Mus musculus gamma-glutamylcysteine synthetase heavy subunit (Ggcs-hs) - Nucleotide

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Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression. [Nat Commun. 2024]
Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression.
Asantewaa G, Tuttle ET, Ward NP, Kang YP, Kim Y, Kavanagh ME, Girnius N, Chen Y, Rodriguez K, Hecht F, et al. Nat Commun. 2024 Jul 21; 15(1):6152. Epub 2024 Jul 21.
Neuronal glutathione depletion elevates the Aβ42/Aβ40 ratio and tau aggregation in Alzheimer's disease mice. [FEBS Lett. 2024]
Neuronal glutathione depletion elevates the Aβ42/Aβ40 ratio and tau aggregation in Alzheimer's disease mice.
Hashim KNB, Matsuba Y, Takahashi M, Kamano N, Tooyama I, Saido TC, Hashimoto S. FEBS Lett. 2024 Jul; 598(13):1576-1590. Epub 2024 May 24.
Prevention of age-related truncation of γ-glutamylcysteine ligase catalytic subunit (GCLC) delays cataract formation. [Sci Adv. 2024]
Prevention of age-related truncation of γ-glutamylcysteine ligase catalytic subunit (GCLC) delays cataract formation.
Wei Z, Hao C, Radeen KR, Srinivasagan R, Chen JK, Sharma S, McGee-Lawrence ME, Hamrick MW, Monnier VM, Fan X. Sci Adv. 2024 Apr 26; 10(17):eadl1088. Epub 2024 Apr 26.

RefSeq alternative splicing
See 2 reference mRNA sequence splice variants for the Gclc gene.

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Nucleotide