Deficiency of Tlr7 and Irf7 in mice increases the severity of COVID-19 through the reduced interferon production.
Wang C, Khatun MS, Ellsworth CR, Chen Z, Islamuddin M, Nisperuza Vidal AK, Afaque Alam M, Liu S, Mccombs JE, Maness NJ, et al. Commun Biol. 2024 Sep 17; 7(1):1162. Epub 2024 Sep 17.