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Human Ig rearranged anti-myelin H-chain mRNA V-J4-region, hybridoma AE6-5, 5' end

GenBank: M29470.1

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LOCUS       HUMIGHCV                 489 bp    mRNA    linear   PRI 26-JUL-2016
DEFINITION  Human Ig rearranged anti-myelin H-chain mRNA V-J4-region, hybridoma
            AE6-5, 5' end.
ACCESSION   M29470
VERSION     M29470.1
KEYWORDS    J-region; V-region; autoantibody; immunoglobulin heavy chain;
            processed gene; variable region subgroup VH-III.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Spatz,L.A., Wong,K.K., Williams,M., Desai,R., Golier,J.,
            Berman,J.E., Alt,F.W. and Latov,N.
  TITLE     Cloning and sequence analysis of the VH and VL regions of an
            anti-myelin/DNA antibody from a patient with peripheral neuropathy
            and chronic lymphocytic leukemia
  JOURNAL   J. Immunol. 144 (7), 2821-2828 (1990)
   PUBMED   2156935
COMMENT     Draft entry and printed sequence kindly submitted by L.A.Spatz,
            26-OCT-1989, for release after publication. Columbia University,
            Department of Neurology BB-322, 630 W. 168th street, New York, NY
            10032.
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /map="14q32.33"
     gene            1..489
                     /gene="IGH@"
     CDS             64..>489
                     /gene="IGH@"
                     /note="V-J4-region precursor"
                     /codon_start=1
                     /product="IgH"
                     /protein_id="AAA52856.1"
                     /db_xref="GDB:G00-118-731"
                     /translation="MEFGLSWLFLVAILKGVQCEVQLLESGGGLVQPEGSLRLSCAVS
                     GFTFSSFAMTWVRQAPGKGLEWVSAISTSGGSTYYAESVKGRFTISRDNSMHTLYLQM
                     NSLRAEDTAVYYCAKGPTYCSRISCPPDYWGQGTLVTVSS"
     sig_peptide     64..120
                     /gene="IGH@"
                     /note="Ig H-chain signal peptide"
     mat_peptide     121..>489
                     /gene="IGH@"
                     /product="Ig H-chain"
     misc_recomb     450..451
                     /gene="IGH@"
ORIGIN      
        1 cccagccctg ggattttcag gtgttttcat ttggtgatca ggactgaaca gagagaactc
       61 accatggagt ttgggctgag ctggcttttt cttgtggcta ttttaaaagg tgtccagtgt
      121 gaggtgcagc tgttggagtc tgggggaggc ttggtacagc ctgaggggtc cctgagactc
      181 tcctgtgcag tctccggatt cacttttagc agctttgcca tgacctgggt ccgccaggct
      241 ccagggaagg ggctggagtg ggtctcagct attagtacta gtggtggtag cacatactac
      301 gcagagtccg tgaagggccg cttcaccatc tccagagaca attccatgca cacgctgtat
      361 ctgcaaatga acagcctgag agccgaggac acggccgtct attactgtgc gaaaggtcct
      421 acatattgta gtagaatcag ctgccctccg gactactggg gccagggaac cctggtcacc
      481 gtctcctca
//
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