Homo sapiens deoxyribonuclease I-like 3, mRNA (cDNA clone MGC:27146 IM - Nucleotide

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A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models. [JCI Insight. 2024]
A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models.
Stabach PR, Sims D, Gomez-Bañuelos E, Zehentmeier S, Dammen-Brower K, Bernhisel A, Kujawski S, Lopez SG, Petri M, Goldman DW, et al. JCI Insight. 2024 Jun 18; 9(14). Epub 2024 Jun 18.
Double-negative B cells and DNASE1L3 colocalise with microbiota in gut-associated lymphoid tissue. [Nat Commun. 2024]
Double-negative B cells and DNASE1L3 colocalise with microbiota in gut-associated lymphoid tissue.
Montorsi L, Pitcher MJ, Zhao Y, Dionisi C, Demonti A, Tull TJ, Dhami P, Ellis RJ, Bishop C, Sanderson JD, et al. Nat Commun. 2024 May 14; 15(1):4051. Epub 2024 May 14.
[Decreased DNase1L3 secretion and associated antibodies induce impaired degradation of NETs in patients with sporadic SLE]. [Xi Bao Yu Fen Zi Mian Yi Xue Z...]
[Decreased DNase1L3 secretion and associated antibodies induce impaired degradation of NETs in patients with sporadic SLE].
Huang J, Mao T, Zhang J, Li Z, Wu Q. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2024 Jan; 40(1):43-50.

RefSeq alternative splicing
See 2 reference mRNA sequence splice variants for the DNASE1L3 gene.

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Nucleotide