U.S. flag

An official website of the United States government

Homo sapiens probable mannose-binding C-type lectin DC-SIGN gene, complete cds

GenBank: AF209479.1

FASTA Graphics 

LOCUS       AF209479                4424 bp    DNA     linear   PRI 17-SEP-2000
DEFINITION  Homo sapiens probable mannose-binding C-type lectin DC-SIGN gene,
            complete cds.
ACCESSION   AF209479
VERSION     AF209479.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4424)
  AUTHORS   Soilleux,E.J., Barten,R. and Trowsdale,J.
  TITLE     DC-SIGN; a related gene, DC-SIGNR; and CD23 form a cluster on 19p13
  JOURNAL   J. Immunol. 165 (6), 2937-2942 (2000)
   PUBMED   10975799
REFERENCE   2  (bases 1 to 4424)
  AUTHORS   Soilleux,E.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-NOV-1999) Department of Pathology, University of
            Cambridge, Tennis Court Road, Cambridge, Cambs CB2 1QP, UK
FEATURES             Location/Qualifiers
     source          1..4424
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13; adjacent to CD23"
     mRNA            join(<42..87,188..247,874..945,1318..1887,2312..2463,
                     3185..3297,4167..>4368)
                     /product="probable mannose-binding C-type lectin DC-SIGN"
     CDS             join(42..87,188..247,874..945,1318..1887,2312..2463,
                     3185..3297,4167..4368)
                     /note="type II integral membrane protein"
                     /codon_start=1
                     /product="probable mannose-binding C-type lectin DC-SIGN"
                     /protein_id="AAG13814.1"
                     /translation="MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGPLV
                     LQLLSFTLLAGLLVQVSKVPSSISQEQSRQDAIYQNLTQLKAAVGELSEKSKLQEIYQ
                     ELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWLKAAVGEL
                     PEKSKMQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQE
                     LTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRN
                     WHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSP
                     LLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKCNLAKFWICKKSAASCSRDEEQFL
                     SPAPATPNPPPA"
     exon            <42..87
                     /note="encodes cytoplasmic domain"
                     /number=1
     exon            188..247
                     /note="encodes cytoplasmic domain"
                     /number=2
     exon            874..945
                     /note="encodes transmembrane region"
                     /number=3
     exon            1318..1887
                     /number=4
     repeat_region   1392..1874
                     /note="encodes likely alpha helical coiled-coil region
                     that forms the neck of the protein"
                     /rpt_type=tandem
                     /rpt_unit_range=1392..1460
     exon            2312..2463
                     /note="encodes C-type lectin domain CRD1 involved in the
                     formation of the carbohydrate recognition domain"
                     /number=5
     exon            3185..3297
                     /note="encodes C-type lectin domain CRD2 involved in the
                     formation of the carbohydrate recognition domain"
                     /number=6
     exon            4167..>4368
                     /note="encodes C-type lectin domain CRD3 involved in the
                     formation of the carbohydrate recognition domain"
                     /number=7
ORIGIN      
        1 ctaaagcagg agttctggac actgggggag agtggggtga catgagtgac tccaaggaac
       61 caagactgca gcagctgggc ctcctgggtg aggctgggtt gggacgctgg gattctggga
      121 agggggaagg gatggccagc catggcctca gcctgcccag gctctgattt cacgtctatc
      181 cattcagagg aggaacagct gagaggcctt ggattccgac agactcgagg atacaagagc
      241 ttagcaggta gagaggactt agcagtttgg gaggagagac gagagactcc tggactcctg
      301 ggtcctgagg agctggacgc tggggcctgg actcttgggt cctggggatg tggggctagg
      361 ggcctggact cctgggacct gaggaggttg agtttggggc ctgaattcct ggttcctggg
      421 aaggtggagg ctggggccaa gactcctggg ttctggggag gtagaagttg aagcctgggt
      481 tcctgggtcc tggggaggtg gggtcagggg cctagactcc tgggtcctgg agaggtgggg
      541 gcctgggcct ggactcctgg gtcatgggga ggtggggact tgggcctggg ttcctgggac
      601 ctggggatgt aggggctggg acccagattc ttgggtcttg gggaggtggg agcaggtacc
      661 tgggttactg ggacctgggg aaggggaggc tgggtcctgg gcccctgggt cctggggagg
      721 tgggagctgg gggcctgggt tccagggacc tgggaatgta gaggctgggg ctggggttcc
      781 tgggtcctgg ggtgctgagg gatttagacc aggctctccc tgggccaggc tccggtggga
      841 cactggcagg ctgacgcatg tatcttctct cagggtgtct tggccatggt cccctggtgc
      901 tgcaactcct ctccttcacg ctcttggctg ggctccttgt ccaaggtcag gggcaggttc
      961 tgagggtgtg gggtccccac gcctggcttt tggctgtgga cacagcctgg ggctgccaga
     1021 tctgggaggg aggtggggtt gagagccaag atgttgtccc tgggggtctg taggggcctc
     1081 tcccacagcc catccccact ttagggcagg acaggagagg gaggaggagg aggacaggaa
     1141 gaatctggct ctccttggcc ttctgtgctg ccttctccag gtgtcagtgt tcttcatctt
     1201 caaaggggat taaccaagac cttggctctc acaaatgatg tccctatggg gctcagttca
     1261 aggcttggca cacagtaggt gtctaataat tgcagttcct tttttatttt ggcccagtgt
     1321 ccaaggtccc cagctccata agtcaggaac aatccaggca agacgcgatc taccagaacc
     1381 tgacccagct taaagctgca gtgggtgagc tctcagagaa atccaagctg caggagatct
     1441 accaggagct gacccagctg aaggctgcag tgggtgagct tccagagaaa tctaagctgc
     1501 aggagatcta ccaggagctg acccggctga aggctgcagt gggtgagctt ccagagaaat
     1561 ctaagctgca ggagatctac caggagctga cctggctgaa ggctgcagtg ggtgagcttc
     1621 cagagaaatc taagatgcag gagatctacc aggagctgac tcggctgaag gctgcagtgg
     1681 gtgagcttcc agagaaatct aagcagcagg agatctacca ggagctgacc cggctgaagg
     1741 ctgcagtggg tgagcttcca gagaaatcta agcagcagga gatctaccag gagctgaccc
     1801 ggctgaaggc tgcagtgggt gagcttccag agaaatctaa gcagcaggag atctaccagg
     1861 agctgaccca gctgaaggct gcagtgggtg agtatctgga accaggcttc ttgggcctga
     1921 gatggtcgtt gtgtggtgtg agtttgcttg agtcactgac cctgcctgag caagtttctt
     1981 catctgtgaa atgagaacac agggtaactg tgatcattgc cctcagtgtt cacagtgggc
     2041 caggtacaca acaggcactc agttaagcca gtctcctgcc ttctgttctg agttctaaag
     2101 ccccaacttc tcctagtctg gaggagatgg ggccaggact cctgggttct catggggatg
     2161 ggggagggtc tcgggaagtg gggaggggaa tggtctaccc ggcgtggaca gtcaaggaag
     2221 gactctgact ctcaagacct tgaaggctgg gcaggtacag gaatatggac aacctaatct
     2281 aagcccagcc ctgaccagcc tcccccaaca gaacgcctgt gccacccctg tccctgggaa
     2341 tggacattct tccaaggaaa ctgttacttc atgtctaact cccagcggaa ctggcacgac
     2401 tccatcaccg cctgcaaaga agtgggggcc cagctcgtcg taatcaaaag tgctgaggag
     2461 caggtacacc tggtggggat ccccgtcctg gcctagggca tggcttctgg ccaactgggg
     2521 aggaggtgct cagagatgac tttgcagaag aggggttttg ctccacttgg aaagaaggga
     2581 ggagaaggat atgaatgagg gagtctcaag tacccttaga gcagatacaa accaaatctg
     2641 aacatgtgtg aatgctccgg aaaaaaacat caaatgtaag caaacccctg cagcatgctg
     2701 caagaggtta acaaccagct ctctggagga agaatcctga tgggtcgtgt ttgccagttt
     2761 ccctggtgta aatattccca tggtggctga ttttcaagct gtcgttgtga tgtcactcag
     2821 tgcagagctg aaaggagatg tgcatgacca gcagttagga aatggttgct tctggctcca
     2881 acacattaag cccagttatg agtaaatgtg catggacatg cacagaacat gtgaaatgga
     2941 taaacatgca gtattagcaa gagggtgtga ggagaggcca gctgtgcatg gatgtgtgca
     3001 tgtcaggaca catgtgccgt gggatacaca tgtgagaggg actcagacac gagggggctc
     3061 aggacctagt ataccagaag gctgtaggtt agcctacaag cagaacttcc taccaagaga
     3121 tggggagaca gagcctggaa aatgggaagc agagctccct cctgactcct cctgtaccct
     3181 ccagaacttc ctacagctgc agtcttccag aagtaaccgc ttcacctgga tgggactttc
     3241 agatctaaat caggaaggca cgtggcaatg ggtggacggc tcacctctgt tgcccaggta
     3301 gatctcagaa ggggcaccct atccactggg gctggaattg tgaaactctg atttgaactt
     3361 tccctgggga tcctccccaa ctccctgaca ccctagaccc aagaatctgg aggttttact
     3421 gagttgagga aggtggtctt catacccact tccagacagc atggcaggtg cctagaattc
     3481 caccagcaga gctgcaggag gagcctgcca ccggggaggt tgttattaaa tataatgtta
     3541 ttaataggaa gttctgaggt ccagtaaggc caccagctca ggagacacct gccattgtga
     3601 atagcttctc atatacacag atccctagag agaggacaca tcacagctgg gggccacctg
     3661 gggaagcacc agggtctgtt atgagtcaga gtggtgggga ggggggactg tgggccagag
     3721 cctttattat ggtttctgtg gaaaggaaag gtcaaggcca ggtgaacagg cttaggattg
     3781 ggaagtgtga agcatttttt gggctctggg gcacaggggc tgcccctcgc tgtctgacac
     3841 ctggccttgg ggtgattagt acaggatagt ggcttggagt acaagagccc agtaaggcag
     3901 gtcgctggag gtgtggactc cagactggtt ggcttgtatt tgaaaatcac acactcaata
     3961 ggtggagtcc acccaaggac aggttgtgag aagagaggca ggaactcaag gcatcgtgag
     4021 tcaggcatat tatcaggtat gcagagggat tcaagtccag catacacacg cagggcagat
     4081 gttaaggcat caagatgaca gaaggtagaa acacagctca tgtagctggc ggggacagag
     4141 gctcacattc cgcatgggct ttgcagcttc aagcagtatt ggaacagagg agagcccaac
     4201 aacgttgggg aggaagactg cgcggaattt agtggcaatg gctggaacga cgacaaatgt
     4261 aatcttgcca aattctggat ctgcaaaaag tccgcagcct cctgctccag ggatgaagaa
     4321 cagtttcttt ctccagcccc tgccacccca aacccccctc ctgcgtagca gaacttcacc
     4381 cccttttaag ctacagttcc ttctctccat ccttcgacct ttag
//
Feature
Display: FASTA GenBank Help
Details

Supplemental Content

Change region shown

Customize view

Reference sequence information

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
External link. Please review our privacy policy.