Wang ZM, Xia Y, Li B. Cancer Immunol Immunother. 2024 Jan 27; 73(2):36. Epub 2024 Jan 27.
CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells. [FEBS J. 2024]
CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells.
Xu X, Li Y, Xu R, Meng Y, Li Z, Zuo D, Wu Y. FEBS J. 2024 Mar; 291(6):1199-1219. Epub 2024 Jan 12.

RefSeq alternative splicing
See 5 reference mRNA sequence splice variants for the CD74 gene.

Protein
Protein sequence from Nucleotide coding region
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RNA
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Nucleotide