Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis.
McLaughlin MT, Sun MR, Beames TG, Steward AC, Theisen JWM, Chung HM, Everson JL, Moskowitz IP, Sheets MD, Lipinski RJ. Dev Dyn. 2023 Apr; 252(4):483-494. Epub 2022 Dec 19.